Controlled cortical impact traumatic brain injury acutely disrupts wakefulness and extracellular orexin dynamics as determined by intracerebral microdialysis in mice

Journal of Neurotrauma

Volumn 29, Issue 10, 2012, Pages 1908-1921

  Willie, Jon T ^a   Lim, Miranda M ^b   Bennett, Rachel E ^b   Azarion, Allan A ^b   Schwetye, Katherine E ^b   Brody, David L ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

circadian rhythm; electroencephalography; electromyography; hypocretin; hypothalamus; microdialysis; orexin; sleep; traumatic brain injury

Indexed keywords

OREXIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BIOLOGICAL MONITORING; BRAIN CONTUSION; BRAIN CORTEX; BRAIN PERFUSION; CATHETER; CIRCADIAN RHYTHM; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; ELECTROMAGNETIC FIELD; ELECTROMYOGRAPHY; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; INFORMATION PROCESSING; INTERSTITIAL FLUID; MALE; MICRODIALYSIS; MOTOR ACTIVITY; MOUSE; NONHUMAN; SHAM PROCEDURE; SLEEP WAKING CYCLE; TRAUMATIC BRAIN INJURY;

ACUTE DISEASE; ANIMALS; BRAIN INJURIES; CEREBRAL CORTEX; CONSCIOUSNESS DISORDERS; DISEASE MODELS, ANIMAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICRODIALYSIS; NEUROPEPTIDES; WAKEFULNESS;

EID: 84863788057     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2012.2404     Document Type: Article

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