Leishmania donovani infection down-regulates TLR2-stimulated IL-12p40 and activates IL-10 in cells of macrophage/monocytic lineage by modulating MAPK pathways through a contact-dependent mechanism

Clinical and Experimental Immunology

Volumn 154, Issue 2, 2008, Pages 224-234

  Chandra, Dinesh ^a   Naik, Sita ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Host pathogens interactions; Immune evasion; Innate immunity; Toll like receptor

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12P40; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LEISHMANIA DONOVANI; LEISHMANIASIS; MACROPHAGE; MOLECULAR MECHANICS; MONOCYTE; PARASITE VIABILITY; PRIORITY JOURNAL;

ANIMALS; ANISOMYCIN; BUTADIENES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-12 SUBUNIT P40; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MAP KINASE SIGNALING SYSTEM; MONOCYTES; NITRILES; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 53349153579     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03741.x     Document Type: Article

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