Potential factors influencing the development of thrombocytopenia and consumptive coagulopathy after genetically modified pig liver xenotransplantation

Transplant International

Volumn 25, Issue 8, 2012, Pages 882-896

  Ekser, Burcin ^a,b   Lin, Chih C ^a,c   Long, Cassandra ^a   Echeverri, Gabriel J ^a,d   Hara, Hidetaka ^a   Ezzelarab, Mohamed ^a   Bogdanov, Vladimir Y ^e   Stolz, Donna B ^f   Enjyoji, Keiichi ^g   Robson, Simon C ^g   Ayares, David ^h   Dorling, Anthony ⁱ   Cooper, David K C ^a   Gridelli, Bruno ^a,d  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF CATANIA   (Italy)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d MEDITERRANEAN INSTITUTE FOR TRANSPLANTATION AND ADVANCED SPECIALIZED THERAPIES ISMETT   (Italy)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^g HARVARD MEDICAL SCHOOL   (United States)

^h REVIVICOR INC   (United States)

ⁱ GUY S HOSPITAL   (United Kingdom)

Author keywords

baboon; consumptive coagulopathy; genetically engineered; liver transplantation; pig; tissue factor; xenotransplantation

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; CYCLOPHOSPHAMIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; SNAKE VENOM; TACROLIMUS; THROMBIN; THROMBOPLASTIN; THYMOCYTE ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BABOON; CONTROLLED STUDY; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; DNA MODIFICATION; ENDOTHELIAL MICROPARTICLE; ENDOTHELIUM CELL; GENE INACTIVATION; IMMUNOSUPPRESSIVE TREATMENT; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MICROPARTICLE ENZYME IMMUNOASSAY; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REPERFUSION; SWINE; THROMBOCYTE; THROMBOCYTOPENIA; XENOTRANSPLANTATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL-DERIVED MICROPARTICLES; DISSEMINATED INTRAVASCULAR COAGULATION; GALACTOSYLTRANSFERASES; PAPIO; SUS SCROFA; THROMBOCYTOPENIA; THROMBOPLASTIN; TRANSPLANTATION, HETEROLOGOUS;

EID: 84863718470     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2012.01506.x     Document Type: Article

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