-
1
-
-
72149119542
-
How the fanconi anemia pathway guards the genome
-
Moldovan GL, D'Andrea AD. How the fanconi anemia pathway guards the genome. Annu Rev Genet. 2009;43:223-249.
-
(2009)
Annu Rev Genet.
, vol.43
, pp. 223-249
-
-
Moldovan, G.L.1
D'Andrea, A.D.2
-
2
-
-
79251624412
-
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia
-
Crossan GP, van der Weyden L, Rosado IV, et al. Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia. Nat Genet. 2011;43(2):147-152.
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 147-152
-
-
Crossan, G.P.1
Van Der Weyden, L.2
Rosado, I.V.3
-
3
-
-
79251611165
-
Mutations of the SLX4 gene in Fanconi anemia
-
Kim Y, Lach FP, Desetty R, Hanenberg H, Auerbach AD, Smogorzewska A. Mutations of the SLX4 gene in Fanconi anemia. Nat Genet. 2011; 43(2):142-146.
-
(2011)
Nat Genet.
, vol.43
, Issue.2
, pp. 142-146
-
-
Kim, Y.1
Lach, F.P.2
Desetty, R.3
Hanenberg, H.4
Auerbach, A.D.5
Smogorzewska, A.6
-
4
-
-
79251632658
-
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype
-
Stoepker C, Hain K, Schuster B, et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43(2):138-141.
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 138-141
-
-
Stoepker, C.1
Hain, K.2
Schuster, B.3
-
5
-
-
77951720395
-
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
-
Meindl A, Hellebrand H, Wiek C, et al. Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat Genet. 2010;42(5):410-414.
-
(2010)
Nat Genet.
, vol.42
, Issue.5
, pp. 410-414
-
-
Meindl, A.1
Hellebrand, H.2
Wiek, C.3
-
6
-
-
77951747926
-
Mutation of the RAD51C gene in a Fanconi anemia-like disorder
-
Vaz F, Hanenberg H, Schuster B, et al. Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nat Genet. 2010;42(5):406-409.
-
(2010)
Nat Genet.
, vol.42
, Issue.5
, pp. 406-409
-
-
Vaz, F.1
Hanenberg, H.2
Schuster, B.3
-
7
-
-
77949267134
-
The structure of the catalytic subunit FANCL of the Fanconi anemia core complex
-
Cole AR, Lewis LP, Walden H. The structure of the catalytic subunit FANCL of the Fanconi anemia core complex. Nat Struct Mol Biol. 2010; 17(3):294-298.
-
(2010)
Nat Struct Mol Biol.
, vol.17
, Issue.3
, pp. 294-298
-
-
Cole, A.R.1
Lewis, L.P.2
Walden, H.3
-
8
-
-
57749112131
-
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI
-
Alpi AF, Pace PE, Babu MM, Patel KJ. Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. Mol Cell. 2008;32(6):767-777.
-
(2008)
Mol Cell.
, vol.32
, Issue.6
, pp. 767-777
-
-
Alpi, A.F.1
Pace, P.E.2
Babu, M.M.3
Patel, K.J.4
-
9
-
-
2942664480
-
FANCL replaces BRCA1 as the likely ubiquitin ligase responsible for FANCD2 monoubiquitination
-
Meetei AR, Yan Z, Wang W. FANCL replaces BRCA1 as the likely ubiquitin ligase responsible for FANCD2 monoubiquitination. Cell Cycle. 2004;3(2):179-181. (Pubitemid 40268694)
-
(2004)
Cell Cycle
, vol.3
, Issue.2
, pp. 179-181
-
-
Meetei, A.R.1
Yan, Z.2
Wang, W.3
-
10
-
-
33847634432
-
A requirement of FancL and FancD2 monoubiquitination in DNA repair
-
DOI 10.1111/j.1365-2443.2007.01054.x
-
Seki S, Ohzeki M, Uchida A, et al. A requirement of FancL and FancD2 monoubiquitination in DNA repair. Genes Cells. 2007;12(3):299-310. (Pubitemid 46359585)
-
(2007)
Genes to Cells
, vol.12
, Issue.3
, pp. 299-310
-
-
Seki, S.1
Ohzeki, M.2
Uchida, A.3
Hirano, S.4
Matsushita, N.5
Kitao, H.6
Oda, T.7
Yamashita, T.8
Kashihara, N.9
Tsubahara, A.10
Takata, M.11
Ishiai, M.12
-
11
-
-
0035881864
-
FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity
-
DOI 10.1093/emboj/20.16.4478
-
Pang Q, Keeble W, Christianson TA, Faulkner GR, Bagby GC. FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/ TNF-alpha-mediated cytotoxicity. EMBO J. 2001;20(16):4478-4489. (Pubitemid 32772042)
-
(2001)
EMBO Journal
, vol.20
, Issue.16
, pp. 4478-4489
-
-
Pang, Q.1
Keeble, W.2
Christianson, T.A.3
Faulkner, G.R.4
Bagby, G.C.5
-
12
-
-
52649092305
-
HES1 is a novel interactor of the Fanconi anemia core complex
-
Tremblay CS, Huang FF, Habi O, et al. HES1 is a novel interactor of the Fanconi anemia core complex. Blood. 2008;112(5):2062-2070.
-
(2008)
Blood.
, vol.112
, Issue.5
, pp. 2062-2070
-
-
Tremblay, C.S.1
Huang, F.F.2
Habi, O.3
-
13
-
-
73949118736
-
TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells
-
Vanderwerf SM, Svahn J, Olson S, et al. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. Blood. 2009;114(26): 5290-5298.
-
(2009)
Blood.
, vol.114
, Issue.26
, pp. 5290-5298
-
-
Vanderwerf, S.M.1
Svahn, J.2
Olson, S.3
-
14
-
-
6344244517
-
The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR)
-
DOI 10.1074/jbc.M403884200
-
Zhang X, Li J, Sejas DP, Rathbun KR, Bagby GC, Pang Q. The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR). J Biol Chem. 2004;279(42):43910-43919. (Pubitemid 39390699)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.42
, pp. 43910-43919
-
-
Zhang, X.1
Li, J.2
Sejas, D.P.3
Rathbun, K.R.4
Bagby, G.C.5
Pang, Q.6
-
15
-
-
79956033992
-
The stem cell fitness landscape and pathways of molecular leukemogenesis
-
Bagby GC, Fleischman AG. The stem cell fitness landscape and pathways of molecular leukemogenesis. Front Biosci (Schol Ed). 2011;3:487-500.
-
(2011)
Front Biosci (Schol Ed)
, vol.3
, pp. 487-500
-
-
Bagby, G.C.1
Fleischman, A.G.2
-
16
-
-
82955235602
-
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway
-
Rosado IV, Langevin F, Crossan GP, Takata M, Patel KJ. Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway. Nat Struct Mol Biol. 2011;18(12):1432-1434.
-
(2011)
Nat Struct Mol Biol.
, vol.18
, Issue.12
, pp. 1432-1434
-
-
Rosado, I.V.1
Langevin, F.2
Crossan, G.P.3
Takata, M.4
Patel, K.J.5
-
17
-
-
0033168321
-
Loss of FancC function results in decreased hematopoietic stem cell repopulating ability
-
Haneline LS, Gobbett TA, Ramani R, et al. Loss of FancC function results in decreased hematopoietic stem cell repopulating ability. Blood. 1999; 94(1):1-8. (Pubitemid 29300127)
-
(1999)
Blood
, vol.94
, Issue.1
, pp. 1-8
-
-
Haneline, L.S.1
Gobbett, T.A.2
Ramani, R.3
Carreau, M.4
Buchwald, M.5
Yoder, M.C.6
Clapp, D.W.7
-
18
-
-
33845993292
-
Stem cell collection and gene transfer in fanconi anemia
-
DOI 10.1038/sj.mt.6300033, PII 6300033
-
Kelly PF, Radtke S, von Kalle C, et al. Stem cell collection and gene transfer in Fanconi anemia. Mol Ther. 2007;15(1):211-219. (Pubitemid 46043667)
-
(2007)
Molecular Therapy
, vol.15
, Issue.1
, pp. 211-219
-
-
Kelly, P.F.1
Radtke, S.2
Von, K.C.3
Balcik, B.4
Bohn, K.5
Mueller, R.6
Schuesler, T.7
Haren, M.8
Reeves, L.9
Cancelas, J.A.10
Leemhuis, T.11
Harris, R.12
Auerbach, A.D.13
Smith, F.O.14
Davies, S.M.15
Williams, D.A.16
-
19
-
-
0037108308
-
Hematopoietic progenitor cell harvest and functionality in Fanconi anemia patients
-
Larghero J, Marolleau JP, Soulier J, et al. Hematopoietic progenitor cell harvest and functionality in Fanconi anemia patients. Blood. 2002;100(8): 3051.
-
(2002)
Blood.
, vol.100
, Issue.8
, pp. 3051
-
-
Larghero, J.1
Marolleau, J.P.2
Soulier, J.3
-
20
-
-
0033588822
-
Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC)
-
DOI 10.1089/10430349950016988
-
Liu JM, Kim S, Read EJ, et al. Engraftment of hematopoietic progenitor cells transduced with the Fanconi anemia group C gene (FANCC). Hum Gene Ther. 1999;10(14):2337-2346. (Pubitemid 29459844)
-
(1999)
Human Gene Therapy
, vol.10
, Issue.14
, pp. 2337-2346
-
-
Liu, J.M.1
Kim, S.2
Read, E.J.3
Futaki, M.4
Dokal, I.5
Carter, C.S.6
Leitman, S.F.7
Pensiero, M.8
Young, N.S.9
Walsh, C.E.10
-
21
-
-
67650095306
-
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
-
Raya A, Rodriguez-Piza I, Guenechea G, et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature. 2009;460(7251):53-59.
-
(2009)
Nature.
, vol.460
, Issue.7251
, pp. 53-59
-
-
Raya, A.1
Rodriguez-Piza, I.2
Guenechea, G.3
-
22
-
-
77951740623
-
Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage
-
Tulpule A, Lensch MW, Miller JD, et al. Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage. Blood. 2010; 115(17):3453-3462.
-
(2010)
Blood.
, vol.115
, Issue.17
, pp. 3453-3462
-
-
Tulpule, A.1
Lensch, M.W.2
Miller, J.D.3
-
23
-
-
52649129160
-
Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A
-
Zhang X, Shang X, Guo F, et al. Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A. Blood. 2008;112(5):1683-1686.
-
(2008)
Blood.
, vol.112
, Issue.5
, pp. 1683-1686
-
-
Zhang, X.1
Shang, X.2
Guo, F.3
-
24
-
-
36048948219
-
TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells
-
DOI 10.1172/JCI31772
-
Li J, Sejas DP, Zhang X, et al. TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. J Clin Invest. 2007;117(11):3283-3295. (Pubitemid 350096985)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3283-3295
-
-
Li, J.1
Sejas, D.P.2
Zhang, X.3
Qiu, Y.4
Nattamai, K.J.5
Rani, R.6
Rathbun, K.R.7
Geiger, H.8
Williams, D.A.9
Bagby, G.C.10
Pang, Q.11
-
25
-
-
34247127084
-
Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient mice
-
Sejas DP, Rani R, Qiu Y, et al. Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient mice. J Immunol. 2007;178(8):5277-5287. (Pubitemid 46595313)
-
(2007)
Journal of Immunology
, vol.178
, Issue.8
, pp. 5277-5287
-
-
Sejas, D.P.1
Rani, R.2
Qiu, Y.3
Zhang, X.4
Fagerlie, S.R.5
Nakano, H.6
Williams, D.A.7
Pang, Q.8
-
26
-
-
34249671829
-
Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence
-
DOI 10.1242/jcs.003152
-
Zhang X, Sejas DP, Qiu Y, Williams DA, Pang Q. Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence. J Cell Sci. 2007;120(Pt 9):1572-1583. (Pubitemid 46831787)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.9
, pp. 1572-1583
-
-
Zhang, X.1
Sejas, D.P.2
Qiu, Y.3
Williams, D.A.4
Pang, Q.5
-
27
-
-
39749178390
-
Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo
-
DOI 10.1016/j.stem.2008.01.003, PII S1934590908000040
-
Fleming HE, Janzen V, Lo Celso C, et al. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell. 2008;2(3): 274-283. (Pubitemid 351298592)
-
(2008)
Cell Stem Cell
, vol.2
, Issue.3
, pp. 274-283
-
-
Fleming, H.E.1
Janzen, V.2
Lo, C.C.3
Guo, J.4
Leahy, K.M.5
Kronenberg, H.M.6
Scadden, D.T.7
-
28
-
-
60249101799
-
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation
-
Luis TC, Weerkamp F, Naber BA, et al. Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation. Blood. 2009;113(3): 546-554.
-
(2009)
Blood.
, vol.113
, Issue.3
, pp. 546-554
-
-
Luis, T.C.1
Weerkamp, F.2
Naber, B.A.3
-
29
-
-
36649002031
-
Loss of beta-Catenin Impairs the Renewal of Normal and CML Stem Cells In Vivo
-
DOI 10.1016/j.ccr.2007.11.003, PII S1535610807003340
-
Zhao C, Blum J, Chen A, et al. Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell. 2007;12(6):528-541. (Pubitemid 350199070)
-
(2007)
Cancer Cell
, vol.12
, Issue.6
, pp. 528-541
-
-
Zhao, C.1
Blum, J.2
Chen, A.3
Kwon, H.Y.4
Jung, S.H.5
Cook, J.M.6
Lagoo, A.7
Reya, T.8
-
30
-
-
77957005350
-
The various roles of ubiquitin in Wnt pathway regulation
-
Tauriello DV, Maurice MM. The various roles of ubiquitin in Wnt pathway regulation. Cell Cycle. 2010;9(18):3700-3709.
-
(2010)
Cell Cycle.
, vol.9
, Issue.18
, pp. 3700-3709
-
-
Tauriello, D.V.1
Maurice, M.M.2
-
31
-
-
40949135212
-
Rad6B is a positive regulator of beta-catenin stabilization
-
DOI 10.1158/0008-5472.CAN-07-2111
-
Shekhar MP, Gerard B, Pauley RJ, Williams BO, Tait L. Rad6B is a positive regulator of beta-catenin stabilization. Cancer Res. 2008;68(6): 1741-1750. (Pubitemid 351416559)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1741-1750
-
-
Shekhar, M.P.V.1
Gerard, B.2
Pauley, R.J.3
Williams, B.O.4
Tait, L.5
-
32
-
-
79551675617
-
The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin
-
Hay-Koren A, Caspi M, Zilberberg A, Rosin-Arbesfeld R. The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin. Mol Biol Cell. 2011;22(3):399-411.
-
(2011)
Mol Biol Cell
, vol.22
, Issue.3
, pp. 399-411
-
-
Hay-Koren, A.1
Caspi, M.2
Zilberberg, A.3
Rosin-Arbesfeld, R.4
-
33
-
-
77957196995
-
Human FANCC is hypomorphic in murine Fancc-deficient cells
-
Hays LE, Keeble WW, Yates JE, et al. Human FANCC is hypomorphic in murine Fancc-deficient cells. Blood. 2010;116(12):2057-2060.
-
(2010)
Blood.
, vol.116
, Issue.12
, pp. 2057-2060
-
-
Hays, L.E.1
Keeble, W.W.2
Yates, J.E.3
-
34
-
-
0344373791
-
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements
-
DOI 10.1016/S0960-9822(03)00240-9
-
Veeman MT, Slusarski DC, Kaykas A, Louie SH, Moon RT. Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements. Curr Biol. 2003;13(8):680-685. (Pubitemid 36453318)
-
(2003)
Current Biology
, vol.13
, Issue.8
, pp. 680-685
-
-
Veeman, M.T.1
Slusarski, D.C.2
Kaykas, A.3
Louie, S.H.4
Moon, R.T.5
-
35
-
-
0030695339
-
Characterization of NEDD8, a developmentally down-regulated ubiquitin- like protein
-
DOI 10.1074/jbc.272.45.28557
-
Kamitani T, Kito K, Nguyen HP, Yeh ET. Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein. J Biol Chem. 1997;272(45):28557-28562. (Pubitemid 27517807)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.45
, pp. 28557-28562
-
-
Kamitani, T.1
Kito, K.2
Nguyen, H.P.3
Yeh, E.T.H.4
-
36
-
-
20044386298
-
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: Implications for lewy body formation
-
DOI 10.1523/JNEUROSCI.4474-04.2005
-
Lim KL, Chew KC, Tan JM, et al. Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation. J Neurosci. 2005;25(8):2002-2009. (Pubitemid 40289405)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.8
, pp. 2002-2009
-
-
Kah, L.L.1
Chew, K.C.M.2
Tan, J.M.M.3
Wang, C.4
Chung, K.K.K.5
Zhang, Y.6
Tanaka, Y.7
Smith, W.8
Engelender, S.9
Ross, C.A.10
Dawson, V.L.11
Dawson, T.M.12
-
37
-
-
73949094851
-
Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infection
-
Livingston CM, Ifrim MF, Cowan AE, Weller SK. Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infection. PLoS Pathog. 2009;5(10):e1000619.
-
(2009)
PLoS Pathog.
, vol.5
, Issue.10
-
-
Livingston, C.M.1
Ifrim, M.F.2
Cowan, A.E.3
Weller, S.K.4
-
38
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29(9):e45.
-
(2001)
Nucleic Acids Res
, vol.29
, Issue.9
-
-
Pfaffl, M.W.1
-
39
-
-
0038712560
-
Convergence of Wnt signaling and steroidogenic factor-1 (SF-1) on transcription of the rat inhibin alpha gene
-
DOI 10.1074/jbc.M212677200
-
Gummow BM, Winnay JN, Hammer GD. Convergence of Wnt signaling and steroidogenic factor-1 (SF-1) on transcription of the rat inhibin alpha gene. J Biol Chem. 2003;278(29):26572-26579. (Pubitemid 36876801)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.29
, pp. 26572-26579
-
-
Gummow, B.M.1
Winnay, J.N.2
Hammer, G.D.3
-
40
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
DOI 10.1038/nm979
-
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med. 2004;10(1):55-63. (Pubitemid 38524699)
-
(2004)
Nature Medicine
, vol.10
, Issue.1
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
41
-
-
0029683606
-
The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
-
Yost C, Torres M, Miller JR, Huang E, Kimelman D, Moon RT. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev. 1996;10(12):1443-1454. (Pubitemid 26260702)
-
(1996)
Genes and Development
, vol.10
, Issue.12
, pp. 1443-1454
-
-
Yost, C.1
Torres, M.2
Miller, J.R.3
Huang, E.4
Kimelman, D.5
Moon, R.T.6
-
42
-
-
0030978351
-
Beta-catenin is a target for the ubiquitin-proteasome pathway
-
Aberle H, Bauer A, Stappert J, Kispert A, Kemler R. Beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 1997; 16(13):3797-3804.
-
(1997)
EMBO J.
, vol.16
, Issue.13
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
43
-
-
0036207075
-
Characterization, expression and complex formation of the murine Fanconi anaemia gene product Fancg
-
DOI 10.1046/j.1365-2443.2002.00518.x
-
van de Vrugt HJ, Koomen M, Berns MA, et al. Characterization, expression and complex formation of the murine Fanconi anaemia gene product Fancg. Genes Cells. 2002;7(3):333-342. (Pubitemid 34257666)
-
(2002)
Genes to Cells
, vol.7
, Issue.3
, pp. 333-342
-
-
Van De, V.H.J.1
Koomen, M.2
Berns, M.A.D.3
De Vries, Y.4
Rooimans, M.A.5
Van Der, W.L.6
Blom, E.7
De Groot, J.8
Schepers, R.J.9
Stone, S.10
Hoatlin, M.E.11
Cheng, N.C.12
Joenje, H.13
Arwert, F.14
-
44
-
-
44649101850
-
Atypical ubiquitin chains: New molecular signals. 'Protein Modifications: Beyond the Usual Suspects' Review Series
-
DOI 10.1038/embor.2008.93, PII EMBOR200893
-
Ikeda F, Dikic I. Atypical ubiquitin chains: new molecular signals. 'Protein modifications: beyond the usual suspects' review series. EMBO Rep. 2008; 9(6):536-542. (Pubitemid 351772916)
-
(2008)
EMBO Reports
, vol.9
, Issue.6
, pp. 536-542
-
-
Ikeda, F.1
Dikic, I.2
-
45
-
-
0032170327
-
beta-TrCP is a negative regulator of the Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos
-
DOI 10.1016/S0925-4773(98)00134-8, PII S0925477398001348
-
Marikawa Y, Elinson RP. beta-TrCP is a negative regulator of Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos. Mech Dev. 1998;77(1):75-80. (Pubitemid 28508986)
-
(1998)
Mechanisms of Development
, vol.77
, Issue.1
, pp. 75-80
-
-
Marikawa, Y.1
Elinson, R.P.2
-
46
-
-
33748749994
-
Lysine residues Lys-19 and Lys-49 of beta-catenin regulate its levels and function in T cell factor transcriptional activation and neoplastic transformation
-
DOI 10.1074/jbc.M604217200
-
Winer IS, Bommer GT, Gonik N, Fearon ER. Lysine residues Lys-19 and Lys-49 of beta-catenin regulate its levels and function in T cell factor transcriptional activation and neoplastic transformation. J Biol Chem. 2006;281(36): 26181-26187. (Pubitemid 44401825)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.36
, pp. 26181-26187
-
-
Winer, I.S.1
Bommer, G.T.2
Gonik, N.3
Fearon, E.R.4
-
47
-
-
53349162212
-
Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL
-
Chitalia VC, Foy RL, Bachschmid MM, et al. Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat Cell Biol. 2008;10(10):1208-1216.
-
(2008)
Nat Cell Biol.
, vol.10
, Issue.10
, pp. 1208-1216
-
-
Chitalia, V.C.1
Foy, R.L.2
Bachschmid, M.M.3
-
48
-
-
0035947080
-
Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses
-
DOI 10.1016/S1097-2765(01)00242-8
-
Matsuzawa SI, Reed JC. Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses. Mol Cell. 2001;7(5):915-926. (Pubitemid 32525739)
-
(2001)
Molecular Cell
, vol.7
, Issue.5
, pp. 915-926
-
-
Matsuzawa, S.-I.1
Reed, J.C.2
-
49
-
-
10744219994
-
Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis
-
DOI 10.1016/S1534-5807(04)00020-6, PII S1534580704000206
-
Nastasi T, Bongiovanni A, Campos Y, et al. Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis. Dev Cell. 2004;6(2):269-282. (Pubitemid 38195218)
-
(2004)
Developmental Cell
, vol.6
, Issue.2
, pp. 269-282
-
-
Nastasi, T.1
Bongiovanni, A.2
Campos, Y.3
Mann, L.4
Toy, J.N.5
Bostrom, J.6
Rottier, R.7
Hahn, C.8
Conaway, J.W.9
Harris, A.J.10
D'Azzo, A.11
-
50
-
-
33744958660
-
The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly
-
DOI 10.1074/jbc.M511411200
-
Gurtan AM, Stuckert P, D'Andrea AD. The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly. J Biol Chem. 2006; 281(16):10896-10905. (Pubitemid 43855513)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.16
, pp. 10896-10905
-
-
Gurtan, A.M.1
Stuckert, P.2
D'Andrea, A.D.3
-
51
-
-
0141484612
-
A novel ubiquitin ligase is deficient in Fanconi anemia
-
DOI 10.1038/ng1241
-
Meetei AR, de Winter JP, Medhurst AL, et al. A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet. 2003;35(2):165-170. (Pubitemid 37187635)
-
(2003)
Nature Genetics
, vol.35
, Issue.2
, pp. 165-170
-
-
Meetei, A.R.1
De Winter, J.P.2
Medhurst, A.L.3
Wallisch, M.4
Waisfisz, Q.5
Van De, V.H.J.6
Oostra, A.B.7
Yan, Z.8
Ling, C.9
Bishop, C.E.10
Hoatlin, M.E.11
Joenje, H.12
Wang, W.13
-
52
-
-
80052747469
-
Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway
-
Hodson C, Cole AR, Lewis LP, Miles JA, Purkiss A, Walden H. Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway. J Biol Chem. 2011;286(37):32628-32637.
-
(2011)
J Biol Chem.
, vol.286
, Issue.37
, pp. 32628-32637
-
-
Hodson, C.1
Cole, A.R.2
Lewis, L.P.3
Miles, J.A.4
Purkiss, A.5
Walden, H.6
-
53
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
DOI 10.1146/annurev.cellbio.20.010403.113126
-
Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol. 2004;20:781-810. (Pubitemid 39488658)
-
(2004)
Annual Review of Cell and Developmental Biology
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
54
-
-
44949231368
-
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling
-
Li W, Bengtson MH, Ulbrich A, et al. Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS One. 2008;3(1):e1487.
-
(2008)
PLoS One.
, vol.3
, Issue.1
-
-
Li, W.1
Bengtson, M.H.2
Ulbrich, A.3
-
55
-
-
0037071398
-
The proto-oncogene c-myc in hematopoietic development and leukemogenesis
-
DOI 10.1038/sj.onc.1205400
-
Hoffman B, Amanullah A, Shafarenko M, Liebermann DA. The proto-oncogene c-myc in hematopoietic development and leukemogenesis. Oncogene. 2002;21(21):3414-3421. (Pubitemid 34587713)
-
(2002)
Oncogene
, vol.21
, Issue.21 REV. ISS. 2
, pp. 3414-3421
-
-
Hoffman, B.1
Amanullah, A.2
Shafarenko, M.3
Liebermann, D.A.4
-
56
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
DOI 10.1038/nature01593
-
Reya T, Duncan AW, Ailles L, et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 2003;423(6938):409-414. (Pubitemid 36626987)
-
(2003)
Nature
, vol.423
, Issue.6938
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
Domen, J.4
Scherer, D.C.5
Willert, K.6
Hintz, L.7
Nusse, R.8
Weissman, I.L.9
-
57
-
-
78649339581
-
Myc transcription factors: Key regulators behind establishment and maintenance of pluripotency
-
Smith K, Dalton S. Myc transcription factors: key regulators behind establishment and maintenance of pluripotency. Regen Med. 2010;5(6): 947-959.
-
(2010)
Regen Med.
, vol.5
, Issue.6
, pp. 947-959
-
-
Smith, K.1
Dalton, S.2
-
58
-
-
58049203043
-
Wnt-related molecules and signaling pathway equilibrium in hematopoiesis
-
Malhotra S, Kincade PW. Wnt-related molecules and signaling pathway equilibrium in hematopoiesis. Cell Stem Cell. 2009;4(1):27-36.
-
(2009)
Cell Stem Cell.
, vol.4
, Issue.1
, pp. 27-36
-
-
Malhotra, S.1
Kincade, P.W.2
-
59
-
-
83455213486
-
Impaired functionality and homing of Fancg-deficient hematopoietic stem cells
-
Barroca V, Mouthon MA, Lewandowski D, et al. Impaired functionality and homing of Fancg-deficient hematopoietic stem cells. Hum Mol Genet. 2012;21(1):121-135.
-
(2012)
Hum Mol Genet
, vol.21
, Issue.1
, pp. 121-135
-
-
Barroca, V.1
Mouthon, M.A.2
Lewandowski, D.3
-
60
-
-
7244250309
-
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
-
DOI 10.1038/nature02989
-
Ito K, Hirao A, Arai F, et al. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature. 2004; 431(7011):997-1002. (Pubitemid 39434422)
-
(2004)
Nature
, vol.431
, Issue.7011
, pp. 997-1002
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Matsuoka, S.4
Takubo, K.5
Hamaguchi, I.6
Nomiyama, K.7
Hosokawa, K.8
Sakurada, K.9
Nakagata, N.10
Ikeda, Y.11
Mak, T.W.12
Suda, T.13
-
61
-
-
33846419112
-
FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress
-
DOI 10.1016/j.cell.2007.01.003, PII S0092867407000505
-
Tothova Z, Kollipara R, Huntly BJ, et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell. 2007;128(2):325-339. (Pubitemid 46137992)
-
(2007)
Cell
, vol.128
, Issue.2
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
Lee, B.H.4
Castrillon, D.H.5
Cullen, D.E.6
McDowell, E.P.7
Lazo-Kallanian, S.8
Williams, I.R.9
Sears, C.10
Armstrong, S.A.11
Passegue, E.12
DePinho, R.A.13
Gilliland, D.G.14
-
62
-
-
20944451595
-
-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy
-
DOI 10.1182/blood-2004-06-2483
-
Li X, Le Beau MM, Ciccone S, et al. Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy. Blood. 2005;105(9):3465-3471. (Pubitemid 40628187)
-
(2005)
Blood
, vol.105
, Issue.9
, pp. 3465-3471
-
-
Li, X.1
Le, B.M.M.2
Ciccone, S.3
Yang, F.-C.4
Freie, B.5
Chen, S.6
Yuan, J.7
Hong, P.8
Orazi, A.9
Haneline, L.S.10
Clapp, D.W.11
-
63
-
-
62949145716
-
Myelodysplasia and acute leukemia as late complications of marrow failure: Future prospects for leukemia prevention
-
Bagby GC, Meyers G. Myelodysplasia and acute leukemia as late complications of marrow failure: future prospects for leukemia prevention. Hematol Oncol Clin North Am. 2009;23(2):361-376.
-
(2009)
Hematol Oncol Clin North Am
, vol.23
, Issue.2
, pp. 361-376
-
-
Bagby, G.C.1
Meyers, G.2
|