Leishmania donovani exploits host deubiquitinating enzyme A20, a negative regulator of TLR signaling, to subvert host immune response

Journal of Immunology

Volumn 189, Issue 2, 2012, Pages 924-934

  Srivastav, Supriya ^a   Kar, Susanta ^a,c   Chande, Ajit G ^b   Mukhopadhyaya, Robin ^b   Das, Pijush K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b TATA MEMORIAL HOSPITAL   (India)

^c CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; ENZYME A20; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DEFENSE MECHANISM; DEUBIQUITINATION; FEEDBACK SYSTEM; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VIVO STUDY; LEISHMANIA DONOVANI; LEISHMANIASIS; MACROPHAGE; MODULATION; MOUSE; NONHUMAN; PARASITE CLEARANCE; PARASITE SURVIVAL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CYSTEINE ENDOPEPTIDASES; DOWN-REGULATION; FEMALE; GLYCOSPHINGOLIPIDS; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEISHMANIA DONOVANI; MACROPHAGES; MAP KINASE KINASE KINASES; MICE; MICE, INBRED BALB C; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 2;

EID: 84863622638     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102845     Document Type: Article

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