Inhibition of growth plate angiogenesis and endochondral ossification with diminished expression of MMP-13 in hypertrophic chondrocytes in FGF-2-treated rats

Journal of Bone and Mineral Metabolism

Volumn 20, Issue 3, 2002, Pages 142-147

  Nagai, Hirofumi ^a   Aoki, Masami ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Angiogenesis; Endochondral bone formation; FGF 2; MMP 13; Rat

Indexed keywords

COLLAGENASE 3; FIBROBLAST GROWTH FACTOR 2; COLLAGEN TYPE 10; COLLAGENASE; CYCLINE; MMP13 PROTEIN, RAT;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE; CARTILAGE CELL; CARTILAGE MATRIX; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; FEMALE; GROWTH PLATE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; TRABECULAR BONE; ANIMAL; BIOSYNTHESIS; BONE DEVELOPMENT; CELL DIVISION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; METHODOLOGY; PHYSIOLOGY; STAINING; TIBIA; VASCULARIZATION; WISTAR RAT;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CHONDROCYTES; COLLAGEN TYPE X; COLLAGENASES; FEMALE; FIBROBLAST GROWTH FACTOR 2; GROWTH PLATE; IMMUNOHISTOCHEMISTRY; MATRIX METALLOPROTEINASE 13; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOGENESIS; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, WISTAR; STAINING AND LABELING; TIBIA;

EID: 0141514450     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007740200020     Document Type: Article

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