Adrenergic regulation of HCN4 channel requires protein association with β2-adrenergic receptor

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23690-23697

  Greene, Derek ^a   Kang, Seungwoo ^a   Kosenko, Anastasia ^a   Hoshi, Naoto ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; CALCIUM CURRENT; CARDIAC FUNCTIONS; COLOCALIZE; CONTRACTION RATE; ION CHANNEL; N-TERMINALS; PROTEIN ASSOCIATIONS; PROTEIN COMPLEXES; RECEPTOR BINDING; SIGNALING MECHANISMS; SYNTHETIC PEPTIDE;

IONS; PEPTIDES;

ENZYME INHIBITION;

BETA 2 ADRENERGIC RECEPTOR; CARRIER PROTEIN; PROTEIN HCN4; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ADRENERGIC ACTIVITY; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; HEART CONTRACTION; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PACEMAKER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM; SINUS NODE;

ADRENERGIC BETA-AGONISTS; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; HEK293 CELLS; HELA CELLS; HUMANS; IMMUNOBLOTTING; ION CHANNEL GATING; ISOPROTERENOL; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MUSCLE PROTEINS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PEPTIDES; PROTEIN BINDING; PROTEIN ISOFORMS; PYRIMIDINES; RATS; RECEPTORS, ADRENERGIC, BETA-2; SEQUENCE HOMOLOGY, AMINO ACID; SINOATRIAL NODE;

EID: 84863633017     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.366955     Document Type: Article

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