PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures

Bone

Volumn 48, Issue 5, 2011, Pages 1066-1074

  Huesa, Carmen ^a   Yadav, Manisha C ^b   Finnilä, Mikko A J ^c,d   Goodyear, Simon R ^e   Robins, Simon P ^f   Tanner, K Elizabeth ^c   Aspden, Richard M ^e   Millán, José Luis ^b   Farquharson, Colin ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b BURNHAM INSTITUTE   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF OULU   (Finland)

^e UNIVERSITY OF ABERDEEN   (United Kingdom)

^f ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Biomineralization; Bone quality; Hypomineralization; Mechanical and material properties; Phospho1

Indexed keywords

AMINO TERMINAL PROPEPTIDE; CARBONIC ACID; CARBOXY TERMINAL TELOPEPTIDE; COLLAGEN; DEOXYPYRIDINOLINE; DIHYDROXYLYSINONORLEUCINE; HYDROXYLYSINONORLEUCINE; LEUCINE; LYSYL HYDROXYLASE 1; OXYGENASE; PEPTIDE; PHOSPHATASE; PROTEIN PHOSPHO1; PYRIDINOLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE BOWING; BONE MINERAL; BONE MINERALIZATION; BONE REMODELING; BONE STRENGTH; BONE STRESS; CONTROLLED STUDY; ENZYME ACTIVITY; FRACTURE; GENE; LONG BONE; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; PHENOTYPE; PHOSPHO1 GENE; TIBIA; WEIGHT BEARING; WILD TYPE; YOUNG MODULUS;

ANIMALS; BIOLOGICAL MARKERS; BIOMECHANICS; BONE REMODELING; CALCIFICATION, PHYSIOLOGIC; COLLAGEN; ELASTICITY; FEMUR; FRACTURES, SPONTANEOUS; HARDNESS; MICE; PHOSPHORIC MONOESTER HYDROLASES; TIBIA; VISCOSITY;

EID: 79954593780     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.01.010     Document Type: Article

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