A retrospective analysis of hippocampal pathology in human temporal lobe epilepsy: Evidence for distinctive patient subcategories

Epilepsia

Volumn 44, Issue 5, 2003, Pages 677-687

  De Lanerolle, Nihal C ^a   Kim, Jung H ^a   Williamson, Anne ^a   Spencer, Susan S ^a   Zaveri, Hitten P ^a   Eid, Toye ^a   Spencer, Dennis D ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Electrophysiology; Hippocampal cell counts; Immunohistochemistry; Mesial sclerosis; Paradoxical temporal lobe epilepsy

Indexed keywords

DYNORPHIN; NEUROPEPTIDE Y; SOMATOSTATIN; SUBSTANCE P;

ADULT; ARTICLE; AUTOPSY; CELL DENSITY; CONTROLLED STUDY; DENTATE GYRUS; ELECTROPHYSIOLOGY; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCLEROSIS; TEMPORAL LOBE EPILEPSY; TREATMENT OUTCOME;

ADULT; APOPTOSIS; CELL COUNT; CULTURE TECHNIQUES; DENTATE GYRUS; DYNORPHINS; ELECTROENCEPHALOGRAPHY; EPILEPSY, TEMPORAL LOBE; EVOKED POTENTIALS; FEMALE; FOLLOW-UP STUDIES; HIPPOCAMPUS; HUMANS; IMMUNOENZYME TECHNIQUES; INTERNEURONS; MALE; NEURONS; NEUROPEPTIDE Y; REFERENCE VALUES; RETROSPECTIVE STUDIES; SCLEROSIS; SOMATOSTATIN; SUBSTANCE P; TREATMENT OUTCOME;

EID: 0038666143     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1528-1157.2003.32701.x     Document Type: Article

References (39)

1. Gloor, P. Mesial temporal sclerosis: historical background and an overview from a modern perspective. In: Luders H, ed. Epilepsy surgery. New York: Raven Press, 1991:689-703.
2. Bouchet C. De l'épilepsie considérée dans ses rapports avec l'aliénation mentale: recherche sur la nature et le siége de ces deux maladies. Arch Gén Méd 1825;9:510-42.
3. Sommer W. Erkrankung des Ammonshorns als aetiologisches Moment der Epilepsie. Arch Psychiatr Nervenkr 1880;10:631-75.
4. Lorente de Nó R. Studies on the structure of the cerebral cortex, II: continuation of the study of the ammonic system. J Psychol Neurol (Leipzig) 1934;46:113-77.
5. Bratz E. Ammonshornbefunde bei Epileptikern. Arch Psychiatr Nervenkr 1899;32:820-35.
6. Meencke HJ, Veith G. Hippocampal sclerosis in epilepsy. In: Luders HO, ed. Epilepsy surgery. New York: Raven Press, 1991:705-15.
7. Mouritzen Dam A. Epilepsy and neuron loss in the hippocampus. Epilepsia 1980;21:617-29.
8. Babb TL, Brown WJ, Pretorius J, et al. Temporal lobe volumetric cell densities in temporal lobe epilepsy. Epilepsia 1984;25:729-40.
9. Sagar HJ, Oxbury JM. Hippocampal neuronal loss in temporal lobe epilepsy: correlation with early childhood convulsions. Ann Neurol 1987;22:334-40.
10. Kim JH, Guimaraes PO, Shen M-Y, et al. Hippocampal neuronal density in temporal lobe epilepsy with and without gliomas. Acta Neuropathol 1990;80:41-5.
11. Mathern GW, Kuhlman PA, Mendoza D, et al. Human fascia dentata and hippocampal neuron densities differ depending on the epileptic syndrome and age at first seizure. J Neuropathol Exp Neurol 1997;56:199-212.
12. Bruton CJ. The neuropathology of temporal lobe epilepsy. Oxford: Oxford University Press, 1988.
13. Babb TL. Research on the anatomy and pathology of epileptic tissue. In: Lüders HO, eds. Epilepsy surgery. New York: Raven Press, 1991:719-27.
14. Kim JH. Pathology of epilepsy. Exp Mol Pathol 2001;70:345-67.
15. de Lanerolle NC. The pathology of the epilepsies: insights from pathology to mechanisms of causation of temporal lobe epilepsy. In: Pellock JM, Bourgeois WED, eds. Pediatric epilepsy: diagnosis and therapy. New York: Demos, 2001:45-60.
16. de Lanerolle NC, Kim JH, Brines ML. Cellular and molecular alterations in partial epilepsy. Clin Neurosci 1994;2:64-81.
17. 3H]-U69,539 binding in the human epileptogenic hippocampus. Epilepsy Res 1997;28:189-205.
18. Williamson A. Electrophysiology of epileptic human neocortical and hippocampal neurons maintained in vitro. Clin Neurosci 1994;2:47-52.
19. Spencer DD, Spencer SS, Mattson RH, et al. Access to posterior medial temporal lobe structures in the surgical treatment of temporal lobe epilepsy. Neurosurgery, 1984;15:667-71.
20. Spencer DD, Spencer SS. Surgery for epilepsy. Neurol Clin 1985;3:313-30.
21. de Lanerolle NC, Kim JH, Robbins RJ, et al. Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy. Brain Res 1989;495:387-95.
22. Abercrombie M. Estimation of nuclear population from microtome sections. Anat Rec 1946;94:239-47.
23. Gundersen HJ. The new stereological tools. APMIS 1988;96:379-94;857-81.
24. Sternberger LA. Immunocytochemistry. New York: John Wiley & Sons, 1986.
25. Hsu S, Raine L, Fanger H. The use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981;29:577-80.
26. Williamson A, Spencer SS, Spencer DD. Depth electrode studies and intracellular dentate granule cell recordings in temporal lobe epilepsy. Ann Neurol 1995;38:778-87.
27. Siegel S. Nonparametric statistics for the behavioral sciences. New York: McGraw-Hill, 1956.
28. Mathem GW, Babb TL, Armstrong DL. Hippocampal sclerosis. In: Engel J, Pedley TA, eds. Epilepsy: a comprehensive textbook. Philadelphia: Lippincott-Raven, 1997:135-55.
29. Kim JH. Pathology of seizure disorders. Neuroimag Clin North Am 1995;5:527-45.
30. Engel JJ. Outcome with respect to epileptic seizures. In: Engel J Jr., ed. Surgical treatment of epilepsy. New York: Raven Press, 1987:553-72.
31. Kim RB, Williamson A, Kim JH, et al. Paradoxical temporal lobe epilepsy: clinical, radiographic, pathologic, immunohistochemical and electrophysiologic features. Epilepsia 1998;39(suppl 6):69.
32. Zaveri HP, Duckrow RB, de Lanerolle NC, et al. Distinguishing subtypes of temporal lobe epilepsy with background hippocampal activity. Epilepsia 2001;42:725-30.
33. Sloviter RS. Decreased hippocampal inhibition and a selective loss of interneurons in experimental epilepsy. Science 1987;235:73-6.
34. Patrylo PR, Van den Pol AN, Spencer DD, et al. NPY inhibits glutamatergic excitation in the epileptic human dentate gyrus. J Neurophysiol 1999;82:478-83.
35. O'Connor ER, Sontheimer H, Spencer DD, et al. Astrocytes from human hippocampal epileptogenic foci exhibit action potential-like responses. Epilepsia 1998;39:347-54.
36. Herkenham M. The connections of the nucleus reuniens thalami: evidence for a direct thalamohippocampal pathway in the rat. J Comp Neurol 1978;177:589-610.
37. Yanagihara M, Niimi K, Ono K. Thalamic projections to the hippocampal and entorhinal areas in the cat. J Comp Neurol 1987;266:122-41.
38. Spencer DD, Spencer SS, Mattson RH, et al. Intracerebral masses in patients with intractable partial epilepsy. Neurology 1984;34:432-6.
39. Wolf HK, Roos D, Blümcke I, et al. Perilesional neurochemical changes in focal epilepsies. Acta Neuropathol 1996;91:376-84.