Mitochondrial single nucleotide polymorphism genotyping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using cleavable biotinylated dideoxynucleotides

Analytical Biochemistry

Volumn 427, Issue 2, 2012, Pages 202-210

  Qiu, Chunmei ^a,b   Kumar, Shiv ^a,b   Guo, Jia ^a,b   Lu, Jiesheng ^a   Shi, Shundi ^a,b   Kalachikov, Sergey M ^a,b   Russo, James J ^a,b   Naini, Ali B ^a   Schon, Eric A ^a   Ju, Jingyue ^a,b  

^a College of Physicians and Surgeons ^*  (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cleavable biotinylated dideoxynucleotides; Genotyping; MALDI TOF MS; Mitochondrial DNA; Single base extension; Single nucleotide polymorphism; Solid phase capture

Indexed keywords

DESALINATION; DESORPTION; DIAGNOSIS; DNA; MITOCHONDRIA; NUCLEOTIDES; POLYMORPHISM;

CLEAVABLE BIOTINYLATED DIDEOXYNUCLEOTIDES; GENOTYPING; MALDI TOF MS; MITOCHONDRIAL DNA; SINGLE NUCLEOTIDE POLYMORPHISMS; SINGLE-BASE EXTENSIONS; SOLID-PHASE;

MASS SPECTROMETRY;

DIDEOXYNUCLEOTIDE; MITOCHONDRIAL DNA;

ARTICLE; DNA DETERMINATION; GENE MUTATION; GENOTYPE; HUMAN; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MERRF SYNDROME; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION STUDY;

EID: 84863780628     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.05.001     Document Type: Article

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