-
1
-
-
0002812673
-
Prions (Les Prix Nobel Lecture)
-
In: Frngsmyr T, editors
-
Prusiner SB, (1998) Prions (Les Prix Nobel Lecture). In: Frngsmyr T, editors. pp. 268-323 editor. Les Prix Nobel. Stockholm, Sweden: Almqvist & Wiksell International.
-
(1998)
, pp. 268-323
-
-
Prusiner, S.B.1
-
2
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner SB, (1982) Novel proteinaceous infectious particles cause scrapie. Science 216: 136-144.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
3
-
-
0035859102
-
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
-
Saborio GP, Permanne B, Soto C, (2001) Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411 810-813.
-
(2001)
Nature
, vol.411
, pp. 810-813
-
-
Saborio, G.P.1
Permanne, B.2
Soto, C.3
-
4
-
-
17444413067
-
In vitro generation of infectious scrapie prions
-
Castilla J, Saa P, Hetz C, Soto C, (2005) In vitro generation of infectious scrapie prions. Cell 121 195-206.
-
(2005)
Cell
, vol.121
, pp. 195-206
-
-
Castilla, J.1
Saa, P.2
Hetz, C.3
Soto, C.4
-
5
-
-
67249123069
-
de Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype
-
Barria MA, Mukherjee A, Gonzalez-Romero D, Morales R, Soto C, (2009) de Novo Generation of Infectious Prions In Vitro Produces a New Disease Phenotype. PLOS Pathog 5: e1000421.
-
(2009)
PLOS Pathog
, vol.5
-
-
Barria, M.A.1
Mukherjee, A.2
Gonzalez-Romero, D.3
Morales, R.4
Soto, C.5
-
6
-
-
34547491652
-
Formation of native prions from minimal components in vitro
-
Deleault NR, Harris BT, Rees JR, Supattapone S, (2007) Formation of native prions from minimal components in vitro. ProcAcadNatlSciUSA 104: 9741-9746.
-
(2007)
ProcAcadNatlSciUSA
, vol.104
, pp. 9741-9746
-
-
Deleault, N.R.1
Harris, B.T.2
Rees, J.R.3
Supattapone, S.4
-
7
-
-
77649213673
-
Generating a Prion Bacterially Expressed Recombinant Prion Protein
-
Wang F, Wang X, Yuan CG, Ma J, (2010) Generating a Prion Bacterially Expressed Recombinant Prion Protein. Science 327: 1132-1135.
-
(2010)
Science
, vol.327
, pp. 1132-1135
-
-
Wang, F.1
Wang, X.2
Yuan, C.G.3
Ma, J.4
-
8
-
-
50849116428
-
Accelerated High Fidelity Prion Amplification Within and Across Prion Species Barriers
-
Green KM, Castilla J, Seward TS, Napier DL, Jewell JE, et al. (2008) Accelerated High Fidelity Prion Amplification Within and Across Prion Species Barriers. PLOS Pathog 4: e1000139.
-
(2008)
PLOS Pathog
, vol.4
-
-
Green, K.M.1
Castilla, J.2
Seward, T.S.3
Napier, D.L.4
Jewell, J.E.5
-
9
-
-
50249157526
-
Crossing the Species Barrier by PrPSc Replication In Vitro Generates Unique Infectious Prions
-
Castilla J, Gonzalez-Romero D, Saa P, Morales R, de Castro J, et al. (2008) Crossing the Species Barrier by PrPSc Replication In Vitro Generates Unique Infectious Prions. Cell 134: 757-768.
-
(2008)
Cell
, vol.134
, pp. 757-768
-
-
Castilla, J.1
Gonzalez-Romero, D.2
Saa, P.3
Morales, R.4
de Castro, J.5
-
10
-
-
77951996350
-
Coinfecting prion strains compete for a limiting cellular resource
-
Shikiya RA, Ayers JI, Schutt CR, Kincaid AE, Bartz JC, (2010) Coinfecting prion strains compete for a limiting cellular resource. JVirol 84: 5706-5714.
-
(2010)
JVirol
, vol.84
, pp. 5706-5714
-
-
Shikiya, R.A.1
Ayers, J.I.2
Schutt, C.R.3
Kincaid, A.E.4
Bartz, J.C.5
-
11
-
-
0142184333
-
RNA molecules stimulate prion protein conversion
-
Deleault NR, Lucassen RW, Supattapone S, (2003) RNA molecules stimulate prion protein conversion. Nature 425 717-720.
-
(2003)
Nature
, vol.425
, pp. 717-720
-
-
Deleault, N.R.1
Lucassen, R.W.2
Supattapone, S.3
-
12
-
-
22844438894
-
Protease-resistant Prion Protein Amplification Reconstituted with Partially Purified substrates and Synthetic Polyanions
-
Deleault NR, Geoghegan JC, Nishina K, Kascsak R, Williamson RA, et al. (2005) Protease-resistant Prion Protein Amplification Reconstituted with Partially Purified substrates and Synthetic Polyanions. JBiolChem 280: 26873-26879.
-
(2005)
JBiolChem
, vol.280
, pp. 26873-26879
-
-
Deleault, N.R.1
Geoghegan, J.C.2
Nishina, K.3
Kascsak, R.4
Williamson, R.A.5
-
13
-
-
77951923337
-
Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro
-
Deleault NR, Kascsak R, Geoghegan JC, Supattapone S, (2010) Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro. Biochemistry 49: 3928-3934.
-
(2010)
Biochemistry
, vol.49
, pp. 3928-3934
-
-
Deleault, N.R.1
Kascsak, R.2
Geoghegan, J.C.3
Supattapone, S.4
-
14
-
-
78649726198
-
Plasminogen stimulates propagation of protease-resistant prion protein in vitro Faseb J
-
Mays CE, Ryou C, (2010) Plasminogen stimulates propagation of protease-resistant prion protein in vitro Faseb J 24: 5102-5112.
-
(2010)
, vol.24
, pp. 5102-5112
-
-
Mays, C.E.1
Ryou, C.2
-
15
-
-
33745879463
-
Presymptomatic Detection of Prions in Blood
-
Saa P, Castilla J, Soto C, (2006) Presymptomatic Detection of Prions in Blood. Science 313: 92-94.
-
(2006)
Science
, vol.313
, pp. 92-94
-
-
Saa, P.1
Castilla, J.2
Soto, C.3
-
16
-
-
51249083007
-
Detection of infectious prions in urine
-
Gonzalez-Romero D, Barria MA, Leon P, Morales R, Soto C, (2008) Detection of infectious prions in urine. FEBS Lett 582: 3161-3166.
-
(2008)
FEBS Lett
, vol.582
, pp. 3161-3166
-
-
Gonzalez-Romero, D.1
Barria, M.A.2
Leon, P.3
Morales, R.4
Soto, C.5
-
17
-
-
77951690405
-
Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification
-
Tattum MH, Jones S, Pal S, Collinge J, Jackson GS, (2010) Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification. Transfusion 50: 2619-2627.
-
(2010)
Transfusion
, vol.50
, pp. 2619-2627
-
-
Tattum, M.H.1
Jones, S.2
Pal, S.3
Collinge, J.4
Jackson, G.S.5
-
18
-
-
78049253978
-
Sulfated dextrans enhance in vitro amplification of bovine spongiform encephalopathy PrP(Sc) and enable ultrasensitive detection of bovine PrP(Sc)
-
Murayama Y, Yoshioka M, Masujin K, Okada H, Iwamaru Y, et al. (2010) Sulfated dextrans enhance in vitro amplification of bovine spongiform encephalopathy PrP(Sc) and enable ultrasensitive detection of bovine PrP(Sc). Plos ONE 5: e13152.
-
(2010)
Plos ONE
, vol.5
-
-
Murayama, Y.1
Yoshioka, M.2
Masujin, K.3
Okada, H.4
Iwamaru, Y.5
-
19
-
-
84859193614
-
Fast and ultrasensitive method for quantitating prion infectivity titer
-
Makarava N, Savtchenko R, Alexeeva I, Rohwer RG, Baskakov IV, (2012) Fast and ultrasensitive method for quantitating prion infectivity titer. Nature Commun in press.
-
(2012)
Nature Commun in Press
-
-
Makarava, N.1
Savtchenko, R.2
Alexeeva, I.3
Rohwer, R.G.4
Baskakov, I.V.5
-
20
-
-
37549068149
-
Selective incorporation of polyanionic molecules into hamster prions
-
Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, et al. (2007) Selective incorporation of polyanionic molecules into hamster prions. JBiolChem 282: 36341-36353.
-
(2007)
JBiolChem
, vol.282
, pp. 36341-36353
-
-
Geoghegan, J.C.1
Valdes, P.A.2
Orem, N.R.3
Deleault, N.R.4
Williamson, R.A.5
-
21
-
-
80052702962
-
Relationship between Conformational Stability and Amplification Efficiency of Prions
-
Gonzalez-Montalban N, Makarava N, Savtchenko R, Baskakov IV, (2011) Relationship between Conformational Stability and Amplification Efficiency of Prions. Biochemistry 50: 7933-7940.
-
(2011)
Biochemistry
, vol.50
, pp. 7933-7940
-
-
Gonzalez-Montalban, N.1
Makarava, N.2
Savtchenko, R.3
Baskakov, I.V.4
-
22
-
-
79952213492
-
Highly Efficient Protein Misfolding Cyclic Amplification
-
Gonzalez-Montalban N, Makarava N, Ostapchenko VG, Savtchenko R, Alexeeva I, et al. (2011) Highly Efficient Protein Misfolding Cyclic Amplification. PLoS Pathogen 7: e1001277.
-
(2011)
PLoS Pathogen
, vol.7
-
-
Gonzalez-Montalban, N.1
Makarava, N.2
Ostapchenko, V.G.3
Savtchenko, R.4
Alexeeva, I.5
-
23
-
-
79957590414
-
Quantitative detection and biological propagation of scrapie seeding activity in vitro facilitate use of prions as model pathogens for disinfection
-
Pritzkow S, Wagenfuhr K, Daus ML, Boerner S, Lemmer K, et al. (2011) Quantitative detection and biological propagation of scrapie seeding activity in vitro facilitate use of prions as model pathogens for disinfection. Plos ONE 6: e20384.
-
(2011)
Plos ONE
, vol.6
-
-
Pritzkow, S.1
Wagenfuhr, K.2
Daus, M.L.3
Boerner, S.4
Lemmer, K.5
-
24
-
-
0035086136
-
Strain-specified relative conformational stability of the scrapie prion protein
-
Peretz D, Scott M, Groth D, Williamson A, Burton D, et al. (2001) Strain-specified relative conformational stability of the scrapie prion protein. Protein Sci 10: 854-863.
-
(2001)
Protein Sci
, vol.10
, pp. 854-863
-
-
Peretz, D.1
Scott, M.2
Groth, D.3
Williamson, A.4
Burton, D.5
-
25
-
-
79953286302
-
The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease
-
Ayers JL, Schutt CR, Shikiya RA, Aguzzi A, Kincaid AE, et al. (2011) The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease. PLOS Pathog 7: e1001317.
-
(2011)
PLOS Pathog
, vol.7
-
-
Ayers, J.L.1
Schutt, C.R.2
Shikiya, R.A.3
Aguzzi, A.4
Kincaid, A.E.5
-
26
-
-
24644448839
-
The most infectious prion protein particles
-
Silveira JR, Raymond GJ, Hughson A, Race RE, Sim VL, et al. (2005) The most infectious prion protein particles. Nature 437 257-261.
-
(2005)
Nature
, vol.437
, pp. 257-261
-
-
Silveira, J.R.1
Raymond, G.J.2
Hughson, A.3
Race, R.E.4
Sim, V.L.5
-
27
-
-
77954051480
-
The physical relationship between infectivity and prion protein aggregates is strain-dependent
-
Tixador P, Herzog L, Reine F, Jaumain E, Chapuis J, et al. (2010) The physical relationship between infectivity and prion protein aggregates is strain-dependent. PLOS Pathog 6: e1000859.
-
(2010)
PLOS Pathog
, vol.6
-
-
Tixador, P.1
Herzog, L.2
Reine, F.3
Jaumain, E.4
Chapuis, J.5
-
28
-
-
84860903170
-
Biochemical properties of highly neuroinvasive prion strains
-
Bett C, Joshi-Barr S, Lucero M, Trejo M, Liberski P, et al. (2012) Biochemical properties of highly neuroinvasive prion strains. PLOS Pathog 8: e1002522.
-
(2012)
PLOS Pathog
, vol.8
-
-
Bett, C.1
Joshi-Barr, S.2
Lucero, M.3
Trejo, M.4
Liberski, P.5
-
29
-
-
77449142074
-
Recombinant prion protein induces a new transmissible prion disease in wild type animals
-
Makarava N, Kovacs GG, Bocharova OV, Savtchenko R, Alexeeva I, et al. (2010) Recombinant prion protein induces a new transmissible prion disease in wild type animals. Acta Neuropathol 119: 177-187.
-
(2010)
Acta Neuropathol
, vol.119
, pp. 177-187
-
-
Makarava, N.1
Kovacs, G.G.2
Bocharova, O.V.3
Savtchenko, R.4
Alexeeva, I.5
-
30
-
-
84855290517
-
Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease
-
Makarava N, Kovacs GG, Savtchenko R, Alexeeva I, Budka H, et al. (2011) Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease. PLoS Pathogen 7: e1002419.
-
(2011)
PLoS Pathogen
, vol.7
-
-
Makarava, N.1
Kovacs, G.G.2
Savtchenko, R.3
Alexeeva, I.4
Budka, H.5
-
31
-
-
81755187224
-
Ultra-efficient PrP(Sc) amplification highlights potentialities and pitfalls of PMCA technology
-
Cosseddu GM, Nonno R, Vaccari G, Bucalossi C, Fernandez-Borges N, et al. (2011) Ultra-efficient PrP(Sc) amplification highlights potentialities and pitfalls of PMCA technology. PLOS Pathog 7: e1002370.
-
(2011)
PLOS Pathog
, vol.7
-
-
Cosseddu, G.M.1
Nonno, R.2
Vaccari, G.3
Bucalossi, C.4
Fernandez-Borges, N.5
-
32
-
-
33751572491
-
The Stoichiometry of Host PrPC Glycoforms Modulates the Efficiency of PrPSc formation in vitro
-
Nishina K, Deleault NR, Mahal S, Baskakov I, Luhrs T, et al. (2006) The Stoichiometry of Host PrPC Glycoforms Modulates the Efficiency of PrPSc formation in vitro. Biochemistry 45: 14129-14139.
-
(2006)
Biochemistry
, vol.45
, pp. 14129-14139
-
-
Nishina, K.1
Deleault, N.R.2
Mahal, S.3
Baskakov, I.4
Luhrs, T.5
-
33
-
-
76749109480
-
Darwinian evolution of prions in cell culture
-
Li J, Browning S, Mahal SP, Oelschlegel AM, Weissmann C, (2010) Darwinian evolution of prions in cell culture. Science 327: 869-872.
-
(2010)
Science
, vol.327
, pp. 869-872
-
-
Li, J.1
Browning, S.2
Mahal, S.P.3
Oelschlegel, A.M.4
Weissmann, C.5
-
34
-
-
36049020231
-
A General Model of Prion Strains and Their Pathogenicity
-
Collinge J, Clarke AR, (2007) A General Model of Prion Strains and Their Pathogenicity. Science 318: 930-936.
-
(2007)
Science
, vol.318
, pp. 930-936
-
-
Collinge, J.1
Clarke, A.R.2
-
36
-
-
84855857565
-
In vitro generation of high titer prions
-
Shikiya AS, Bartz JC, (2011) In vitro generation of high titer prions. JVirol 85: 13439-13442.
-
(2011)
JVirol
, vol.85
, pp. 13439-13442
-
-
Shikiya, A.S.1
Bartz, J.C.2
-
37
-
-
39049119728
-
Conformational stability of PrP amyloid firbils controls their smallest possible fragment size
-
Sun Y, Makarava N, Lee CI, Laksanalamai P, Robb FT, et al. (2008) Conformational stability of PrP amyloid firbils controls their smallest possible fragment size. JMolBiol 376: 1155-1167.
-
(2008)
JMolBiol
, vol.376
, pp. 1155-1167
-
-
Sun, Y.1
Makarava, N.2
Lee, C.I.3
Laksanalamai, P.4
Robb, F.T.5
-
38
-
-
13844321726
-
Strain-specified characteristics of mouse synthetic prions
-
Legname G, Nguyen HOB, Baskakov IV, Cohen FE, DeArmond SJ, et al. (2005) Strain-specified characteristics of mouse synthetic prions. ProcNatlAcaSciUSA 102: 2168-2173.
-
(2005)
ProcNatlAcaSciUSA
, vol.102
, pp. 2168-2173
-
-
Legname, G.1
Nguyen, H.O.B.2
Baskakov, I.V.3
Cohen, F.E.4
DeArmond, S.J.5
-
39
-
-
73949160065
-
Design and construction of diverse mammalian prion strains
-
Colby DW, Giles K, Legname G, Wille H, Baskakov IV, et al. (2009) Design and construction of diverse mammalian prion strains. ProcAcadNatlSciUSA 106: 20417-20422.
-
(2009)
ProcAcadNatlSciUSA
, vol.106
, pp. 20417-20422
-
-
Colby, D.W.1
Giles, K.2
Legname, G.3
Wille, H.4
Baskakov, I.V.5
|