Uncoupling protein 2 negatively regulates mitochondrial reactive oxygen species generation and induces phosphatase-mediated anti-inflammatory response in experimental visceral leishmaniasis

Journal of Immunology

Volumn 187, Issue 3, 2011, Pages 1322-1332

  Ball, Writoban Basu ^a   Kar, Susanta ^a   Mukherjee, Madhuchhanda ^a   Chande, Ajit G ^b   Mukhopadhyaya, Robin ^b   Das, Pijush K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b TATA MEMORIAL HOSPITAL   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; INTERLEUKIN 10; INTERLEUKIN 12; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE SHP 1; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; LEISHMANIA DONOVANI; MACROPHAGE; MITOCHONDRION; MOUSE; NONHUMAN; PARASITE CLEARANCE; PARASITE SURVIVAL; PRIORITY JOURNAL; UPREGULATION; VISCERAL LEISHMANIASIS;

ANIMALS; CELL LINE; DOWN-REGULATION; ENZYME ACTIVATION; HOST-PATHOGEN INTERACTIONS; INFLAMMATION MEDIATORS; ION CHANNELS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MACROPHAGES; MICE; MICE, INBRED BALB C; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTEIN TYROSINE PHOSPHATASES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

EID: 80051637812     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1004237     Document Type: Article

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