Rift valley fever virus vaccine lacking the NSs and NSm genes is safe, nonteratogenic, and confers protection from viremia, pyrexia, and abortion following challenge in adult and pregnant sheep

Journal of Virology

Volumn 85, Issue 24, 2011, Pages 12901-12909

  Bird, Brian H ^a   Maartens, Louis H ^c   Campbell, Shelley ^a   Erasmus, Baltus J ^c   Erickson, Bobbie R ^a   Dodd, Kimberly A ^a,d   Spiropoulou, Christina F ^a   Cannon, Deborah ^a   Drew, Clifton P ^a   Knust, Barbara ^a   Mcelroy, Anita K ^a,e   Khristova, Marina L ^b   Albariño, César G ^a   Nichol, Stuart T ^a  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c Deltamune (Pty) Ltd   (South Africa)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; RECOMBINANT VACCINE; VIRUS VACCINE;

ABORTION; ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG SENSITIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FEVER; GENE AMPLIFICATION; GENE SEQUENCE; GESTATIONAL AGE; IMMUNOGENICITY; NONHUMAN; PRIORITY JOURNAL; RIFT VALLEY FEVER BUNYAVIRUS; SEROCONVERSION; SHEEP; TERATOGENESIS; TITRIMETRY; VACCINATION; VIREMIA; VIRUS VIRULENCE;

ANIMALS; CONGENITAL ABNORMALITIES; FEMALE; FEVER; GENE DELETION; HUMANS; INJECTIONS, SUBCUTANEOUS; PREGNANCY; RIFT VALLEY FEVER; RIFT VALLEY FEVER VIRUS; SHEEP; SHEEP DISEASES; VACCINES, ATTENUATED; VACCINES, SYNTHETIC; VIRAL NONSTRUCTURAL PROTEINS; VIRAL VACCINES; VIREMIA;

ANIMALIA; OVIS ARIES; RIFT VALLEY FEVER VIRUS;

EID: 84855836879     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06046-11     Document Type: Article

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