Activation of human platelets by the membrane-expressed A1 domain of von Willebrand factor

Blood

Volumn 90, Issue 11, 1997, Pages 4425-4437

  Schulte Am Esch II, Jan ^a   Cruz, Miguel A ^b   Siegel, Jonathan B ^b   Anrather, Josef ^b   Robson, Simon C ^b  

^a Immunobiology Research Center   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL; HYBRID PROTEIN; RISTOCETIN; THROMBOCYTE ACTIVATING FACTOR; VON WILLEBRAND FACTOR;

ARTICLE; CALCIUM CELL LEVEL; GENE EXPRESSION; GRAFT REJECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; SHEAR STRESS; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOGENESIS;

EID: 1842373352     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.11.4425.4425_4425_4437     Document Type: Article

References (59)

1. Bach FH, Winkler H, Ferran C, Hancock WW, Robson SC: Delayed xenograft rejection. Immunol Today 17:379, 1996 (review)
2. Makowka L, Chapman FA, Cramer DV, Qian SG, Sun H, Starzl TE: Platelet-activating factor and hyperacute rejection. The effect of a platelet-activating factor antagonist, SRI 63-441, on rejection of xenografts arid allografts in sensitized hosts. Transplantation 50:359, 1990
3. Coughlan AF, Berndt MC, Dunlop LC, Hancock WW: In vivo studies of P-selectin and platelet activating factor during endotoxemia, accelerated allograft rejection, discordant xenograft rejection. Transplant Proc 25:2930, 1993
4. Candinas D, Lesnikoski BA, Hancock WW, Otsu I, Koyamada N, Dalmasso AP, Robson SC, Bach FH: Inhibition of platelet integrin GPIIbIIIa prolongs survival of discordant cardiac xenografts. Transplantation 62:1, 1996
5. Young VK, Kaspar-Konig W, Tew DN, Wallwork J, White DJ, Pierson RN III: White blood cells and platelets are integral to the hyperacute rejection of the pig heart by human blood. Transplant Proc 27:272, 1995
6. Robson SR, Young VK, Cook NS, Kottirsch G, Siegel JB, Lesnikoski BA, Candinas D, White DJG, Bach FH: Inhibition of platelet GPIIbIIIa in an ex vivo model of hyperacute xenograft rejection does not prolong cardiac survival time. Xenotransplantation 3:43, 1996
7. Girma JP, Meyer D, Verweij CL, Pannekoek H, Sixma JJ: Structure-function relationship of human von Willebrand factor. Blood 70:605, 1987 (review)
8. Turitto VT, Weiss HJ, Zimmerman TS, Sussman II: Factor VIII/von Willebrand factor in subendothelium mediates platelet adhesion. Blood 65:823, 1985
9. Peterson DM, Stathopoulos NA, Giorgio TD, Heliums JD, Moake JL: Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa. Blood 69:625, 1987
10. Kawakami K, Fukuyama M, Sakai K, Itagaki I, Kawano K, Handa M, Ikeda Y: Change in intracellular calcium ions during shear induced platelet aggregation. ASAIO Trans 36:M696, 1990
11. Fressinaud E, Meyer D: von Willebrand factor and platelet interactions with the vessel wall. Blood Coagul Fibrinolysis 2:333, 1991 (review)
12. Verweij CL, Diergaarde PJ, Hart M, Pannekoek H: Fulllength von Willebrand factor (vWF) cDNA encodes a highly repetitive protein considerably larger than the mature vWF subunit [published erratum appears in EMBO J 5:3074, 1986]. EMBO J 5:1839, 1986
13. Ruggeri ZM: Von Willebrand factor as a target for antithrombotic intervention [see comments]. Circulation 86:11126, 1992 (review, suppl)
14. Andrews RK, Gorman JJ, Booth WJ, Corino GL, Castaldi PA, Berndt MC: Cross-linking of a monomeric 39/34-kDa dispase fragment of von Willebrand factor (Leu-480/Val-481-Gly-718) to the n-terminal region of the α-chain of membrane glycoprotein Ib on intact platelets with bis (sulfosuccinimidyl) subarate. Biochemistry 28:8326, 1989
15. Fujimura Y, Titani K, Holland LZ, Russell SR, Roberts JR, Elder JH, Ruggeri ZM, Zimmerman TS: von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib. J Biol Chem 261:381, 1986
16. Matsushita T, Sadler JE: Identification of amino acid residues essential for von Willebrand factor binding to platelet glycoprotein Ib. Charged-to-alanine scanning mutagenesis of the A1 domain of human von Willebrand factor. J Biol Chem 270:13406, 1995
17. Pietu G, Meulien P, Cherel G, Diaz J, Baruch D, Courtney M, Meyer D: Production in Escherichia coli of a biologically active subfragment of von Willebrand factor corresponding to the platelet glycoprotein Ib, collagen and heparin binding domains. Biochem Biophys Res Comm 164:1339, 1989
18. Cruz MA, Handin RI, Wise RJ: The interaction of the von Willebrand factor-A1 domain with platelet glycoprotein Ib/IX. The role of glycosylation and disulfide bonding in a monomeric recombinant A1 domain protein. J Biol Chem 268:21238, 1993
19. Cruz MA, Yuan H, Lee JR, Wise RJ, Handin RI: Interaction of the von Willebrand factor (vWF) with collagen. Localization of the primary collagen-binding site by analysis of recombinant vWF a domain polypeptides [published erratum appears in J Biol Chem 270:19668, 1995]. J Biol Chem 270:10822, 1995
20. Miyata S, Goto S, Federici AB, Ware J, Ruggeri ZM: Conformational changes in the A1 domain of von Willebrand factor modulating the interaction with platelet glycoprotein Ib alpha. J Biol Chem 271:9046, 1996
21. Brinkhous KM: Animal models: Importance in research on hemorrhage and thrombosis. Adv Exp Med Biol 102:123, 1978 (review)
22. Evans RJ, Austen DE: Assay and characterization of the factor in porcine and bovine plasma which aggregates human platelets. Br J Haematol 36:117, 1977
23. Saniabadi AR, Marney Y, Belch JJ, Lowe GD, Barbenel JC, Madhok R, Forbes CD: Further evidence that the residual vWf:Ag in porcine FVIII:C induces human platelet aggregation. Haemostasis 20:289, 1990
24. Altieri DC, Capitanio AM, Mannucci PM: von Willebrand factor contaminating porcine factor VIII concentrate (Hyate:C) causes platelet aggregation. Br J Haematol 63:703, 1986
25. Lozier JN, Santagostino E, Kasper CK, Teitel JM, Hay CR: Use of porcine factor VIII for surgical procedures in hemophilia A patients with inhibitors. Semin Hematol 30:10, 1993 (suppl 1)
26. Pareti FI, Mazzucato M, Bottini E, Mannucci PM: Interaction of porcine von Willebrand factor with the platelet glycoproteins Ib and IIb/IIIa complex. Br J Haematol 82:81, 1992
27. Mazzucato M, De Marco L, Pradella P, Masotti A, Pareti FI: Porcine von Willebrand Factor binding to human platelet GPIb induces transmembrane calcium influx. Thromb Haemost 75:655, 1996
28. De Marco L, Shapiro SS: Properties of human asialo-factor VIII. A ristocetin-independent platelet-aggregating agent. J Clin Invest 68:321, 1981
29. De Marco L, Girolami A, Russell S, Ruggeri ZM: Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation. J Clin Invest 75:1198, 1985
30. Grainick HR, Williams SB, Coller BS: Asialo von Willebrand factor interactions with platelets. Interdependence of glycoproteins Ib and IIb/IIIa for binding and aggregation. J Clin Invest 75:19, 1985
31. 2+ concentration. Thromb Haemost 70:697, 1993
32. Ruggeri ZM, Pareti FI, Mannucci PM, Ciavarella N, Zimmerman TS: Heightened interaction between platelets and factor VIII/ von Willebrand factor in a new subtype of von Willebrand's disease. N Engl J Med 302:1047, 1980
33. Ribba AS, Voorberg J, Meyer D, Pannekoek H, Pietu G: Characterization of recombinant von Willebrand factor corresponding to mutations in type HA and type IIB von Willebrand disease. J Biol Chem 267:23209, 1992
34. Caras IW, Weddell GN: Signal peptide for protein secretion directing glycophospholipid membrane anchor attachment. Science 243:1196, 1989
35. Paborsky LR, Caras IW, Fisher KL, German CM: Lipid association, but not the transmembrane domain, is required for tissue factor activity. Substitution of the transmembrane domain with a phosphatidylinositol anchor. J Biol Chem 266:21911, 1991
36. Coller BS, Peerschke EI, Scudder LE, Sullivan CA: Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: Additional evidence in support of GPIb as a platelet receptor for von Willebrand factor. Blood 61:99, 1983
37. Coller BS: A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex. J Clin Invest 76:101, 1985
38. Mohri H, Fujimura Y, Shima M, Yoshihiro A, Houghten RA, Ruggeri ZM, Zimmerman TS: Structure of the von Willebrand Factor domain interacting with glycoprotein Ib. J Biol Chem 263:17901, 1988
39. Bonthron D, Orr EC, Mitsock LM, Ginsburg D, Handin RI, Orkin SH: Nucleotide sequence of pre-pro-von Willebrand factor cDNA. Nucleic Acids Res 14:7125, 1986
40. Bahnak BR, Lavergne JM, Ferreira V, Kerbiriou-Nabias D, Meyer D: Comparison of the primary structure of the functional domains of human and porcine von Willebrand factor that mediate platelet adhesion. Biochem Biophys Res Comm 182:561, 1992
41. Chubet RG, Brizzard BL: Vectors for expression and secretion of FLAG epitope-tagged proteins in mammalian cells. Biotechniques 20:136, 1996
42. Goto S, Salomon DR, Ikeda Y, Ruggeri ZM: Characterization of the unique mechanism mediating the shear-dependent binding of soluble von Willebrand factor to platelets. J Biol Chem 270:23352, 1995
43. Cooper MB, Tan KC, Betteridge DJ: Platelet transmembrane signalling responses to collagen in familial hypercholesterolaemia. Eur J Clin Invest 24:737, 1994
44. Peerschke EI: The platelet fibrinogen receptor. Semin Hematol 22:241, 1985 (review)
45. Yamaguchi A, Suzuki H, Tanoue K, Yamazaki H: Simple method of aequorin loading into platelets using dimethyl sulfoxide. Thromb Res 44:165, 1986
46. Siess W: Molecular mechanisms of platelet activation. Physiol Rev 69:58, 1989 (review)
47. Bakhshi MR, Myers JC, Howard PS, Soprano DR, Kirby EP: Sequencing of the primary adhesion domain of bovine von Willebrand factor. Biochim Biophys Acta 1132:325, 1992
48. Ikeda Y, Handa M, Kamata T, Kawano K, Kawai Y, Watanabe K, Kawakami K, Sakai K, Fukuyama M, Itagaki I: Transmembrane calcium influx associated with von Willebrand factor binding to GPIb in the initiation of shear-induced platelet aggregation. Thromb Haemost 69:496, 1993
49. Federici AB, Bader R, Pagani S, Colibretti ML, De Marco L, Mannucci PM: Binding of von Willebrand factor to glycoproteins Ib and IIb/IIIa complex: Affinity is related to multimeric size. Br J Haematol 73:93, 1989
50. Ruggeri ZM, Mannucci PM, Lombardi R, Federici AB, Zimmerman TS: Multimeric composition of factor VIII/von Willebrand factor following administration of DDAVP: Implications for patho-physiology and therapy of von Willebrand's disease subtypes. Blood 59:1272, 1982
51. Ruggeri ZM: von Willebrand factor and fibrinogen. Curr Opin Cell Biol 5:898, 1993 (review)
52. Weiss HJ, Pietu G, Rabinowitz R, Girma JP, Rogers J, Meyer D: Heterogeneous abnormalities in the multimeric structure, antigenic properties, plasma-platelet content of factor VIII/von Willebrand factor in subtypes of classic (type I) and variant (type IIA) von Willebrand's disease. J Lab Clin Med 101:411, 1983
53. Brinkhous KM, Thomas BD, Ibrahim SA, Read MS: Plasma levels of platelet aggregating factor/von Willebrand factor in various species. Thromb Res 11:345, 1977
54. Forbes CD, Barr RD, McNicol GP, Douglas AS: Aggregation of human platelets by commercial preparations of bovine and porcine antihaemophilic globulin. J Clin Pathol 25:210, 1972
55. Finlay TH, Marcus DL, Kowalski S, Silber P: Interaction of porcine von Willebrand factor (platelet aggregating factor) with human platelets. Biochim Biophys Acta 672:79, 1981
56. Meyer D, Pietu G, Fressinaud E, Girma JP: Von Willebrand factor: structure and function. Mayo Clin Proc 66:516, 1991 (review)
57. Siedlecki CA, Lestini BJ, Kottke-Marchant K, Eppel SJ, Wilson DL, Marchant RE: Shear stress-dependent changes in the three-dimensional structure of human von Willebrand factor. Blood 88:2939, 1996
58. Gralnick HR, Williams S, McKeown L, Kramer W, Krutzsch H, Gorecki M, Pinet A, Garfinkel LI: A monomeric von Willebrand factor fragment, Leu-504 - Lys-728, inhibits von Willebrand factor interaction with glycoprotein Ib-IX [corrected] [published erratum appears in Proc Natl Acad Sci USA 90:3118, 1993]. Proc Natl Acad Sci USA 89:7880, 1992
59. Zahger D, Fishbein MC, Garfinkel LI, Shah PK, Forrester JS, Regnstrom J, Yano J, Cercek B: VCL, an antagonist of the platelet GPIb receptor, markedly inhibits platelet adhesion and intimai thickening after balloon injury in the rat. Circulation 92:1269, 1995