CD40 amplifies Fas-mediated apoptosis: A mechanism contributing to emphysema

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 303, Issue 2, 2012, Pages

  Shigeta, Ayako ^a   Tada, Yuji ^a   Wang, Ji Yang ^b   Ishizaki, Shunsuke ^a   Tsuyusaki, Junichi ^a   Yamauchi, Keita ^a   Kasahara, Yasunori ^a   Iesato, Ken ^a   Tanabe, Nobuhiro ^a   Takiguchi, Yuichi ^a   Sakamoto, Akemi ^c   Tokuhisa, Takeshi ^c   Shibuya, Kazutoshi ^d,e   Hiroshima, Kenzo ^f   West, James ^g   Tatsumi, Koichiro ^a  

^a CHIBA UNIVERSITY   (Japan)

^b RIKEN YOKOHAMA INSTITUTE   (Japan)

^c CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e PEKING UNIVERSITY FIRST HOSPITAL   (China)

^f Tokyo Women s Medical University   (Japan)

^g VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Alveolus; Chemokine regulated on activation normal T cells expressed and secreted (RANTES); IFN ; Inflammation

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; FAS ANTIGEN; GAMMA INTERFERON;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; EMPHYSEMA; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG LAVAGE; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SMOKING;

AGED; ANIMALS; ANTIBODIES; ANTIGENS, CD40; ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CD40 LIGAND; CELLS, CULTURED; CHEMOKINES, CC; ENDOTHELIAL CELLS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; INTERFERON-GAMMA; LUNG; MALE; MICE; MICE, INBRED C57BL; MICROVESSELS; PULMONARY ALVEOLI; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; RECEPTORS, CCR5;

EID: 84863906812     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00337.2011     Document Type: Article

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