In vitro-reduced susceptibility to artemether in p. falciparum and its association with polymorphisms on transporter genes

Journal of Infectious Diseases

Volumn 206, Issue 3, 2012, Pages 324-332

  Bustamante, Carolina ^a,b   Folarin, Onikepe A ^b,c   Gbotosho, Grace O ^b   Batista, Camila N ^a   Mesquita, Elieth A ^d   Brindeiro, Rodrigo M ^a   Tanuri, Amilcar ^a   Struchiner, Claudio J ^e   Sowunmi, Akintunde ^b   Oduola, Ayoade ^f   Wirth, Dyann F ^g   Zalis, Mariano G ^a   Happi, Christian T ^b,c,g  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF IBADAN   (Nigeria)

^c REDEEMER S UNIVERSITY   (Nigeria)

^d Centro de Pesquisas em Medicina Tropical de Rondônia   (Portugal)

^e INSTITUTO OSWALDO CRUZ   (Brazil)

^f WORLD HEALTH ORGANIZATION   (Switzerland)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMETHER; GENOMIC DNA; MULTIDRUG RESISTANCE PROTEIN 1; PLASMODIUM FALCIPARUM MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SUBSTITUTION; ANALYTICAL PARAMETERS; ANTIMALARIAL DRUG RESISTANCE; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; BIOASSAY; CHILD; CODON; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; GENE; GENE AMPLIFICATION; GENE DELETION; GENE FUNCTION; GENETIC ASSOCIATION; GEOMETRIC MEAN; HAPLOTYPE; HUMAN; IC 50; IN VITRO STUDY; MAJOR CLINICAL STUDY; NESTED POLYMERASE CHAIN REACTION; NIGERIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE ISOLATION; PF13 0271 GENE; PFCRT GENE; PFE0775C GENE; PFMDR1 GENE; PFMRP1 GENE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHIZONT INHIBITION ASSAY; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSPORTER GENE;

ANTIMALARIALS; ARTEMISININS; CARRIER PROTEINS; CHILD; DNA, PROTOZOAN; DRUG RESISTANCE; GENE EXPRESSION REGULATION; HUMANS; INHIBITORY CONCENTRATION 50; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROTOZOAN PROTEINS;

EID: 84863895349     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jis359     Document Type: Article

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