Targeted gene delivery to hepatocytes with galactosylated amphiphilic cyclodextrins

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 8, 2012, Pages 1063-1073

  McMahon, Anthony ^a   O'Neill, Martin J ^b   Gomez, Eva ^c   Donohue, Ruth ^d   Forde, Damien ^e   Darcy, Raphael ^d   O'Driscoll, Caitriona M ^b  

^a Azur Pharma Ltd   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^d UNIVERSITY COLLEGE DUBLIN   (Ireland)

^e Kinerton Ltd   (Ireland)

Author keywords

Cyclodextrins; Gene delivery; Intracellular targeting; Trafficking

Indexed keywords

AMPHOPHILE; ASIALOGLYCOPROTEIN RECEPTOR; CATION; CYCLODEXTRIN DERIVATIVE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; GALACTOSE; LECTIN; LUCIFERASE; PLASMID DNA;

ARTICLE; CELL STRAIN HEPG2; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG BINDING; DRUG FORMULATION; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ASSAY; GENE DELIVERY SYSTEM; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LECTIN BINDING; LIVER CELL; SURFACE PLASMON RESONANCE;

ASIALOGLYCOPROTEIN RECEPTOR; CATIONS; CYCLODEXTRINS; DNA; GALACTOSE; GENE TARGETING; GENETIC THERAPY; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LECTINS; LIPIDS; LUCIFERASES; MICROSCOPY, CONFOCAL; PHOSPHATIDYLETHANOLAMINES; PLASMIDS; TRANSFECTION;

EID: 84863721118     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01497.x     Document Type: Article

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