Inhibition of cyclooxygenase-2 impairs the expression of essential plasma cell transcription factors and human B-lymphocyte differentiation

Immunology

Volumn 129, Issue 1, 2010, Pages 87-96

  Bernard, Matthew P ^a   Phipps, Richard P ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Antibody responses; B cells; CpG DNA; Transcription factors; Vaccines

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; B LYMPHOCYTE ANTIBODY; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CD38 ANTIGEN; CYCLOOXYGENASE 2; IGG2 ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G3 ANTIBODY; IMMUNOGLOBULIN G4 ANTIBODY; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; SYNDECAN 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY PRODUCING CELL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODY FORMATION; ANTIGENS, CD38; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLOOXYGENASE INHIBITORS; HUMANS; IMMUNOGLOBULIN ISOTYPES; INFECTION CONTROL; NITROBENZENES; PYRAZOLES; REPRESSOR PROTEINS; SULFONAMIDES; VACCINES;

EID: 71649111414     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03152.x     Document Type: Article

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