Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase

Journal of Cell Biology

Volumn 197, Issue 6, 2012, Pages 761-773

  Rubenstein, Eric M ^a   Kreft, Stefan G ^a,c   Greenblatt, Wesley ^a,d   Swanson, Robert ^b   Hochstrasser, Mark ^a  

^a YALE UNIVERSITY   (United States)

^b VALPARAISO UNIVERSITY   (United States)

^c UNIVERSITY OF KONSTANZ   (Germany)

^d HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; DEG1 PROTEIN; PROTEASOME; SEC62 PROTEIN; TRANSLOCON; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE HRD1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TARGETING;

CYTOPLASM; ENDOPEPTIDASE K; ENDOPLASMIC RETICULUM; MANNOSYL-GLYCOPROTEIN ENDO-BETA-N-ACETYLGLUCOSAMINIDASE; MEMBRANE PROTEINS; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84864022349     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201203061     Document Type: Article

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