A variant of the breast cancer type 2 susceptibility protein (BRC) repeat is essential for the RECQL5 helicase to interact with RAD51 recombinase for genome stabilization

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23808-23818

  Islam, M Nurul ^a,b   Paquet, Nicolas ^b   Fox III, David ^a   Dray, Eloise ^b   Zheng, Xiao Feng ^b   Klein, Hannah ^c   Sung, Patrick ^b   Wang, Weidong ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; HELICASES; HOMOLOGOUS RECOMBINATION; IN-VITRO; IN-VIVO; INTERACTION MODULES; POINT MUTATIONS; RECOMBINASE ACTIVITY; REGULATORY PROTEIN; SISTER CHROMATID EXCHANGE; STRUCTURAL MOTIFS; SUSCEPTIBILITY PROTEINS; TUMOR SUPPRESSORS;

BODY FLUIDS; DISEASES;

PROTEINS;

BRCA2 PROTEIN; CAMPTOTHECIN; HELICASE; RAD51 PROTEIN; REGULATOR PROTEIN;

ARTICLE; BREAST CANCER; GENE MUTATION; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; IMMUNOPRECIPITATION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PURIFICATION; SISTER CHROMATID EXCHANGE; TUMOR SUPPRESSOR GENE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLOTTING, WESTERN; BRCA2 PROTEIN; CAMPTOTHECIN; CELL LINE, TUMOR; DNA REPLICATION; GENOMIC INSTABILITY; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; RECQ HELICASES; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84863614596     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.375014     Document Type: Article

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