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Volumn 51, Issue 3, 2012, Pages 418-430

MEPE is a novel regulator of growth plate cartilage mineralization

Author keywords

ASARM; Chondrocyte; Growth plate; MEPE; Mineralization

Indexed keywords

ALKALINE PHOSPHATASE; ASARM PROTEIN; MATRIX EXTRACELLULAR PHOSPHOGLYCOPROTEIN; MESSENGER RNA; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84864053375     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.06.022     Document Type: Article
Times cited : (43)

References (69)
  • 1
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • Kronenberg H.M. Developmental regulation of the growth plate. Nature 2003, 423:332-336.
    • (2003) Nature , vol.423 , pp. 332-336
    • Kronenberg, H.M.1
  • 2
    • 0029061758 scopus 로고
    • Molecular biology of matrix vesicles
    • Anderson H.C. Molecular biology of matrix vesicles. Clin Orthop Relat Res 1995, 266-280.
    • (1995) Clin Orthop Relat Res , pp. 266-280
    • Anderson, H.C.1
  • 3
    • 0021339769 scopus 로고
    • Can biological calcification occur in the presence of pyrophosphate?
    • Meyer J.L. Can biological calcification occur in the presence of pyrophosphate?. Arch Biochem Biophys 1984, 231:1-8.
    • (1984) Arch Biochem Biophys , vol.231 , pp. 1-8
    • Meyer, J.L.1
  • 4
    • 0034235036 scopus 로고    scopus 로고
    • MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
    • Rowe P.S., de Zoysa P.A., Dong R., Wang H.R., White K.E., Econs M.J., et al. MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia. Genomics 2000, 67:54-68.
    • (2000) Genomics , vol.67 , pp. 54-68
    • Rowe, P.S.1    de Zoysa, P.A.2    Dong, R.3    Wang, H.R.4    White, K.E.5    Econs, M.J.6
  • 5
    • 0037237957 scopus 로고    scopus 로고
    • Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins
    • Fisher L.W., Fedarko N.S. Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins. Connect Tissue Res 2003, 44(Suppl. 1):33-40.
    • (2003) Connect Tissue Res , vol.44 , Issue.SUPPL. 1 , pp. 33-40
    • Fisher, L.W.1    Fedarko, N.S.2
  • 7
    • 0028844750 scopus 로고
    • Mapping of the human dentin matrix acidic phosphoprotein gene (DMP1) to the dentinogenesis imperfecta type II critical region at chromosome 4q21
    • Aplin H.M., Hirst K.L., Crosby A.H., Dixon M.J. Mapping of the human dentin matrix acidic phosphoprotein gene (DMP1) to the dentinogenesis imperfecta type II critical region at chromosome 4q21. Genomics 1995, 30:347-349.
    • (1995) Genomics , vol.30 , pp. 347-349
    • Aplin, H.M.1    Hirst, K.L.2    Crosby, A.H.3    Dixon, M.J.4
  • 8
  • 9
    • 2442675051 scopus 로고    scopus 로고
    • Matrix extracellular phosphoglycoprotein (MEPE) is highly expressed in osteocytes in human bone
    • Nampei A., Hashimoto J., Hayashida K., Tsuboi H., Shi K., Tsuji I., et al. Matrix extracellular phosphoglycoprotein (MEPE) is highly expressed in osteocytes in human bone. J Bone Miner Metab 2004, 22:176-184.
    • (2004) J Bone Miner Metab , vol.22 , pp. 176-184
    • Nampei, A.1    Hashimoto, J.2    Hayashida, K.3    Tsuboi, H.4    Shi, K.5    Tsuji, I.6
  • 10
    • 0035874943 scopus 로고    scopus 로고
    • Mepe, the gene encoding a tumor-secreted protein in oncogenic hypophosphatemic osteomalacia, is expressed in bone
    • Argiro L., Desbarats M., Glorieux F.H., Ecarot B. Mepe, the gene encoding a tumor-secreted protein in oncogenic hypophosphatemic osteomalacia, is expressed in bone. Genomics 2001, 74:342-351.
    • (2001) Genomics , vol.74 , pp. 342-351
    • Argiro, L.1    Desbarats, M.2    Glorieux, F.H.3    Ecarot, B.4
  • 11
    • 0034680755 scopus 로고    scopus 로고
    • Identification of osteoblast/osteocyte factor 45 (OF45), a bone-specific cDNA encoding an RGD-containing protein that is highly expressed in osteoblasts and osteocytes
    • Petersen D.N., Tkalcevic G.T., Mansolf A.L., Rivera-Gonzalez R., Brown T.A. Identification of osteoblast/osteocyte factor 45 (OF45), a bone-specific cDNA encoding an RGD-containing protein that is highly expressed in osteoblasts and osteocytes. J Biol Chem 2000, 275:36172-36180.
    • (2000) J Biol Chem , vol.275 , pp. 36172-36180
    • Petersen, D.N.1    Tkalcevic, G.T.2    Mansolf, A.L.3    Rivera-Gonzalez, R.4    Brown, T.A.5
  • 12
    • 0037449817 scopus 로고    scopus 로고
    • Targeted disruption of the osteoblast/osteocyte factor 45 gene (OF45) results in increased bone formation and bone mass
    • Gowen L.C., Petersen D.N., Mansolf A.L., Qi H., Stock J.L., Tkalcevic G.T., et al. Targeted disruption of the osteoblast/osteocyte factor 45 gene (OF45) results in increased bone formation and bone mass. J Biol Chem 2003, 278:1998-2007.
    • (2003) J Biol Chem , vol.278 , pp. 1998-2007
    • Gowen, L.C.1    Petersen, D.N.2    Mansolf, A.L.3    Qi, H.4    Stock, J.L.5    Tkalcevic, G.T.6
  • 13
    • 69249117464 scopus 로고    scopus 로고
    • Matrix extracellular phosphoglycoprotein (MEPE) is a new bone renal hormone and vascularization modulator
    • David V., Martin A., Hedge A.M., Rowe P.S. Matrix extracellular phosphoglycoprotein (MEPE) is a new bone renal hormone and vascularization modulator. Endocrinology 2009, 150:4012-4023.
    • (2009) Endocrinology , vol.150 , pp. 4012-4023
    • David, V.1    Martin, A.2    Hedge, A.M.3    Rowe, P.S.4
  • 14
    • 41549134046 scopus 로고    scopus 로고
    • Degradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP
    • Martin A., David V., Laurence J.S., Schwarz P.M., Lafer E.M., Hedge A.M., et al. Degradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-peptide(s) are directly responsible for defective mineralization in HYP. Endocrinology 2008, 149:1757-1772.
    • (2008) Endocrinology , vol.149 , pp. 1757-1772
    • Martin, A.1    David, V.2    Laurence, J.S.3    Schwarz, P.M.4    Lafer, E.M.5    Hedge, A.M.6
  • 15
    • 10744226781 scopus 로고    scopus 로고
    • MEPE has the properties of an osteoblastic phosphatonin and minhibin
    • Rowe P.S., Kumagai Y., Gutierrez G., Garrett I.R., Blacher R., Rosen D., et al. MEPE has the properties of an osteoblastic phosphatonin and minhibin. Bone 2004, 34:303-319.
    • (2004) Bone , vol.34 , pp. 303-319
    • Rowe, P.S.1    Kumagai, Y.2    Gutierrez, G.3    Garrett, I.R.4    Blacher, R.5    Rosen, D.6
  • 16
    • 33748376254 scopus 로고    scopus 로고
    • Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin
    • Rowe P.S., Matsumoto N., Jo O.D., Shih R.N., Oconnor J., Roudier M.P., et al. Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin. Bone 2006, 39:773-786.
    • (2006) Bone , vol.39 , pp. 773-786
    • Rowe, P.S.1    Matsumoto, N.2    Jo, O.D.3    Shih, R.N.4    Oconnor, J.5    Roudier, M.P.6
  • 18
    • 52949134423 scopus 로고    scopus 로고
    • MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: an inhibition regulated by PHEX cleavage of ASARM
    • Addison W.N., Nakano Y., Loisel T., Crine P., McKee M.D. MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: an inhibition regulated by PHEX cleavage of ASARM. J Bone Miner Res 2008, 23:1638-1649.
    • (2008) J Bone Miner Res , vol.23 , pp. 1638-1649
    • Addison, W.N.1    Nakano, Y.2    Loisel, T.3    Crine, P.4    McKee, M.D.5
  • 19
    • 0033697747 scopus 로고    scopus 로고
    • Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation
    • Stevens D.A., Hasserjian R.P., Robson H., Siebler T., Shalet S.M., Williams G.R. Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation. J Bone Miner Res 2000, 15:2431-2442.
    • (2000) J Bone Miner Res , vol.15 , pp. 2431-2442
    • Stevens, D.A.1    Hasserjian, R.P.2    Robson, H.3    Siebler, T.4    Shalet, S.M.5    Williams, G.R.6
  • 20
    • 34247348274 scopus 로고    scopus 로고
    • Gradients in bone morphogenetic protein-related gene expression across the growth plate
    • Nilsson O., Parker E.A., Hegde A., Chau M., Barnes K.M., Baron J. Gradients in bone morphogenetic protein-related gene expression across the growth plate. J Endocrinol 2007, 193:75-84.
    • (2007) J Endocrinol , vol.193 , pp. 75-84
    • Nilsson, O.1    Parker, E.A.2    Hegde, A.3    Chau, M.4    Barnes, K.M.5    Baron, J.6
  • 21
    • 0027977902 scopus 로고
    • Dexamethasone increases growth hormone receptor messenger ribonucleic acid levels in liver and growth plate
    • Heinrichs C., Yanovski J.A., Roth A.H., Yu Y.M., Domene H.M., Yano K., et al. Dexamethasone increases growth hormone receptor messenger ribonucleic acid levels in liver and growth plate. Endocrinology 1994, 135:1113-1118.
    • (1994) Endocrinology , vol.135 , pp. 1113-1118
    • Heinrichs, C.1    Yanovski, J.A.2    Roth, A.H.3    Yu, Y.M.4    Domene, H.M.5    Yano, K.6
  • 22
    • 2042475388 scopus 로고    scopus 로고
    • Insulin-like growth factor-I augments chondrocyte hypertrophy and reverses glucocorticoid-mediated growth retardation in fetal mice metatarsal cultures
    • Mushtaq T., Bijman P., Ahmed S.F., Farquharson C. Insulin-like growth factor-I augments chondrocyte hypertrophy and reverses glucocorticoid-mediated growth retardation in fetal mice metatarsal cultures. Endocrinology 2004, 145:2478-2486.
    • (2004) Endocrinology , vol.145 , pp. 2478-2486
    • Mushtaq, T.1    Bijman, P.2    Ahmed, S.F.3    Farquharson, C.4
  • 23
    • 33846189394 scopus 로고    scopus 로고
    • The growth plate sparing effects of the selective glucocorticoid receptor modulator, AL-438
    • Owen H.C., Miner J.N., Ahmed S.F., Farquharson C. The growth plate sparing effects of the selective glucocorticoid receptor modulator, AL-438. Mol Cell Endocrinol 2007, 264:164-170.
    • (2007) Mol Cell Endocrinol , vol.264 , pp. 164-170
    • Owen, H.C.1    Miner, J.N.2    Ahmed, S.F.3    Farquharson, C.4
  • 24
    • 33646795652 scopus 로고    scopus 로고
    • The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines
    • MacRae V.E., Farquharson C., Ahmed S.F. The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines. J Endocrinol 2006, 189:319-328.
    • (2006) J Endocrinol , vol.189 , pp. 319-328
    • MacRae, V.E.1    Farquharson, C.2    Ahmed, S.F.3
  • 25
    • 0032867940 scopus 로고    scopus 로고
    • Inhibition of terminal chondrocyte differentiation by bone morphogenetic protein 7 (OP-1) in vitro depends on the periarticular region but is independent of parathyroid hormone-related peptide
    • Haaijman A., Karperien M., Lanske B., Hendriks J., Lowik C.W., Bronckers A.L., et al. Inhibition of terminal chondrocyte differentiation by bone morphogenetic protein 7 (OP-1) in vitro depends on the periarticular region but is independent of parathyroid hormone-related peptide. Bone 1999, 25:397-404.
    • (1999) Bone , vol.25 , pp. 397-404
    • Haaijman, A.1    Karperien, M.2    Lanske, B.3    Hendriks, J.4    Lowik, C.W.5    Bronckers, A.L.6
  • 26
    • 0030788922 scopus 로고    scopus 로고
    • Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro
    • Shukunami C., Ishizeki K., Atsumi T., Ohta Y., Suzuki F., Hiraki Y. Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro. J Bone Miner Res 1997, 12:1174-1188.
    • (1997) J Bone Miner Res , vol.12 , pp. 1174-1188
    • Shukunami, C.1    Ishizeki, K.2    Atsumi, T.3    Ohta, Y.4    Suzuki, F.5    Hiraki, Y.6
  • 27
    • 0036297353 scopus 로고    scopus 로고
    • Different effects of glucose starvation on expression and stability of VEGF mRNA isoforms in murine ovarian cancer cells
    • Zhang L., Conejo-Garcia J.R., Yang N., Huang W., Mohamed-Hadley A., Yao W., et al. Different effects of glucose starvation on expression and stability of VEGF mRNA isoforms in murine ovarian cancer cells. Biochem Biophys Res Commun 2002, 292:860-868.
    • (2002) Biochem Biophys Res Commun , vol.292 , pp. 860-868
    • Zhang, L.1    Conejo-Garcia, J.R.2    Yang, N.3    Huang, W.4    Mohamed-Hadley, A.5    Yao, W.6
  • 28
    • 77950546419 scopus 로고    scopus 로고
    • Inhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chick
    • MacRae V.E., Davey M.G., McTeir L., Narisawa S., Yadav M.C., Millan J.L., et al. Inhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chick. Bone 2010, 46:1146-1155.
    • (2010) Bone , vol.46 , pp. 1146-1155
    • MacRae, V.E.1    Davey, M.G.2    McTeir, L.3    Narisawa, S.4    Yadav, M.C.5    Millan, J.L.6
  • 29
    • 84860617035 scopus 로고    scopus 로고
    • Extracellular matrix mineralization promotes E11/gp38 glycoprotein expression and drives osteocytic differentiation
    • Prideaux M., Loveridge N., Pitsillides A.A., Farquharson C. Extracellular matrix mineralization promotes E11/gp38 glycoprotein expression and drives osteocytic differentiation. PLoS One 2012, 7:e36786.
    • (2012) PLoS One , vol.7
    • Prideaux, M.1    Loveridge, N.2    Pitsillides, A.A.3    Farquharson, C.4
  • 30
    • 70349652454 scopus 로고    scopus 로고
    • Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis
    • Saito A., Hino S., Murakami T., Kanemoto S., Kondo S., Saitoh M., et al. Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol 2009, 11:1197-1204.
    • (2009) Nat Cell Biol , vol.11 , pp. 1197-1204
    • Saito, A.1    Hino, S.2    Murakami, T.3    Kanemoto, S.4    Kondo, S.5    Saitoh, M.6
  • 31
    • 34347220127 scopus 로고    scopus 로고
    • Insulin-like growth factor-I and fibroblast growth factor, but not growth hormone, affect growth plate chondrocyte proliferation
    • Hutchison M.R., Bassett M.H., White P.C. Insulin-like growth factor-I and fibroblast growth factor, but not growth hormone, affect growth plate chondrocyte proliferation. Endocrinology 2007, 148:3122-3130.
    • (2007) Endocrinology , vol.148 , pp. 3122-3130
    • Hutchison, M.R.1    Bassett, M.H.2    White, P.C.3
  • 32
    • 73549099987 scopus 로고    scopus 로고
    • Septoclast deficiency accompanies postnatal growth plate chondrodysplasia in the toothless (tl) osteopetrotic, colony-stimulating factor-1 (CSF-1)-deficient rat and is partially responsive to CSF-1 injections
    • Gartland A., Mason-Savas A., Yang M., MacKay C.A., Birnbaum M.J., Odgren P.R. Septoclast deficiency accompanies postnatal growth plate chondrodysplasia in the toothless (tl) osteopetrotic, colony-stimulating factor-1 (CSF-1)-deficient rat and is partially responsive to CSF-1 injections. Am J Pathol 2009, 175:2668-2675.
    • (2009) Am J Pathol , vol.175 , pp. 2668-2675
    • Gartland, A.1    Mason-Savas, A.2    Yang, M.3    MacKay, C.A.4    Birnbaum, M.J.5    Odgren, P.R.6
  • 33
    • 0028942799 scopus 로고
    • The septoclast, a cathepsin B-rich cell involved in the resorption of growth plate cartilage
    • Lee E.R., Lamplugh L., Shepard N.L., Mort J.S. The septoclast, a cathepsin B-rich cell involved in the resorption of growth plate cartilage. J Histochem Cytochem 1995, 43:525-536.
    • (1995) J Histochem Cytochem , vol.43 , pp. 525-536
    • Lee, E.R.1    Lamplugh, L.2    Shepard, N.L.3    Mort, J.S.4
  • 35
    • 0014832235 scopus 로고
    • The loss of phenotypic traits by differentiated cells in vitro. VII. Effects of 5-bromodeoxyuridine and prolonged culturing on fine structure of chondrocytes
    • Anderson H.C., Chacko S., Abbott J., Holtzer H. The loss of phenotypic traits by differentiated cells in vitro. VII. Effects of 5-bromodeoxyuridine and prolonged culturing on fine structure of chondrocytes. Am J Pathol 1970, 60:289-312.
    • (1970) Am J Pathol , vol.60 , pp. 289-312
    • Anderson, H.C.1    Chacko, S.2    Abbott, J.3    Holtzer, H.4
  • 36
    • 0014558358 scopus 로고
    • The loss of phenotypic traits by differentiated cells. VI. Behavior of the progeny of a single chondrocyte
    • Chacko S., Abbott J., Holtzer S., Holtzer H. The loss of phenotypic traits by differentiated cells. VI. Behavior of the progeny of a single chondrocyte. J Exp Med 1969, 130:417-442.
    • (1969) J Exp Med , vol.130 , pp. 417-442
    • Chacko, S.1    Abbott, J.2    Holtzer, S.3    Holtzer, H.4
  • 37
    • 0014133802 scopus 로고
    • The loss of phenotypic traits by differentiated cells. IV. Changes in polysaccharides produced by dividing chondrocytes
    • Nameroff M., Holtzer H. The loss of phenotypic traits by differentiated cells. IV. Changes in polysaccharides produced by dividing chondrocytes. Dev Biol 1967, 16:250-281.
    • (1967) Dev Biol , vol.16 , pp. 250-281
    • Nameroff, M.1    Holtzer, H.2
  • 38
    • 0013883741 scopus 로고
    • The loss of phenotypic traits by differentiated cells. 3. The reversible behavior of chondrocytes in primary cultures
    • Abbott J., Holtzer H. The loss of phenotypic traits by differentiated cells. 3. The reversible behavior of chondrocytes in primary cultures. J Cell Biol 1966, 28:473-487.
    • (1966) J Cell Biol , vol.28 , pp. 473-487
    • Abbott, J.1    Holtzer, H.2
  • 39
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • Gerber H.P., Vu T.H., Ryan A.M., Kowalski J., Werb Z., Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 1999, 5:623-628.
    • (1999) Nat Med , vol.5 , pp. 623-628
    • Gerber, H.P.1    Vu, T.H.2    Ryan, A.M.3    Kowalski, J.4    Werb, Z.5    Ferrara, N.6
  • 40
    • 3042593389 scopus 로고    scopus 로고
    • Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3)
    • Zijlstra A., Aimes R.T., Zhu D., Regazzoni K., Kupriyanova T., Seandel M., et al. Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3). J Biol Chem 2004, 279:27633-27645.
    • (2004) J Biol Chem , vol.279 , pp. 27633-27645
    • Zijlstra, A.1    Aimes, R.T.2    Zhu, D.3    Regazzoni, K.4    Kupriyanova, T.5    Seandel, M.6
  • 41
    • 0141514450 scopus 로고    scopus 로고
    • Inhibition of growth plate angiogenesis and endochondral ossification with diminished expression of MMP-13 in hypertrophic chondrocytes in FGF-2-treated rats
    • Nagai H., Aoki M. Inhibition of growth plate angiogenesis and endochondral ossification with diminished expression of MMP-13 in hypertrophic chondrocytes in FGF-2-treated rats. J Bone Miner Metab 2002, 20:142-147.
    • (2002) J Bone Miner Metab , vol.20 , pp. 142-147
    • Nagai, H.1    Aoki, M.2
  • 42
    • 1242316272 scopus 로고    scopus 로고
    • Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient mice
    • Anderson H.C., Sipe J.B., Hessle L., Dhanyamraju R., Atti E., Camacho N.P., et al. Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient mice. Am J Pathol 2004, 164:841-847.
    • (2004) Am J Pathol , vol.164 , pp. 841-847
    • Anderson, H.C.1    Sipe, J.B.2    Hessle, L.3    Dhanyamraju, R.4    Atti, E.5    Camacho, N.P.6
  • 43
    • 0037047051 scopus 로고    scopus 로고
    • Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization
    • Hessle L., Johnson K.A., Anderson H.C., Narisawa S., Sali A., Goding J.W., et al. Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization. Proc Natl Acad Sci U S A 2002, 99:9445-9449.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9445-9449
    • Hessle, L.1    Johnson, K.A.2    Anderson, H.C.3    Narisawa, S.4    Sali, A.5    Goding, J.W.6
  • 44
    • 16244369497 scopus 로고    scopus 로고
    • Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice
    • Johnson K., Polewski M., van E.D., Terkeltaub R. Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice. Arterioscler Thromb Vasc Biol 2005, 25:686-691.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 686-691
    • Johnson, K.1    Polewski, M.2    van, E.D.3    Terkeltaub, R.4
  • 45
    • 0035041718 scopus 로고    scopus 로고
    • Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia
    • Nurnberg P., Thiele H., Chandler D., Hohne W., Cunningham M.L., Ritter H., et al. Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia. Nat Genet 2001, 28:37-41.
    • (2001) Nat Genet , vol.28 , pp. 37-41
    • Nurnberg, P.1    Thiele, H.2    Chandler, D.3    Hohne, W.4    Cunningham, M.L.5    Ritter, H.6
  • 46
    • 0036089277 scopus 로고    scopus 로고
    • Developmental and TGF-beta-mediated regulation of Ank mRNA expression in cartilage and bone
    • Sohn P., Crowley M., Slattery E., Serra R. Developmental and TGF-beta-mediated regulation of Ank mRNA expression in cartilage and bone. Osteoarthritis Cartilage 2002, 10:482-490.
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 482-490
    • Sohn, P.1    Crowley, M.2    Slattery, E.3    Serra, R.4
  • 47
    • 11244352700 scopus 로고    scopus 로고
    • The wrickkened pathways of FGF23, MEPE and PHEX
    • Rowe P.S. The wrickkened pathways of FGF23, MEPE and PHEX. Crit Rev Oral Biol Med 2004, 15:264-281.
    • (2004) Crit Rev Oral Biol Med , vol.15 , pp. 264-281
    • Rowe, P.S.1
  • 48
    • 0033763097 scopus 로고    scopus 로고
    • Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23
    • Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23. Nat Genet 2000, 26:345-348.
    • (2000) Nat Genet , vol.26 , pp. 345-348
  • 49
    • 9644303231 scopus 로고    scopus 로고
    • Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice
    • Sitara D., Razzaque M.S., Hesse M., Yoganathan S., Taguchi T., Erben R.G., et al. Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice. Matrix Biol 2004, 23:421-432.
    • (2004) Matrix Biol , vol.23 , pp. 421-432
    • Sitara, D.1    Razzaque, M.S.2    Hesse, M.3    Yoganathan, S.4    Taguchi, T.5    Erben, R.G.6
  • 51
    • 18144378440 scopus 로고    scopus 로고
    • FGF23 and disorders of phosphate homeostasis
    • Yu X., White K.E. FGF23 and disorders of phosphate homeostasis. Cytokine Growth Factor Rev 2005, 16:221-232.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 221-232
    • Yu, X.1    White, K.E.2
  • 52
    • 4644312298 scopus 로고    scopus 로고
    • Expression of SIBLINGs and their partner MMPs in salivary glands
    • Ogbureke K.U., Fisher L.W. Expression of SIBLINGs and their partner MMPs in salivary glands. J Dent Res 2004, 83:664-670.
    • (2004) J Dent Res , vol.83 , pp. 664-670
    • Ogbureke, K.U.1    Fisher, L.W.2
  • 53
    • 77957288774 scopus 로고    scopus 로고
    • Abnormal presence of the matrix extracellular phosphoglycoprotein-derived acidic serine- and aspartate-rich motif peptide in human hypophosphatemic dentin
    • Boukpessi T., Gaucher C., Leger T., Salmon B., Le F.J., Willig C., et al. Abnormal presence of the matrix extracellular phosphoglycoprotein-derived acidic serine- and aspartate-rich motif peptide in human hypophosphatemic dentin. Am J Pathol 2010, 177:803-812.
    • (2010) Am J Pathol , vol.177 , pp. 803-812
    • Boukpessi, T.1    Gaucher, C.2    Leger, T.3    Salmon, B.4    Le, F.J.5    Willig, C.6
  • 54
    • 11244270453 scopus 로고    scopus 로고
    • Serum MEPE-ASARM-peptides are elevated in X-linked rickets (HYP): implications for phosphaturia and rickets
    • Bresler D., Bruder J., Mohnike K., Fraser W.D., Rowe P.S. Serum MEPE-ASARM-peptides are elevated in X-linked rickets (HYP): implications for phosphaturia and rickets. J Endocrinol 2004, 183:R1-R9.
    • (2004) J Endocrinol , vol.183
    • Bresler, D.1    Bruder, J.2    Mohnike, K.3    Fraser, W.D.4    Rowe, P.S.5
  • 55
    • 79954637641 scopus 로고    scopus 로고
    • Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism
    • Atkins G.J., Rowe P.S., Lim H.P., Welldon K.J., Ormsby R., Wijenayaka A.R., et al. Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism. J Bone Miner Res 2011, 26:1425-1436.
    • (2011) J Bone Miner Res , vol.26 , pp. 1425-1436
    • Atkins, G.J.1    Rowe, P.S.2    Lim, H.P.3    Welldon, K.J.4    Ormsby, R.5    Wijenayaka, A.R.6
  • 56
    • 0141560730 scopus 로고    scopus 로고
    • Matrix vesicles and calcification
    • Anderson H.C. Matrix vesicles and calcification. Curr Rheumatol Rep 2003, 5:222-226.
    • (2003) Curr Rheumatol Rep , vol.5 , pp. 222-226
    • Anderson, H.C.1
  • 57
    • 34447538396 scopus 로고    scopus 로고
    • Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity
    • Addison W.N., Azari F., Sorensen E.S., Kaartinen M.T., McKee M.D. Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity. J Biol Chem 2007, 282:15872-15883.
    • (2007) J Biol Chem , vol.282 , pp. 15872-15883
    • Addison, W.N.1    Azari, F.2    Sorensen, E.S.3    Kaartinen, M.T.4    McKee, M.D.5
  • 58
    • 33748964143 scopus 로고    scopus 로고
    • Site-specific in vivo calcification and osteogenesis stimulated by bone sialoprotein
    • Wang J., Zhou H.Y., Salih E., Xu L., Wunderlich L., Gu X., et al. Site-specific in vivo calcification and osteogenesis stimulated by bone sialoprotein. Calcif Tissue Int 2006, 79:179-189.
    • (2006) Calcif Tissue Int , vol.79 , pp. 179-189
    • Wang, J.1    Zhou, H.Y.2    Salih, E.3    Xu, L.4    Wunderlich, L.5    Gu, X.6
  • 59
    • 79251482785 scopus 로고    scopus 로고
    • Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcification
    • Yadav M.C., Simao A.M., Narisawa S., Huesa C., McKee M.D., Farquharson C., et al. Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcification. J Bone Miner Res 2011, 26:286-297.
    • (2011) J Bone Miner Res , vol.26 , pp. 286-297
    • Yadav, M.C.1    Simao, A.M.2    Narisawa, S.3    Huesa, C.4    McKee, M.D.5    Farquharson, C.6
  • 60
    • 79954593780 scopus 로고    scopus 로고
    • PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures
    • Huesa C., Yadav M.C., Finnila M.A., Goodyear S.R., Robins S.P., Tanner K.E., et al. PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures. Bone 2011, 48:1066-1074.
    • (2011) Bone , vol.48 , pp. 1066-1074
    • Huesa, C.1    Yadav, M.C.2    Finnila, M.A.3    Goodyear, S.R.4    Robins, S.P.5    Tanner, K.E.6
  • 61
    • 49149124472 scopus 로고    scopus 로고
    • ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion
    • Sprowson A.P., McCaskie A.W., Birch M.A. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res 2008, 26:1256-1262.
    • (2008) J Orthop Res , vol.26 , pp. 1256-1262
    • Sprowson, A.P.1    McCaskie, A.W.2    Birch, M.A.3
  • 62
    • 2942748650 scopus 로고    scopus 로고
    • A synthetic peptide fragment of human MEPE stimulates new bone formation in vitro and in vivo
    • Hayashibara T., Hiraga T., Yi B., Nomizu M., Kumagai Y., Nishimura R., et al. A synthetic peptide fragment of human MEPE stimulates new bone formation in vitro and in vivo. J Bone Miner Res 2004, 19:455-462.
    • (2004) J Bone Miner Res , vol.19 , pp. 455-462
    • Hayashibara, T.1    Hiraga, T.2    Yi, B.3    Nomizu, M.4    Kumagai, Y.5    Nishimura, R.6
  • 64
    • 84863314939 scopus 로고    scopus 로고
    • The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambled
    • Rowe P.S. The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambled. Cell Biochem Funct 2012, 30(5):355-375.
    • (2012) Cell Biochem Funct , vol.30 , Issue.5 , pp. 355-375
    • Rowe, P.S.1
  • 65
    • 12344250943 scopus 로고    scopus 로고
    • Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP)
    • Rowe P.S., Garrett I.R., Schwarz P.M., Carnes D.L., Lafer E.M., Mundy G.R., et al. Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP). Bone 2005, 36:33-46.
    • (2005) Bone , vol.36 , pp. 33-46
    • Rowe, P.S.1    Garrett, I.R.2    Schwarz, P.M.3    Carnes, D.L.4    Lafer, E.M.5    Mundy, G.R.6
  • 66
    • 33947385485 scopus 로고    scopus 로고
    • Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity
    • Liu S., Rowe P.S., Vierthaler L., Zhou J., Quarles L.D. Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity. J Endocrinol 2007, 192:261-267.
    • (2007) J Endocrinol , vol.192 , pp. 261-267
    • Liu, S.1    Rowe, P.S.2    Vierthaler, L.3    Zhou, J.4    Quarles, L.D.5
  • 67
    • 0036339867 scopus 로고    scopus 로고
    • Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis
    • Zelzer E., McLean W., Ng Y.S., Fukai N., Reginato A.M., Lovejoy S., et al. Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development 2002, 129:1893-1904.
    • (2002) Development , vol.129 , pp. 1893-1904
    • Zelzer, E.1    McLean, W.2    Ng, Y.S.3    Fukai, N.4    Reginato, A.M.5    Lovejoy, S.6
  • 68
    • 19944426775 scopus 로고    scopus 로고
    • Altered endochondral bone development in matrix metalloproteinase 13-deficient mice
    • Stickens D., Behonick D.J., Ortega N., Heyer B., Hartenstein B., Yu Y., et al. Altered endochondral bone development in matrix metalloproteinase 13-deficient mice. Development 2004, 131:5883-5895.
    • (2004) Development , vol.131 , pp. 5883-5895
    • Stickens, D.1    Behonick, D.J.2    Ortega, N.3    Heyer, B.4    Hartenstein, B.5    Yu, Y.6
  • 69
    • 79952164899 scopus 로고    scopus 로고
    • Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation
    • Pirotte S., Lamour V., Lambert V., varez Gonzalez M.L., Ormenese S., Noel A., et al. Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation. Blood 2011, 117:2515-2526.
    • (2011) Blood , vol.117 , pp. 2515-2526
    • Pirotte, S.1    Lamour, V.2    Lambert, V.3    varez Gonzalez, M.L.4    Ormenese, S.5    Noel, A.6


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