ER membrane protein complex required for nuclear fusion

Journal of Cell Biology

Volumn 132, Issue 4, 1996, Pages 499-509

  Ng, Davis T W ^a   Walter, Peter ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN;

ALLELE; ARTICLE; CELL MEMBRANE; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; FLUOROGRAPHY; IMMUNOPRECIPITATION; MEMBRANE FUSION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0030051440     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.132.4.499     Document Type: Article

References (44)

1. Acharya, U., R Jacobs, J.-M. Peters, N. Watson, M.G. Farquar, and V. Malhotra. 1995. The formation of Golgi stacks from vesiculated Golgi membranes requires two distinct fusion events. Cell. 82:895-904
2. Blobel, C.P., T.G. Wolfsberg, C.W. Turck, D.G Myles, P. Primakoff, and J M White. 1992 A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion Nature (Lond.). 356:248-252.
3. Brodsky, J.L., and R. Schekman. 1993. A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome. J. Cell Biol. 123:1355-1363.
4. Chalfie, M., Y. Tu, G. Euskirchen, W.W. Ward, and D.C. Prasher. 1994. Green fluorescent protein as a marker for gene expression. Science (Wash. DC). 263:802-805.
5. Conde, J., and G.R. Fink. 1976. A mutant of Saccharomyces cerevisiae defective for nuclear fusion. Proc Natl Acad. Sci USA. 73:3651-3655.
6. Cyr, D M , T. Langer, and M.G. Douglas. 1994 DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70. Trends Biochem. Sci. 19:176-181.
7. Deshaies, R.J , and R. Schekman. 1987. A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. J. Cell Biol 105.633-645.
8. Deshaies, R.J., and R. Schekman 1989. SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum. J. Cell Biol 109:2653-2664.
9. Deshaies, R.J., S.L. Sanders, D.A. Feldheim, and R. Schekman. 1991. Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex. Nature (Lond.) 349 806-808.
10. Feldheim, D., and R. Schekman. 1994. Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex. J. Cell Biol. 126:935-943.
11. Feldheim, D., J Rothblatt, and R. Schekman. 1992. Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation. Mol. Cell. Biol. 12:3288-3296
12. Feldheim, D., K. Yoshimura, A Admon, and R Schekman 1993. Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum. Mol. Biol. Cell. 4:931-939.
13. Gething, M J., and J Sambrook. 1992. Protein folding in the cell Nature (Lond.) 355:33-45.
14. Green, N., H. Fang, and P. Walter. 1992. Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae. J. Cell Biol. 116:597-604.
15. Deleted in proof.
16. Hann, B.C , and P Walter. 1991 The signal recognition particle in S. cerevisiae Cell. 67:131-144.
17. Huffaker, T.C., J.H. Thomas, and D. Botstein. 1988 Diverse effects of β-tubulin mutations of microtubule formation and function. J Cell Biol. 106:1997-2010.
18. Kurihara, L.J., C.T. Beh, M. Latterich, R. Schekman, and M D. Rose 1994. Nuclear congression and membrane fusion: two distinct events in the yeast karyogamy pathway. J. Cell Biol. 126:911-923
19. Kurihara, T., and P. Silver. 1993. Suppression of a sec63 mutation identifies a novel component of the yeast endoplasmic reticulum translocation apparatus. Mol. Cell Biol. 4:919-930.
20. Latterich, M , and R. Schekman. 1994. The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion. Cell. 78:87-98.
21. Latterich, M., K.-U Fröhlich, and R. Schekman. 1995 Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes. Cell. 82.885-893.
22. Nelson, M.K., T Kurihara, and P.A. Silver. 1993. Extragenic suppressors of mutations in the cytoplasmic C terminus of SEC63 define five genes in Saccharomyces cerevisiae. Genetics 134:159-173.
23. Normington, K., K Kohno, Y. Kozutsumi, M.J. Gething, and J. Sambrook. 1989. S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP. Cell. 57:1223-12236.
24. Nuoffer, C., P. Jeno, A. Conzelmann, and H. Riezman 1991 Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane. Mol. Cell. Biol 11:27-37.
25. Page, B.D., L.L. Satterwhite, M.D. Rose, and M. Snyder. 1994. Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein. J. Cell Biol. 124:507-519.
26. Panzner, S., L. Dreier, E. Hartmann, S. Kostka, and T.A. Rapoport. 1995. Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p Cell. 81:561-570.
27. Polama, J . and J. Conde 1982. Genes involved in the control of nuclear fusion during the sexual cycle of Saccharomyces cerevisiae. Mol. & Gen. Genet. 186.253-258.
28. Prasher, D.C., V.K Eckenrode, W.W. Ward, F G. Prendergast, and M.J. Cormier 1992. Primary structure of the Aequorea victoria green-fluorescent protein. Gene (Amst.). 111:229-233.
29. Preuss, D , J Mulholland, C.A. Kaiser, P. Orlean, C. Albright, M.D Rose, P.W. Robbins, and D. Botstein 1991. Structure of the yeast endoplasmic reticulum, localization of ER proteins using immunofluorescence and immunoelectron microscopy. Yeast 7.891-911.
30. Rabouille, C., T.P. Levine, J.-M. Peters, and G. Warren. 1995. An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. Cell. 82:905-914.
31. Rose, M., and D. Botstein. 1983. Structure and function of the yeast URA3 gene. Differentially regulated expression of hybrid beta-galactosidase from overlapping coding sequences in yeast. J. Mol. Biol. 170:883-904.
32. Rose, M.D. 1991. Nuclear fusion in yeast. Annu. Rev. Microbiol. 45:539-567.
33. Rose, M.D., L.M. Misra, and J.P. Vogel. 1989. KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene. Cell. 57:1211-1221.
34. Rothblatt, J.A., R.J. Deshaies, S.L. Sanders, G. Daum, and R. Schekman. 1989. Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast J. Cell Biol 72:61-68.
35. Sadler, I., A. Chiang, T. Kurihara, J. Rothblatt, J. Way, and P. Silver. 1989. A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein. J Cell Biol. 109:2665-2675.
36. Sambrook, J., E.M. Fritsch, and T Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 545 pp.
37. Scidmore, M.A., H.H. Okamura, and M.D. Rose. 1993. Genetic interactions between KAR2 and SEC63, encoding eukaryotic homologues of DnaK and DnaJ in the endoplasmic reticulum. Mol Biol Cell. 4:1145-1159.
38. Sherman, F., and P. Wakem. 1991. Mapping yeast genes. Methods Enzymol. 194:38-57.
39. Sikorski, R.S., and P. Heiter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics. 122:19-27.
40. Stevens, T.H , J.H. Rothman, G S Payne, and R Schekman. 1986. Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y. J Cell Biol 102:1551-1557.
41. Sullivan, K.M , W.B. Busa, and K.L. Wilson. 1993. Calcium mobilization is required for nuclear vesicle fusion in vitro: implications for membrane traffic and IP3 receptor function. Cell 73:1411-1422.
42. Trueheart, J , J D. Boeke, and G.R. Fink 1987. Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol. Cell. Biol 7:2316-2328.
43. Vogel, J P., L.M. Misra, and M.D. Rose. 1990. Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast. J. Cell Biol. 110:1885-1895.
44. White, J M. 1992. Membrane fusion. Science (Wash. DC). 258:917-924.