Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells

Journal of Immunology

Volumn 189, Issue 2, 2012, Pages 1036-1042

  Ramon, Sesquile ^a   Gao, Fei ^b   Serhan, Charles N ^b   Phipps, Richard P ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 HYDROXYDOSAHEXAENOIC ACID; MEMBRANE PROTEIN; POLYUNSATURATED FATTY ACID; PROTECTIN D1; RESOLVIN D1; SPECIALIZED PRORESOLVING MEDIATOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIBODY SECRETING CELL; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOPRECIPITATION; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; REAL TIME POLYMERASE CHAIN REACTION; SECRETORY CELL; SPLEEN;

ANIMALS; ANTIBODY-PRODUCING CELLS; B-LYMPHOCYTE SUBSETS; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; DOCOSAHEXAENOIC ACIDS; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; METABOLOMICS; MICE; MICE, INBRED STRAINS; TANDEM MASS SPECTROMETRY; UP-REGULATION;

EID: 84863611031     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103483     Document Type: Article

References (35)

1. Simopoulos, A. P. 2002. Omega-3 fatty acids in inflammation and autoimmune diseases. J. Am. Coll. Nutr. 21: 495-505. (Pubitemid 36026261)
2. Serhan, C. N. 2007. Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Annu. Rev. Immunol. 25: 101-137. (Pubitemid 46697904)
3. Petasis, N. A., I. Akritopoulou-Zanze, V. V. Fokin, G. Bernasconi, R. Keledjian, R. Yang, J. Uddin, K. C. Nagulapalli, and C. N. Serhan. 2005. Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins. Prostaglandins Leukot. Essent. Fatty Acids 73: 301-321. (Pubitemid 41253490)
4. Serhan, C. N., N. Chiang, and T. E. Van Dyke. 2008. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8: 349-361. (Pubitemid 351595216)
5. Oh, S. F., T. W. Vickery, and C. N. Serhan. 2011. Chiral lipidomics of E-series resolvins: aspirin and the biosynthesis of novel mediators. Biochim. Biophys. Acta 1811: 737-747.
6. Ariel, A., N. Chiang, M. Arita, N. A. Petasis, and C. N. Serhan. 2003. Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells. J. Immunol. 170: 6266-6272. (Pubitemid 36682612)
7. Godson, C., S. Mitchell, K. Harvey, N. A. Petasis, N. Hogg, and H. R. Brady. 2000. Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. J. Immunol. 164: 1663-1667. (Pubitemid 30108713)
8. Lee, T. H., C. E. Horton, U. Kyan-Aung, D. Haskard, A. E. Crea, and B. W. Spur. 1989. Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-L-methionyl-L-leucyl-L- phenylalanine. Clin. Sci. 77: 195-203. (Pubitemid 19203563)
9. Zhang, L., X. Zhang, P. Wu, H. Li, S. Jin, X. Zhou, Y. Li, D. Ye, B. Chen, and J. Wan. 2008. BML-111, a lipoxin receptor agonist, modulates the immune response and reduces the severity of collagen-induced arthritis. Inflamm. Res. 57: 157-162. (Pubitemid 351601325)
10. Poulsen, R. C., K. H. Gotlinger, C. N. Serhan, and M. C. Kruger. 2008. Identification of inflammatory and proresolving lipid mediators in bone marrow and their lipidomic profiles with ovariectomy and omega-3 intake. Am. J. Hematol. 83: 437-445. (Pubitemid 351742789)
11. Schneider, C., D. S. Keeney, W. E. Boeglin, and A. R. Brash. 2001. Detection and cellular localization of 12R-lipoxygenase in human tonsils. Arch. Biochem. Biophys. 386: 268-274. (Pubitemid 32989317)
12. Bafica, A., C. A. Scanga, C. Serhan, F. Machado, S. White, A. Sher, and J. Aliberti. 2005. Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. J. Clin. Invest. 115: 1601-1606. (Pubitemid 40814668)
13. Hong, S., T. F. Porter, Y. Lu, S. F. Oh, P. S. Pillai, and C. N. Serhan. 2008. Resolvin E1 metabolome in local inactivation during inflammation- resolution. J. Immunol. 180: 3512-3519.
14. Yang, R., N. Chiang, S. F. Oh, and C. N. Serhan. 2011. Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes. Curr. Protoc. Immunol. Chapter 14: Unit 14.26.
15. Bernard, M. P., and R. P. Phipps. 2007. CpG oligodeoxynucleotides induce cyclooxygenase-2 in human B lymphocytes: implications for adjuvant activity and antibody production. Clin. Immunol. 125: 138-148. (Pubitemid 47562898)
16. Ryan, E. P., S. J. Pollock, T. I. Murant, S. H. Bernstein, R. E. Felgar, and R. P. Phipps. 2005. Activated human B lymphocytes express cyclooxygenase-2 and cyclooxygenase inhibitors attenuate antibody production. J. Immunol. 174: 2619-2626. (Pubitemid 40279675)
17. Serhan, C. N., K. Gotlinger, S. Hong, Y. Lu, J. Siegelman, T. Baer, R. Yang, S. P. Colgan, and N. A. Petasis. 2006. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. J. Immunol. 176: 1848-1859. (Pubitemid 43134330)
18. Harris, S. G., J. Padilla, L. Koumas, D. Ray, and R. P. Phipps. 2002. Prosta-glandins as modulators of immunity. Trends Immunol. 23: 144-150.
19. Mongini, P. K., J. K. Inman, H. Han, R. J. Fattah, S. B. Abramson, and M. Attur. 2006. APRIL and BAFF promote increased viability of replicating human B2 cells via mechanism involving cyclooxygenase 2. J. Immunol. 176: 6736-6751. (Pubitemid 43787856)
20. Arita, M., M. Yoshida, S. Hong, E. Tjonahen, J. N. Glickman, N. A. Petasis, R. S. Blumberg, and C. N. Serhan. 2005. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis. Proc. Natl. Acad. Sci. USA 102: 7671-7676. (Pubitemid 40741029)
21. Maddox, J. F., and C. N. Serhan. 1996. Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction. J. Exp. Med. 183: 137-146.
22. Hachicha, M., M. Pouliot, N. A. Petasis, and C. N. Serhan. 1999. Lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor 1alpha-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis. J. Exp. Med. 189: 1923-1930.
23. Ariel, A., G. Fredman, Y. P. Sun, A. Kantarci, T. E. Van Dyke, A. D. Luster, and C. N. Serhan. 2006. Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression. Nat. Immunol. 7: 1209-1216. (Pubitemid 44594317)
24. Ariel, A., P. L. Li, W. Wang, W. X. Tang, G. Fredman, S. Hong, K. H. Gotlinger, and C. N. Serhan. 2005. The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering. J. Biol. Chem. 280: 43079-43086. (Pubitemid 43049274)
25. Aliberti, J., C. Serhan, and A. Sher. 2002. Parasite-induced lipoxin A4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection. J. Exp. Med. 196: 1253-1262. (Pubitemid 35304190)
26. Arita, M., F. Bianchini, J. Aliberti, A. Sher, N. Chiang, S. Hong, R. Yang, N. A. Petasis, and C. N. Serhan. 2005. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J. Exp. Med. 201: 713-722. (Pubitemid 40395117)
27. Arce, S., E. Luger, G. Muehlinghaus, G. Cassese, A. Hauser, A. Horst, K. Lehnert, M. Odendahl, D. Hönemann, K. D. Heller, et al. 2004. CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations. J. Leukoc. Biol. 75: 1022-1028. (Pubitemid 38720643)
28. Avery, D. T., J. I. Ellyard, F. Mackay, L. M. Corcoran, P. D. Hodgkin, and S. G. Tangye. 2005. Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage. J. Immunol. 174: 4034-4042. (Pubitemid 40395979)
29. Bernard, M. P., and R. P. Phipp. 2010. Inhibition of cyclooxygenase-2 impairs the expression of essential plasma cell transcription factors and human Blymphocyte differentiation. Immunology 129: 87-96.
30. Shapiro-Shelef, M., and K. Calame. 2005. Regulation of plasma-cell development. Nat. Rev. Immunol. 5: 230-242. (Pubitemid 40364824)
31. Reimold, A. M., N. N. Iwakoshi, J. Manis, P. Vallabhajosyula, E. Szomolanyi-Tsuda, E. M. Gravallese, D. Friend, M. J. Grusby, F. Alt, and L. H. Glimcher. 2001. Plasma cell differentiation requires the transcription factor XBP-1. Nature 412: 300-307. (Pubitemid 32691837)
32. Nutt, S. L., D. Eberhard, M. Horcher, A. G. Rolink, and M. Busslinger. 2001. Pax5 determines the identity of B cells from the beginning to the end of Blymphopoiesis. Int. Rev. Immunol. 20: 65-82. (Pubitemid 32500866)
33. Lin, K. I., C. Angelin-Duclos, T. C. Kuo, and K. Calame. 2002. Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells. Mol. Cell. Biol. 22: 4771-4780. (Pubitemid 34620412)
34. Honjo, T., H. Nagaoka, R. Shinkura, and M. Muramatsu. 2005. AID to overcome the limitations of genomic information. Nat. Immunol. 6: 655-661. (Pubitemid 41716738)
35. Tarte, K., J. De Vos, T. Thykjaer, F. Zhan, G. Fiol, V. Costes, T. Rème, E. Legouffe, J. F. Rossi, J. Shaughnessy, Jr., et al. 2002. Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts. Blood 100: 1113-1122. (Pubitemid 34864260)