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Volumn 7, Issue 1, 2012, Pages

Genetically-engineered pig-to-baboon liver xenotransplantation: Histopathology of xenografts and native organs

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4D; COMPLEMENT MEMBRANE ATTACK COMPLEX; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; GALACTOSYLTRANSFERASE; N ACETYLLACTOSAMINIDE ALPHA 1,3 GALACTOSYLTRANSFERASE; N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE;

EID: 84855682133     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029720     Document Type: Article
Times cited : (33)

References (31)
  • 1
    • 72949090557 scopus 로고    scopus 로고
    • Pig liver xenotransplantation as a bridge to allotransplantation: which patients might benefit?
    • Ekser B, Gridelli B, Tector AJ, Cooper DKC, (2009) Pig liver xenotransplantation as a bridge to allotransplantation: which patients might benefit? Transplantation 88: 1041-1049.
    • (2009) Transplantation , vol.88 , pp. 1041-1049
    • Ekser, B.1    Gridelli, B.2    Tector, A.J.3    Cooper, D.K.C.4
  • 2
    • 0347367029 scopus 로고    scopus 로고
    • Production of α1,3-galactosyltransferase-deficient pigs
    • Phelps CJ, Koike C, Vaught TD, Boone J, Wells KD, et al. (2003) Production of α1,3-galactosyltransferase-deficient pigs. Science 299: 411-414.
    • (2003) Science , vol.299 , pp. 411-414
    • Phelps, C.J.1    Koike, C.2    Vaught, T.D.3    Boone, J.4    Wells, K.D.5
  • 3
    • 0029068597 scopus 로고
    • The generation of transgenic pigs as potential organ donors for humans
    • Cozzi E, White DJ, (1995) The generation of transgenic pigs as potential organ donors for humans. Nat Med 1: 964-966.
    • (1995) Nat Med , vol.1 , pp. 964-966
    • Cozzi, E.1    White, D.J.2
  • 4
    • 10744224843 scopus 로고    scopus 로고
    • Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons
    • Loveland BE, Milland J, Kyriakou P, Thorley BR, Christiansen D, et al. (2004) Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons. Xenotransplantation 11: 171-183.
    • (2004) Xenotransplantation , vol.11 , pp. 171-183
    • Loveland, B.E.1    Milland, J.2    Kyriakou, P.3    Thorley, B.R.4    Christiansen, D.5
  • 5
    • 13444269248 scopus 로고    scopus 로고
    • Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue
    • Yamada K, Yazawa K, Shimizu A, Iwanaga T, Hisashi Y, et al. (2005) Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue. Nat Med 11: 32-34.
    • (2005) Nat Med , vol.11 , pp. 32-34
    • Yamada, K.1    Yazawa, K.2    Shimizu, A.3    Iwanaga, T.4    Hisashi, Y.5
  • 6
    • 13444282227 scopus 로고    scopus 로고
    • Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: initial experience
    • Kuwaki K, Tseng YL, Dor FJ, Shimizu A, Houser SL, et al. (2005) Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med 11: 29-31.
    • (2005) Nat Med , vol.11 , pp. 29-31
    • Kuwaki, K.1    Tseng, Y.L.2    Dor, F.J.3    Shimizu, A.4    Houser, S.L.5
  • 7
    • 44849144688 scopus 로고    scopus 로고
    • Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from α1,3-galactosyltransferase gene-knockout pigs in baboons
    • Shimizu A, Hisashi Y, Kuwaki K, Tseng Y-L, Dor FJMF, et al. (2008) Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from α1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol 172: 1471-1481.
    • (2008) Am J Pathol , vol.172 , pp. 1471-1481
    • Shimizu, A.1    Hisashi, Y.2    Kuwaki, K.3    Tseng, Y.-L.4    Dor, F.J.M.F.5
  • 8
    • 65549162661 scopus 로고    scopus 로고
    • The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients
    • Ezzelarab M, Garcia B, Azimzadeh A, Sun H, Lin CC, et al. (2009) The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients. Transplantation 87: 805-812.
    • (2009) Transplantation , vol.87 , pp. 805-812
    • Ezzelarab, M.1    Garcia, B.2    Azimzadeh, A.3    Sun, H.4    Lin, C.C.5
  • 9
    • 79954575125 scopus 로고    scopus 로고
    • Over six month survival of cardiac xenograft is achievable but heterotopic placement of the graft may limit consistent prolonged survival. (Abstract TTS-1383)
    • Mohiuddin MM, Corcoran PC, Singh AK, Azimzadeh AM, Hoyt RF, et al. (2010) Over six month survival of cardiac xenograft is achievable but heterotopic placement of the graft may limit consistent prolonged survival. (Abstract TTS-1383). Transplantation 90 (suppl): 325.
    • (2010) Transplantation , vol.90 , Issue.SUPPL. , pp. 325
    • Mohiuddin, M.M.1    Corcoran, P.C.2    Singh, A.K.3    Azimzadeh, A.M.4    Hoyt, R.F.5
  • 10
    • 42149121373 scopus 로고    scopus 로고
    • Liver xenografts for the treatment of acute liver failure: clinical and experimental experience and remaining immunologic barriers
    • Hara H, Gridelli B, Lin YJ, Marcos A, Cooper DKC, (2008) Liver xenografts for the treatment of acute liver failure: clinical and experimental experience and remaining immunologic barriers. Liver Transpl 14: 425-434.
    • (2008) Liver Transpl , vol.14 , pp. 425-434
    • Hara, H.1    Gridelli, B.2    Lin, Y.J.3    Marcos, A.4    Cooper, D.K.C.5
  • 11
    • 79959750277 scopus 로고    scopus 로고
    • Clinical pig liver xenotransplantation: how far do we have to go?
    • Ekser B, Gridelli B, Veroux M, Cooper DKC, (2011) Clinical pig liver xenotransplantation: how far do we have to go? Xenotransplantation 18: 158-167.
    • (2011) Xenotransplantation , vol.18 , pp. 158-167
    • Ekser, B.1    Gridelli, B.2    Veroux, M.3    Cooper, D.K.C.4
  • 12
    • 0034668088 scopus 로고    scopus 로고
    • Life-supporting human complement regulator decay accelerating factor transgenic pig liver xenograft maintains the metabolic function and coagulation in the nonhuman primate for up to 8 days
    • Ramirez P, Chavez R, Majado M, Munitiz V, Muñoz A, et al. (2000) Life-supporting human complement regulator decay accelerating factor transgenic pig liver xenograft maintains the metabolic function and coagulation in the nonhuman primate for up to 8 days. Transplantation 70: 989-998.
    • (2000) Transplantation , vol.70 , pp. 989-998
    • Ramirez, P.1    Chavez, R.2    Majado, M.3    Munitiz, V.4    Muñoz, A.5
  • 13
    • 29544445657 scopus 로고    scopus 로고
    • Prevention of hyperacute rejection in a model of orthotopic liver xenotransplantation from pig to baboon using polytransgenic pig livers (CD55, CD59, and H-transferase)
    • Ramirez P, Montoya MJ, Ríos A, García Palenciano C, et al. (2005) Prevention of hyperacute rejection in a model of orthotopic liver xenotransplantation from pig to baboon using polytransgenic pig livers (CD55, CD59, and H-transferase). Transplant Proc 37: 4103-4106.
    • (2005) Transplant Proc , vol.37 , pp. 4103-4106
    • Ramirez, P.1    Montoya, M.J.2    Ríos, A.3    García Palenciano, C.4
  • 14
    • 75149191343 scopus 로고    scopus 로고
    • Impact of thrombocytopenia on survival of baboons with genetically-modified pig liver transplants: clinical relevance
    • Ekser B, Long C, Echeverri GJ, Hara H, Ezzelarab M, et al. (2010) Impact of thrombocytopenia on survival of baboons with genetically-modified pig liver transplants: clinical relevance. Am J Transplant 10: 273-285.
    • (2010) Am J Transplant , vol.10 , pp. 273-285
    • Ekser, B.1    Long, C.2    Echeverri, G.J.3    Hara, H.4    Ezzelarab, M.5
  • 15
    • 1642593877 scopus 로고
    • Histopathology of liver xenograft rejection
    • In: Cooper DKC, Kemp E, Reemtsma K, White DJG, editors, Heidelberg, Germany, Springer 1991
    • Wight DGD, (1991) Histopathology of liver xenograft rejection. In: Cooper DKC, Kemp E, Reemtsma K, White DJG, editors. Xenotransplantation pp. 253-272 Heidelberg, Germany, Springer 1991.
    • (1991) Xenotransplantation , pp. 253-272
    • Wight, D.G.D.1
  • 17
    • 0027399515 scopus 로고
    • Immunopathology of liver allografts and xenografts in nonhuman primates
    • Donato MF, Arosio E, Berti E, Gatti S, Piazzini A, et al. (1993) Immunopathology of liver allografts and xenografts in nonhuman primates: Transplant Proc 25: 850-855.
    • (1993) Transplant Proc , vol.25 , pp. 850-855
    • Donato, M.F.1    Arosio, E.2    Berti, E.3    Gatti, S.4    Piazzini, A.5
  • 19
    • 13144278323 scopus 로고    scopus 로고
    • Comparative histology of hepatic allografts and xenografts in the nonhuman primate
    • Luo T, Kosanke S, Mieles L, Kobayashi T, Li SF, et al. (1998) Comparative histology of hepatic allografts and xenografts in the nonhuman primate. Xenotransplantation 5: 197-206.
    • (1998) Xenotransplantation , vol.5 , pp. 197-206
    • Luo, T.1    Kosanke, S.2    Mieles, L.3    Kobayashi, T.4    Li, S.F.5
  • 20
    • 33644793661 scopus 로고    scopus 로고
    • Harmful delayed effects of exogenous isolation enzymes on isolated human islets: relevance to clinical transplantation
    • Balamurugan AN, He J, Guo F, Stolz DB, Bertera S, et al. (2005) Harmful delayed effects of exogenous isolation enzymes on isolated human islets: relevance to clinical transplantation. Am J Transplant 5: 2671-2681.
    • (2005) Am J Transplant , vol.5 , pp. 2671-2681
    • Balamurugan, A.N.1    He, J.2    Guo, F.3    Stolz, D.B.4    Bertera, S.5
  • 21
    • 0035144232 scopus 로고    scopus 로고
    • Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver
    • Wack KE, Ross MA, Zegarra V, Sysko LR, Watkins SC, et al. (2001) Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver. Hepatology 33: 363-378.
    • (2001) Hepatology , vol.33 , pp. 363-378
    • Wack, K.E.1    Ross, M.A.2    Zegarra, V.3    Sysko, L.R.4    Watkins, S.C.5
  • 22
    • 78349272828 scopus 로고    scopus 로고
    • The fate of human platelets perfused through the pig liver: implications for xenotransplantation
    • Burlak C, Paris LL, Chihara RK, Sidner RA, Reyes LM, et al. (2010) The fate of human platelets perfused through the pig liver: implications for xenotransplantation. Xenotransplantation 17: 350-361.
    • (2010) Xenotransplantation , vol.17 , pp. 350-361
    • Burlak, C.1    Paris, L.L.2    Chihara, R.K.3    Sidner, R.A.4    Reyes, L.M.5
  • 23
    • 83755188441 scopus 로고    scopus 로고
    • Integrin-dependent baboon platelet activation and phagocytosis by porcine hepatocytes and endothelial cells. (Abstract-394)
    • Peng Q, Yeh H, Enjoji K, Machaidze Z, Wei L, et al. (2011) Integrin-dependent baboon platelet activation and phagocytosis by porcine hepatocytes and endothelial cells. (Abstract-394). Xenotransplantation 18: 287-288.
    • (2011) Xenotransplantation , vol.18 , pp. 287-288
    • Peng, Q.1    Yeh, H.2    Enjoji, K.3    Machaidze, Z.4    Wei, L.5
  • 24
    • 78349232839 scopus 로고    scopus 로고
    • An in vitro model of pig liver xenotransplantation-pig complement is associated with reduced lysis of wild-type and genetically modified pig cells
    • Hara H, Campanile N, Tai HC, Long C, Ekser B, et al. (2010) An in vitro model of pig liver xenotransplantation-pig complement is associated with reduced lysis of wild-type and genetically modified pig cells. Xenotransplantation 17: 370-378.
    • (2010) Xenotransplantation , vol.17 , pp. 370-378
    • Hara, H.1    Campanile, N.2    Tai, H.C.3    Long, C.4    Ekser, B.5
  • 26
    • 39149104044 scopus 로고    scopus 로고
    • The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity
    • Elvevold K, Smedsrod B, Martinez I, (2008) The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity: Am J Physiol Gastrointest Liver Physiol 294: G391-400.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Elvevold, K.1    Smedsrod, B.2    Martinez, I.3
  • 27
  • 28
    • 77955865098 scopus 로고    scopus 로고
    • CD47 in xenograft rejection and tolerance induction
    • Yang YG, (2010) CD47 in xenograft rejection and tolerance induction. Xenotransplantation 17: 267-273.
    • (2010) Xenotransplantation , vol.17 , pp. 267-273
    • Yang, Y.G.1
  • 29
    • 55649120266 scopus 로고    scopus 로고
    • In vitro investigation of pig cells for resistance to human antibody-mediated rejection
    • Hara H, Long C, Lin YJ, Tai HC, Ezzelarab M, et al. (2008) In vitro investigation of pig cells for resistance to human antibody-mediated rejection. Transpl Int 21: 1163-1174.
    • (2008) Transpl Int , vol.21 , pp. 1163-1174
    • Hara, H.1    Long, C.2    Lin, Y.J.3    Tai, H.C.4    Ezzelarab, M.5
  • 30
    • 84862955450 scopus 로고    scopus 로고
    • The use of non-human primates in research - The Weatherall Report
    • Weatherall D, (2006) pp. 1-153 The use of non-human primates in research- The Weatherall Report.
    • (2006) , pp. 1-153
    • Weatherall, D.1
  • 31
    • 85041813459 scopus 로고    scopus 로고
    • Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
    • Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG, (2010) Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research. PLoS Biol 8: e1000412.
    • (2010) PLoS Biol , vol.8
    • Kilkenny, C.1    Browne, W.J.2    Cuthill, I.C.3    Emerson, M.4    Altman, D.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.