CD40 Ligand Stimulates Proinflammatory Cytokine Production by Human Endothelial Cells

Journal of Immunology

Volumn 159, Issue 11, 1997, Pages 5640-5647

  Déchanet, Julie ^a,c   Grosset, Christophe ^a   Taupin, Jean Luc ^a   Merville, Pierre ^b   Banchereau, Jacques ^d   Ripoche, Jean ^a   Moreau, Jean François ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b HÔPITAL PELLEGRIN   (France)

^c CNRS Bordeaux Segalen University   (France)

^d BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; CYCLOSPORIN; CYTOKINE; DEXAMETHASONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH INHIBITOR; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; LIF PROTEIN, HUMAN; LIGAND; LYMPHOKINE; MEMBRANE PROTEIN;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DIVISION; HUMAN; METABOLISM; VASCULAR ENDOTHELIUM;

ANTIGENS, CD40; APOPTOSIS; CD40 LIGAND; CELL DIVISION; CELLS, CULTURED; CYCLOSPORINE; CYTOKINES; DEXAMETHASONE; ENDOTHELIUM, VASCULAR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; GROWTH INHIBITORS; HUMANS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LIGANDS; LYMPHOKINES; MEMBRANE GLYCOPROTEINS;

EID: 0031297249     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Banchereau, J., F. Bazan, D. Blanchard, F. Brière, J. P. Galizzi, K. van Kooten, Y. J. Liu, F. Rousset, and S. Saeland. 1994. The CD40 antigen and its ligand. Annu. Rev. Immunol. 12:881.
2. Schriever, F., A. S. Freedman, G. Freeman, E. Messner, G. Lee, J. Daley, and L. M. Nadler. 1989. Isolated human follicular dendritic cells display a unique antigenic phenotype. J. Exp. Med. 169:2043.
3. Alderson, M. R., R. J. Armitage, T. W. Tough, L. Strockbine, W. C. Fanslow, and M. K. Spriggs. 1993. CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand of CD40. J. Exp. Med. 178: 669.
4. + hematopoietic cells. Exp. Hematol. 20:24.
5. Galy, A. H., and H. Spits. 1992. CD40 is functionally expressed on human thymic epithelial cells. J. Immunol. 149:775.
6. Yellin, M. J., S. Winikoff, S. M. Fortune, D. Baum, M. K. Crow, S. Lederman, and L. Chess. 1995. Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) upregulation, IL-6 production and proliferation. J. Leukocyte Biol. 58:209.
7. Paulie, S., B. Ehlin-Hendricksson, H. Mellstedt, H. Koho, H. Ben-Aissa, and P. Perlman. 1985. Ap50 surface antigen restricted to human urinary bladder carcinomas and B lymphocytes. Cancer Immunol. Immunother. 20:23.
8. Armitage, R. J., W. C. Fanslow, L. Strockbine, T. A. Sato, K. N. Clifford, B. M. Macduff, D. M. Anderson, S. D. Gimpel, T. Daveis-Smith, C. R. Maliszewski, E. A. Clark, C. A. Smith, K. H. Grabstein, D. Cosman, and M. K. Spriggs. 1992. Molecular and biological characterization of a murine ligand for CD40. Nature 357:80.
9. Hollenbaugh, D., L. S. Grosmaire, C. D. Kullas, N. J. Chalupny, S. Braesch-Andersen, R. J. Noelle, I. Stamenkovic, J. A. Ledbetter, and A. Aruffo. 1992. The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity. EMBO J. 11:4313.
10. Gauchat, J. F., S. Henchoz, G. Mazzel, J. P. Aubry, T. Brunner, H. Blasey, P. Life, D. Tabalot, L. Flores-Romo, J. Thompson, K. Kishi, J. Butterfield, C. Dahinden, and J. Y. Bonnefoy. 1993. Induction of human IgE synthesis in B cells by mast cells and basophils. Nature 365:340.
11. Gauchat, J. F., S. Henchoz, D. Fattah, G. Mazzei, J. P. Aubry, T. Jomotte, L. Dash, K. Page, R. Solari, D. Aldebert, M. Capron, C. Dahinden, and J. Y. Bonnefoy. 1995. CD40 ligand is functionally expressed on human eosinophils. Eur. J. Immunol. 25:863.
12. Clark, E. A., and J. A. Ledbetter. 1994. How B and T cells talk to each other. Nature 367:425.
13. Noelle, R. J., J. A. Ledbetter, and A. Aruffo. 1992. CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation. Immunol. Today 13:431.
14. Allen, R. C., R. J. Armitage, M. E. Conley, H. Rosenblatt, N. A. Jenkins, N. G. Copeland, M. A. Bedell, S. Edelhoff, C. M. Disteche, D. K. Simoneaux, W. C. Fanslow, J. Belmont, and M. K. Spriggs. 1993. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science 259:990.
15. Aruffo, A., M. Farrington, D. Hollenbaugh, X. Li, A. Milatovich, S. Nonoyama, J. Bajorath, L. S. Grosmaire, R. Stenkamp, M. Neubauer, R. L. Roberts, R. J. Noelle, J. A. Ledbetter, U. Francke, and H. D. Ochs. 1993. The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. Cell 72:291.
16. Korthäuer, U., D. Graf, H. W. Mages, F. Brière, M. Padayachee, S. Malcolm, A. G. Ugazio, L. D. Notarangelo, R. J. Levinsky, and R. A. Kroczek. 1993. Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM. Nature 361:539.
17. Kiener, P. A., P. Moran-Davis, B. M. Rankin, A. F. Wahl, A. Aruffo, and D. Hollenbaugh. 1995. Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes. J. Immunol. 155:4917.
18. Caux, C., C. Massacrier, B. Vanbervliet, B. Dubois, C. van Kooten, I. Durand, and J. Banchereau. 1994. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180:1263.
19. Péguet-Navarro, J., C. Dalbiez-Gauthier, F. M. Rattis, C. van Kooten, J. Banchereau, and D. Schmitt. 1995. Functional expression of CD40 antigen on human epidermal Langerhans cells. J. Immunol. 155:4241.
20. Hess, S., A. Rensing-Ehl, R. Schwabe, P. Bufler, and H. Engelmann. 1995. CD40 function in nonhematopoietic cells: nuclear κB mobilization and induction of IL-6 production. J. Immunol. 155:4588.
21. Hollenbaugh, D., N. Mischel-Petty, C. P. Edwards, J. C. Simon, R. W. Denfeld, P. A. Kiener, and A. Aruffo. 1995. Expression of functional CD40 by vascular endothelial cells. J. Exp. Med. 182:33.
22. Karmann, K., C. C. W. Hughes, J. Schechner, W. C. Fanslow, and J. S. Pober. 1995. CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. Proc. Natl. Acad. Sci. USA 92:4342.
23. Yellin, M. J., J. Brett, D. Baum, A. Matsushima, M. Szaboles, D. Stern, and L. Chess. 1995. Functional interactions of T cells with endothelial cells: the role of CD40-CD40-L-mediated signal. J. Exp. Med. 182:1857.
24. Vallé, A., C. E. Zuber, T. Defrance, O. Djossou, M. de Rie, and J. Banchereau. 1989. Activation of human B lymphocytes through CD40 and interleukin 4. Eur. J. Immunol. 19:1463.
25. Garrone, P., E. M. Neidhardt, E. Garcia, L. Galibert, C. van Kooten, and J. Banchereau. 1995. Fas ligation induces apoptosis of CD40-activated human B lymphocytes. J. Exp. Med. 182:1265.
26. Jaffe, E. A., R. L. Nachman, C. G. Becker, and C. R. Minick. 1973. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J. Clin. Invest. 52:2745.
27. Taupin, J. L., N. Gualde, and J. F. Moreau. 1997. A monoclonal antibody based ELISA for quantitation of human leukemia inhibitory factor. Cytokine 9:112.
28. Grosset, C., B. Jazwiec, J. L. Taupin, H. Liu, S. Richard, F. X. Mahon, J. Reiffers, J. F. Moreau, and J. Ripoche. 1995. In vitro biosynthesis of leukemia inhibitory factor/human interleukin for DA cells by human endothelial cells: differential regulation by interleukin-1α and glucocorticoids. Blood 86:3763.
29. Cockerill, G. W., A. G. Bert, G. R. Ryan, J. R. Gamble, M. A. Vadas, and P. N. Cockerill. 1995. Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT. Blood 86:2689.
30. Banchereau, J., P. de Paoli, A. Vallé, E. Garcia, and F. Rousset. 1991. Long term human B cell lines dependent on interleukin 4 and antibody to CD40. Science 251:70.
31. Maier, J. A., D. Morelli, and A. Balsari. 1995. The differential response to interferon γ by normal and transformed endothelial cells. Biochem. Biophys. Res. Commun. 214:582.
32. Polunovskv, V. A., C. H. Wendt, D. H. Ingbar, M. S. Peterson, and P. B. Bitterman. 1994. Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis. Exp. Cell. Res. 214:584.
33. Liu, Y. J., D. E. Joshua, G. T. Williams, C. A. Smith, J. Gordon, and I. C. M. MacLennan. 1989. Mechanisms of antigen-driven selection in germinal centres. Nature 342:929.
34. Rissoan, M. C., C. van Kooten, P. Chomarat, L. Galibert, I. Durand, F. Thivolet-Bejui, P. Miossec, and J. Banchereau. 1996. The functional CD40 antigen of fibroblasts may contribute to the proliferation of rheumatoid synovium. Clin. Exp. Immunol. 106:481.
35. Déchanet, J., J. L. Taupin, P. Chomarat, M. C. Rissoan, J. F. Moreau, J. Banchereau, and P. Miossec. 1994. Production of leukemia inhibitory factor by rheumatoid synovium and synoviocytes: inhibition with interleukin 4. Eur. J. Immunol. 24:3222.
36. Howells, G., P. Pham, D. Taylor, B. Foxwell, and M. Feldman. 1991. Interleukin 4 induces interleukin 6 production by endothelial cells: synergy with interferon-γ. Eur. J. Immunol. 21:97.
37. Taupin, J. L., V. Pitard, J. Déchanet, V. Miossec, N. Gualde, and J. F. Moreau. 1996. Leukemia inhibitory factor: part of a large ingathering family. Int. Rev. Immunol. In press.
38. Burdin, N., K. van Kooten, L. Galibert, J. S. Abrams, J. Wijdenes, J. Banchereau, and F. Rousset. 1995. Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J. Immunol. 154:2533.
39. Mantovani, A., and E. Dejana. 1989. Cytokines as communication signals between leukocytes and endothelial cells. Immunol. Today 10:370.
40. Karmann, K., W. Min, W. C. Fanslow, and J. S. Pober. 1996. Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1. J. Exp. Med. 184:173.
41. Bentouimou, N., J. F. Moreau, M. A. Peyrat, J. P. Soulillou, and M. M. Hallet. 1993. The effects of cyclosporine on HILDA/LIF gene expression in human T cells. Transplantation 55:163.
42. Scheinman, R. I., P. C. Cogswell, A. K. Lofquist, and A. S. Baldwin. 1995. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 270:283.
43. Potocnik, A. J., R. Kinne, H. Menninger, J. Zacher, F. Emmrich, and R. A. Kroczek. 1990. Expression of activation antigens on T cells in rheumatoid arthritis patients. Scand. J. Immunol. 31:213.
44. Guerne, P. A., B. L. Zuraw, J. H. Vaughan, D. A. Carson, and M. Lotz. 1989. Synovium as a source of interleukin 6 in vitro: contribution to local and systemic manifestations of arthritis. J. Clin. Invest. 83:585.
45. Xu, W. D., G. S. Firestein, R. Taetle, K. Kaushansky, and N. J. Zvaifler. 1989. Cytokines in chronic inflammatory arthritis. IV. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions. J. Clin. Invest. 83:876.
46. + allogeneic vascular endothelium: identification of accessory interactions. Transplantation 56:128.
47. Pober, J. S., T. Collins, M. A. Gimbrone, R. S. Cotran, J. D. Gitlin, W. Fiers, C. Clayberger, A. M. Krensky, S. J. Burakoff, and C. S. Reiss. 1983. Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon. Nature 305:726.
48. + T cells through a CD2/LFA-3 signaling pathway. Eur. J. Immunol. 26:610.
49. van Kooten, C., C. Gaillard, J. P. Galizzi, P. Hermann, F. Fossiez, J. Banchereau, and D. Blanchard. 1994. B cells regulate expression of CD40-ligand on activated T cells by lowering the mRNA level and through the release of soluble CD40. Eur. J. Immunol. 24:787.
50. Mach, F., U. Schönbeck, G. K. Sukhova, T. Bourcier, J. Y. Bonnefoy, J. Pober, and P. Libby. 1997. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis. Proc. Natl. Acad. Sci. USA 94:1931.