ADP-ribosylation factor 1 protein regulates trypsinogen activation via organellar trafficking of procathepsin B protein and autophagic maturation in acute pancreatitis

Journal of Biological Chemistry

Volumn 287, Issue 29, 2012, Pages 24284-24293

  Orlichenko, Lidiya ^a   Stolz, Donna B ^a   Noel, Pawan ^a   Behari, Jaideep ^a   Liu, Shiguang ^a   Singh, Vijay P ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PANCREATITIS; ADP-RIBOSYLATION; ADP-RIBOSYLATION FACTORS; AFFECT PROCESSING; AUTOPHAGOSOMES; AUTOPHAGY; CATHEPSIN B; DIGESTIVE ENZYMES; LIGHT CHAIN; SUBCELLULAR DISTRIBUTION; SUCROSE DENSITY GRADIENT CENTRIFUGATION;

CENTRIFUGATION; SUGAR (SUCROSE);

ELECTRON MICROSCOPY;

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 1; BREFELDIN A; CERULETIDE; PROCATHEPSIN B; PROTEIN PRECURSOR; SUCROSE; TRYPSINOGEN; UNCLASSIFIED DRUG;

ACUTE PANCREATITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL MATURATION; CELL ORGANELLE; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME REGULATION; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT;

ADP-RIBOSYLATION FACTOR 1; ANIMALS; AUTOPHAGY; BLOTTING, WESTERN; BREFELDIN A; CAERULEIN; CATHEPSIN B; ENZYME PRECURSORS; GOLGI APPARATUS; MICE; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; PANCREATITIS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; TRYPSINOGEN;

EID: 84863789599     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.328815     Document Type: Article

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