Quantitative detection and biological propagation of scrapie seeding activity in vitro facilitate use of prions as model pathogens for disinfection

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Pritzkow, Sandra ^a   Wagenführ, Katja ^a   Daus, Martin L ^a   Boerner, Susann ^a   Lemmer, Karin ^a   Thomzig, Achim ^a   Mielke, Martin ^a   Beekes, Michael ^a  

^a ROBERT KOCH INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DISINFECTANT AGENT; DODECYL SULFATE SODIUM; GLUTARALDEHYDE; GUANIDINE THIOCYANATE; HYPOCHLORITE SODIUM; PERACETIC ACID; PHTHALALDEHYDE; PRION PROTEIN; PROPANOL; PROTEINASE; SODIUM HYDROXIDE; STAINLESS STEEL; UNCLASSIFIED DRUG; STEEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CALIBRATION; CONTROLLED STUDY; DISINFECTION; GENE AMPLIFICATION; GLIA CELL; HAMSTER; IN VITRO STUDY; INSTRUMENT STERILIZATION; METHODOLOGY; NONHUMAN; PROTEIN MISFOLDING CYCLIC AMPLIFICATION; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SCRAPIE; SENSITIVITY AND SPECIFICITY; VIRAL CONTAMINATION; VIRUS INFECTIVITY; VIRUS LOAD; VIRUS TITRATION; WATER VAPOR; ANIMAL; BIOASSAY; CHEMISTRY; DISEASE TRANSMISSION; GLIA; METABOLISM; PATHOLOGY; PRION; PROTEIN FOLDING;

ANIMALIA; CRICETINAE; FUNGI;

ANIMALS; BIOLOGICAL ASSAY; CRICETINAE; DISINFECTION; NEUROGLIA; PRIONS; PROTEIN FOLDING; REPRODUCIBILITY OF RESULTS; SCRAPIE; STEEL;

EID: 79957590414     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020384     Document Type: Article

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