Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE

Epilepsia

Volumn 53, Issue 7, 2012, Pages 1233-1244

  Jupp, Bianca ^a   Williams, John ^b   Binns, David ^c   Hicks, Rodney J ^c   Cardamone, Lisa ^a   Jones, Nigel ^a   Rees, Sandra ^a   O'Brien, Terence J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

Epileptogenesis; Fluorodeoxyglucose positron emission tomography; MRI; Post kainic acid status epilepticus; Temporal lobe epilepsy

Indexed keywords

CYTOCHROME C OXIDASE; FLUORODEOXYGLUCOSE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE TRANSPORTER 1; KAINIC ACID; SYNAPTOPHYSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTOSIS; BRAIN ATROPHY; BRAIN METABOLISM; CELL LOSS; CONTROLLED STUDY; DISEASE SEVERITY; ENERGY METABOLISM; EPILEPTIC STATE; EPILEPTOGENESIS; HISTOLOGY; IN VIVO STUDY; LIMBIC ATROPHY; LIMBIC SYSTEM; MALE; METABOLIC DISORDER; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYNAPTOGENESIS; TEMPORAL HYPOMETABOLISM; TEMPORAL LOBE EPILEPSY;

ANALYSIS OF VARIANCE; ANIMALS; ATROPHY; BRAIN MAPPING; CA1 REGION, HIPPOCAMPAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELECTROENCEPHALOGRAPHY; ELECTRON TRANSPORT COMPLEX IV; EPILEPSY, TEMPORAL LOBE; EXCITATORY AMINO ACID AGONISTS; FLUORODEOXYGLUCOSE F18; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE METABOLISM DISORDERS; GLUCOSE TRANSPORTER TYPE 1; KAINIC ACID; LIMBIC SYSTEM; MAGNETIC RESONANCE IMAGING; MALE; POSITRON-EMISSION TOMOGRAPHY; PYRAMIDAL CELLS; RATS; RATS, WISTAR; SYNAPTOPHYSIN; TIME FACTORS;

EID: 84863717622     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2012.03525.x     Document Type: Article

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