메뉴 건너뛰기




Volumn 36, Issue 9, 2012, Pages 1128-1133

Decreased DNA methylation in acute myeloid leukemia patients with DNMT3A mutations and prognostic implications of DNA methylation

Author keywords

AML; DNA methylation; DNMT3A mutations; Prognosis

Indexed keywords

DNA METHYLTRANSFERASE 3A; GENOMIC DNA; HOMEODOMAIN PROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 84864007553     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2012.05.012     Document Type: Article
Times cited : (43)

References (31)
  • 1
    • 0034176798 scopus 로고    scopus 로고
    • DNA hypermethylation in tumorigenesis: epigenetics joins genetics
    • Baylin S.B., Herman J.G. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000, 16(4):168-174.
    • (2000) Trends Genet , vol.16 , Issue.4 , pp. 168-174
    • Baylin, S.B.1    Herman, J.G.2
  • 2
    • 60849089645 scopus 로고    scopus 로고
    • Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
    • Jiang Y., Dunbar A., Gondek L.P., Mohan S., Rataul M., O'Keefe C., et al. Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. Blood 2009, 113(6):1315-1325.
    • (2009) Blood , vol.113 , Issue.6 , pp. 1315-1325
    • Jiang, Y.1    Dunbar, A.2    Gondek, L.P.3    Mohan, S.4    Rataul, M.5    O'Keefe, C.6
  • 3
    • 72949114887 scopus 로고    scopus 로고
    • Leukaemogenesis: more than mutant genes
    • Chen J., Odenike O., Rowley J.D. Leukaemogenesis: more than mutant genes. Nat Rev Cancer 2010, 10(1):23-36.
    • (2010) Nat Rev Cancer , vol.10 , Issue.1 , pp. 23-36
    • Chen, J.1    Odenike, O.2    Rowley, J.D.3
  • 4
    • 77955081371 scopus 로고    scopus 로고
    • Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1 TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias
    • Rocquain J., Carbuccia N., Trouplin V., Raynaud S., Murati A., Nezri M., et al. Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1 TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias. BMC Cancer 2010, 10:401.
    • (2010) BMC Cancer , vol.10 , pp. 401
    • Rocquain, J.1    Carbuccia, N.2    Trouplin, V.3    Raynaud, S.4    Murati, A.5    Nezri, M.6
  • 5
    • 80051931772 scopus 로고    scopus 로고
    • New mutations and pathogenesis of myeloproliferative neoplasms
    • Vainchenker W., Delhommeau F., Constantinescu S.N., Bernard O.A. New mutations and pathogenesis of myeloproliferative neoplasms. Blood 2011, 118(7):1723-1735.
    • (2011) Blood , vol.118 , Issue.7 , pp. 1723-1735
    • Vainchenker, W.1    Delhommeau, F.2    Constantinescu, S.N.3    Bernard, O.A.4
  • 7
    • 79960735923 scopus 로고    scopus 로고
    • Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia
    • Thol F., Damm F., Ludeking A., Winschel C., Wagner K., Morgan M., et al. Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia. J Clin Oncol 2011, 29(21):2889-2896.
    • (2011) J Clin Oncol , vol.29 , Issue.21 , pp. 2889-2896
    • Thol, F.1    Damm, F.2    Ludeking, A.3    Winschel, C.4    Wagner, K.5    Morgan, M.6
  • 8
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor T.H. The DNA methyltransferases of mammals. Hum Mol Genet 2000, 9(16):2395-2402.
    • (2000) Hum Mol Genet , vol.9 , Issue.16 , pp. 2395-2402
    • Bestor, T.H.1
  • 9
    • 67349255210 scopus 로고    scopus 로고
    • CpG islands - 'a rough guide'
    • Illingworth R.S., Bird A.P. CpG islands - 'a rough guide'. FEBS Lett 2009, 583(11):1713-1720.
    • (2009) FEBS Lett , vol.583 , Issue.11 , pp. 1713-1720
    • Illingworth, R.S.1    Bird, A.P.2
  • 10
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E., Bestor T.H., Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69(6):915-926.
    • (1992) Cell , vol.69 , Issue.6 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 11
    • 0033547330 scopus 로고    scopus 로고
    • Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
    • Xu G.L., Bestor T.H., Bourc'his D., Hsieh C.L., Tommerup N., Bugge M., et al. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 1999, 402(6758):187-191.
    • (1999) Nature , vol.402 , Issue.6758 , pp. 187-191
    • Xu, G.L.1    Bestor, T.H.2    Bourc'his, D.3    Hsieh, C.L.4    Tommerup, N.5    Bugge, M.6
  • 13
    • 0033179375 scopus 로고    scopus 로고
    • Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
    • Melki J.R., Vincent P.C., Clark S.J. Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res 1999, 59(15):3730-3740.
    • (1999) Cancer Res , vol.59 , Issue.15 , pp. 3730-3740
    • Melki, J.R.1    Vincent, P.C.2    Clark, S.J.3
  • 15
    • 0035798454 scopus 로고    scopus 로고
    • Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas
    • Arnold J.M., Cummings M., Purdie D., Chenevix-Trench G. Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas. Br J Cancer 2001, 85(9):1351-1358.
    • (2001) Br J Cancer , vol.85 , Issue.9 , pp. 1351-1358
    • Arnold, J.M.1    Cummings, M.2    Purdie, D.3    Chenevix-Trench, G.4
  • 16
    • 78449247471 scopus 로고    scopus 로고
    • Epigenetic differences in cytogenetically normal versus abnormal acute myeloid leukemia
    • Griffiths E.A., Gore S.D., Hooker C.M., Mohammad H.P., McDevitt M.A., Smith B.D., et al. Epigenetic differences in cytogenetically normal versus abnormal acute myeloid leukemia. Epigenetics 2010, 5(7):590-600.
    • (2010) Epigenetics , vol.5 , Issue.7 , pp. 590-600
    • Griffiths, E.A.1    Gore, S.D.2    Hooker, C.M.3    Mohammad, H.P.4    McDevitt, M.A.5    Smith, B.D.6
  • 17
    • 79953176952 scopus 로고    scopus 로고
    • Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
    • Yan X.J., Xu J., Gu Z.H., Pan C.M., Lu G., Shen Y., et al. Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet 2011, 43(4):309-315.
    • (2011) Nat Genet , vol.43 , Issue.4 , pp. 309-315
    • Yan, X.J.1    Xu, J.2    Gu, Z.H.3    Pan, C.M.4    Lu, G.5    Shen, Y.6
  • 18
    • 80655125052 scopus 로고    scopus 로고
    • Cytogenetic abnormalities in adult non-promyelocytic acute myeloid leukemia: a concise review
    • Marchesi F., Annibali O., Cerchiara E., Tirindelli M.C., Avvisati G. Cytogenetic abnormalities in adult non-promyelocytic acute myeloid leukemia: a concise review. Crit Rev Oncol Hematol 2011, 80(3):331-346.
    • (2011) Crit Rev Oncol Hematol , vol.80 , Issue.3 , pp. 331-346
    • Marchesi, F.1    Annibali, O.2    Cerchiara, E.3    Tirindelli, M.C.4    Avvisati, G.5
  • 19
    • 78149263150 scopus 로고    scopus 로고
    • Monitoring of minimal residual disease in patients with core binding factor acute myeloid leukemia and the impact of C-KIT FLT3, and JAK2 mutations on clinical outcome
    • Marková J., Trnková Z., Michková P., Maaloufová J., Starý J., Cetkovský P., et al. Monitoring of minimal residual disease in patients with core binding factor acute myeloid leukemia and the impact of C-KIT FLT3, and JAK2 mutations on clinical outcome. Leuk Lymphoma 2009, 50:1448-1460.
    • (2009) Leuk Lymphoma , vol.50 , pp. 1448-1460
    • Marková, J.1    Trnková, Z.2    Michková, P.3    Maaloufová, J.4    Starý, J.5    Cetkovský, P.6
  • 22
    • 27744585182 scopus 로고    scopus 로고
    • Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma
    • Friedrich M.G., Chandrasoma S., Siegmund K.D., Weisenberger D.J., Cheng J.C., Toma M.I., et al. Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma. Eur J Cancer 2005, 41(17):2769-2778.
    • (2005) Eur J Cancer , vol.41 , Issue.17 , pp. 2769-2778
    • Friedrich, M.G.1    Chandrasoma, S.2    Siegmund, K.D.3    Weisenberger, D.J.4    Cheng, J.C.5    Toma, M.I.6
  • 23
    • 33744550591 scopus 로고    scopus 로고
    • Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis
    • Ogino S., Kawasaki T., Brahmandam M., Cantor M., Kirkner G.J., Spiegelman D., et al. Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn 2006, 8(2):209-217.
    • (2006) J Mol Diagn , vol.8 , Issue.2 , pp. 209-217
    • Ogino, S.1    Kawasaki, T.2    Brahmandam, M.3    Cantor, M.4    Kirkner, G.J.5    Spiegelman, D.6
  • 25
    • 84855853131 scopus 로고    scopus 로고
    • Prognostic impact of DNMT3A mutations in patients with intermediate cytogenetic risk profile acute myeloid leukemia
    • Marková J., Michková P., Burčková K., Březinová J., Michalová K., Dohnalová A., et al. Prognostic impact of DNMT3A mutations in patients with intermediate cytogenetic risk profile acute myeloid leukemia. Eur J Haematol 2012, 88:128-135.
    • (2012) Eur J Haematol , vol.88 , pp. 128-135
    • Marková, J.1    Michková, P.2    Burčková, K.3    Březinová, J.4    Michalová, K.5    Dohnalová, A.6
  • 26
    • 77952331728 scopus 로고    scopus 로고
    • Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia
    • Deneberg S., Grövdal M., Karimi M., Jansson M., Nahi H., Corbacioglu A., et al. Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia. Leukemia 2010, 24(5):932-941.
    • (2010) Leukemia , vol.24 , Issue.5 , pp. 932-941
    • Deneberg, S.1    Grövdal, M.2    Karimi, M.3    Jansson, M.4    Nahi, H.5    Corbacioglu, A.6
  • 27
    • 84864015790 scopus 로고    scopus 로고
    • Increased DNA methylation is associated with good prognosis in AML
    • Kroeger H., Jelinek J., Komblau S.M., Bueso-Ramos C.E., Issa J.P. Increased DNA methylation is associated with good prognosis in AML. Blood 2007, 110(11):183A.
    • (2007) Blood , vol.110 , Issue.11
    • Kroeger, H.1    Jelinek, J.2    Komblau, S.M.3    Bueso-Ramos, C.E.4    Issa, J.P.5
  • 28
    • 78651331694 scopus 로고    scopus 로고
    • CEBPA methylation as a prognostic biomarker in patients with de novo acute myeloid leukemia
    • Lin T.C., Hou H.A., Chou W.C., Ou D.L., Yu S.L., Tien H.F., et al. CEBPA methylation as a prognostic biomarker in patients with de novo acute myeloid leukemia. Leukemia 2011, 25(1):32-40.
    • (2011) Leukemia , vol.25 , Issue.1 , pp. 32-40
    • Lin, T.C.1    Hou, H.A.2    Chou, W.C.3    Ou, D.L.4    Yu, S.L.5    Tien, H.F.6
  • 29
    • 18044374452 scopus 로고    scopus 로고
    • Methylation of p15(INK4b) and E-cadherin genes is independently correlated with poor prognosis in acute myeloid leukemia
    • Shimamoto T., Ohyashiki J.H., Ohyashiki K. Methylation of p15(INK4b) and E-cadherin genes is independently correlated with poor prognosis in acute myeloid leukemia. Leuk Res 2005, 29(6):653-659.
    • (2005) Leuk Res , vol.29 , Issue.6 , pp. 653-659
    • Shimamoto, T.1    Ohyashiki, J.H.2    Ohyashiki, K.3
  • 30
    • 0141502199 scopus 로고    scopus 로고
    • Methylation of p15(INK4B) is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia
    • Christiansen D.H., Andersen M.K., Pedersen-Bjergaard J. Methylation of p15(INK4B) is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 2003, 17(9):1813-1819.
    • (2003) Leukemia , vol.17 , Issue.9 , pp. 1813-1819
    • Christiansen, D.H.1    Andersen, M.K.2    Pedersen-Bjergaard, J.3
  • 31
    • 77957928566 scopus 로고    scopus 로고
    • DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia
    • Alvarez S., Suela J., Valencia A., Fernández A., Wunderlich M., Agirre X., et al. DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia. Plos One 2010, 5(8):e12197.
    • (2010) Plos One , vol.5 , Issue.8
    • Alvarez, S.1    Suela, J.2    Valencia, A.3    Fernández, A.4    Wunderlich, M.5    Agirre, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.