Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma

European Journal of Cancer

Volumn 41, Issue 17, 2005, Pages 2769-2778

  Friedrich, Martin G ^a,b   Chandrasoma, Shahin ^a   Siegmund, Kimberly D ^a   Weisenberger, Daniel J ^a   Cheng, Jonathan C ^a   Toma, Marieta I ^b   Huland, Hartwig ^b   Jones, Peter A ^a   Liang, Gangning ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Bladder; Cancer associated genes; Methylation markers; Non invasive

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; DEATH ASSOCIATED PROTEIN KINASE; DEATH RECEPTOR; DEATH RECEPTOR 3; ENDOTHELIN B RECEPTOR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MLH1; PROTEIN P14ARF; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TELOMERASE REVERSE TRANSCRIPTASE; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG; UVOMORULIN;

ADULT; AGED; ARTICLE; BLADDER CARCINOMA; CANCER CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CPG ISLAND; DISEASE ASSOCIATION; DNA METHYLATION; EPIGENETICS; FEMALE; FOLLOW UP; GENE IDENTIFICATION; GENE MUTATION; HUMAN; HUMAN TISSUE; INVASIVE CARCINOMA; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MARKER GENE; MICRODISSECTION; MUSCLE CANCER; NUCLEOTIDE SEQUENCE; OBSERVATION; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; QUANTITATIVE ANALYSIS; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; RECURRENT CANCER; SAMPLE SIZE; SENSITIVITY ANALYSIS; TRANSURETHRAL RESECTION; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; COHORT STUDIES; DISEASE-FREE SURVIVAL; DNA METHYLATION; FEMALE; GENES, NEOPLASM; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; POLYMERASE CHAIN REACTION; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; URINARY BLADDER NEOPLASMS;

EID: 27744585182     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2005.07.019     Document Type: Article

References (37)

1. S. Holmang, H. Hedelin, and C. Anderstrom Recurrence and progression in low grade papillary urothelial tumours J Urol 162 3 Pt 1 1999 702 707
2. D.K. Chopin, and B. Gattegno Superficial bladder tumours Eur Urol 42 6 2002 533 541
3. P.W. Laird The power and the promise of DNA methylation markers Nat Rev Cancer 3 4 2003 253 266
4. P.A. Jones, and S.B. Baylin The fundamental role of epigenetic events in cancer Nat Rev Genet 3 6 2002 415 428
5. P.A. Jones, and P.W. Laird Cancer epigenetics comes of age Nat Genet 21 2 1999 163 167
6. M.G. Friedrich, D.J. Weisenberger, and J.C. Cheng Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients Clin Cancer Res 10 22 2004 7457 7465
7. M.M. Pao, M. Tsutsumi, and G. Liang The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumour cells Hum Mol Genet 10 9 2001 903 910
8. M.W. Chan, L.W. Chan, and N.L. Tang Hypermethylation of multiple genes in tumour tissues and voided urine in urinary bladder cancer patients Clin Cancer Res 8 2 2002 464 470
9. Y. Tada, M. Wada, and K. Taguchi The association of death-associated protein kinase hypermethylation with early recurrence in superficial bladder cancers Cancer Res 62 14 2002 4048 4053
10. L.A. Ribeiro-Filho, J. Franks, and M. Sasaki CpG hypermethylation of promoter region and inactivation of E-cadherin gene in human bladder cancer Mol Carcinog 34 4 2002 187 198
11. Y. Horikawa, K. Sugano, and M. Shigyo Hypermethylation of an E-cadherin (CDH1) promoter region in high grade transitional cell carcinoma of the bladder comprising carcinoma in situ J Urol 169 4 2003 1541 1545
12. D.M. Bornman, S. Mathew, and J. Alsruhe Methylation of the E-cadherin gene in bladder neoplasia and in normal urothelial epithelium from elderly individuals Am J Pathol 159 3 2001 831 835
13. G. Liang, K.D. Robertson, and C. Talmadge The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumour cells Cancer Res 60 17 2000 4907 4912
14. M. Esteller, P.G. Corn, and S.B. Baylin A gene hypermethylation profile of human cancer Cancer Res 61 8 2001 3225 3229
15. O. Galm, H. Yoshikawa, and M. Esteller SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma Blood 101 7 2003 2784 2788
16. W.J. Babidge, L.M. Butler, and M.A. Burton Methylation of CpG sites in exon 2 of the bcl-2 gene occurs in colorectal carcinoma Anticancer Res 21 4A 2001 2809 2814
17. T.R. Devereux, I. Horikawa, and C.H. Anna DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene Cancer Res 59 24 1999 6087 6090
18. M.D. Vos, C.A. Ellis, and A. Bell Ras uses the novel tumour suppressor RASSF1 as an effector to mediate apoptosis J Biol Chem 275 46 2000 35669 35672
19. K.E. Conway, B.B. McConnell, and C.E. Bowring TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers Cancer Res 60 22 2000 6236 6242
20. J.M. Arnold, M. Cummings, and D. Purdie Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas Br J Cancer 85 9 2001 1351 1358
21. K.E. Bachman, J.G. Herman, and P.G. Corn Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers Cancer Res 59 4 1999 798 802
22. A.R. Karpf, P.W. Peterson, and J.T. Rawlins Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumour cells Proc Natl Acad Sci USA 96 24 1999 14007 14012
23. C.A. Eads, K.D. Danenberg, and K. Kawakami MethyLight: a high-throughput assay to measure DNA methylation Nucleic Acids Res 28 8 2000 E32
24. J.L. Masferrer, K.M. Leahy, and A.T. Koki Antiangiogenic and antitumour activities of cyclooxygenase-2 inhibitors Cancer Res 60 5 2000 1306 1311
25. A.J. Marrogi, W.D. Travis, and J.A. Welsh Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma Clin Cancer Res 6 12 2000 4739 4744
26. Y. Miyata, S. Koga, and S. Kanda Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumour cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival Clin Cancer Res 9 5 2003 1741 1749
27. G. Narayan, H. Arias-Pulido, and S. Koul Frequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: its relationship to clinical outcome Mol Cancer 2 1 2003 24
28. R. Schneider-Stock, C. Boltze, and J. Lasota High prognostic value of p16INK4 alterations in gastrointestinal stromal tumours J Clin Oncol 21 9 2003 1688 1697
29. J. Roman-Gomez, J.A. Castillejo, and A. Jimenez 5′ CpG island hypermethylation is associated with transcriptional silencing of the p21 (CIP1/WAF1/SDI1) gene and confers poor prognosis in acute lymphoblastic leukemia Blood 99 7 2002 2291 2296
30. R. Maruyama, S. Toyooka, and K.O. Toyooka Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features Cancer Res 61 24 2001 8659 8663
31. E.M. Bindels, M. Vermey, and R. van den Beemd E-cadherin promotes intraepithelial expansion of bladder carcinoma cells in an in vitro model of carcinoma in situ Cancer Res 60 1 2000 177 183
32. S.F. Shariat, S. Pahlavan, and A.G. Baseman E-cadherin expression predicts clinical outcome in carcinoma in situ of the urinary bladder Urology 57 1 2001 60 65
33. R.R. Byrne, S.F. Shariat, and R. Brown E-cadherin immunostaining of bladder transitional cell carcinoma, carcinoma in situ and lymph node metastases with long-term followup J Urol 165 5 2001 1473 1479
34. X. Garcia del Muro, A. Torregrosa, and J. Munoz Prognostic value of the expression of E-cadherin and beta-catenin in bladder cancer Eur J Cancer 36 3 2000 357 362
35. E. Solsona, I. Iborra, and J.V. Ricos Effectiveness of a single immediate mitomycin C instillation in patients with low-risk superficial bladder cancer: short and long-term followup J Urol 161 4 1999 1120 1123
36. A. Wild, A. Ramaswamy, and P. Langer Frequent methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene in pancreatic endocrine tumours J Clin Endocrinol Metab 88 3 2003 1367 1373
37. S. Zochbauer-Muller, K.M. Fong, and A.K. Virmani Aberrant promoter methylation of multiple genes in non-small cell lung cancers Cancer Res 61 1 2001 249 255