Mitochondrial tRNA mutations are associated with maternally inherited hypertension in two Han Chinese pedigrees

Human Mutation

Volumn 33, Issue 8, 2012, Pages 1285-1293

  Qiu, Qiaomeng ^a,b   Li, Ronghua ^c,d   Jiang, Pingping ^c   Xue, Ling ^b   Lu, Yang ^b   Song, Yaman ^b   Han, Jungang ^b   Lu, Zhongqiu ^a,b   Zhi, Shaoce ^a,b   Mo, Jun Qin ^d   Guan, Min Xin ^b,c,d  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Hypertension; Maternal inheritance; Mitochondria; Mutation; TRNA metabolism

Indexed keywords

MITOCHONDRIAL PROTEIN; MITOCHONDRIAL RNA; REACTIVE OXYGEN METABOLITE; TRANSFER RNA;

ADULT; AGED; ARTICLE; CHINESE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE MUTATION; GENETIC DISORDER; HUMAN; HUMAN CELL; HYPERTENSION; IN VIVO STUDY; MALE; MITOCHONDRIAL RESPIRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA METABOLISM;

ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME, MITOCHONDRIAL; HUMANS; HYPERTENSION; INHERITANCE PATTERNS; MALE; MIDDLE AGED; MUTATION; PEDIGREE; RNA, TRANSFER; YOUNG ADULT;

EID: 84863870567     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.22109     Document Type: Article

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