Resistance of colon cancer to 5-fluorouracil may be overcome by combination with chloroquine, an in vivo study

Anti-Cancer Drugs

Volumn 23, Issue 7, 2012, Pages 675-682

  Sasaki, Kazuhito ^a   Tsuno, Nelson H ^a   Sunami, Eiji ^a   Kawai, Kazushige ^a   Hongo, Kumiko ^a   Hiyoshi, Masaya ^a   Kaneko, Manabu ^a   Murono, Koji ^a   Tada, Noriko ^a   Nirei, Takako ^a   Takahashi, Koki ^a   Kitayama, Joji ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

5 fluorouracil; autophagy; chloroquine; colorectal cancer

Indexed keywords

CHLOROQUINE; FLUOROURACIL; PROTEIN BAD; PROTEIN BAX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; BODY WEIGHT; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CANCER THERAPY; COLON CANCER; COLORECTAL CANCER; CONTROLLED STUDY; DRUG INHIBITION; EXPERIMENTAL ANIMAL; IMMUNOBLOTTING; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHLOROQUINE; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; DRUG RESISTANCE, NEOPLASM; FEMALE; FLUOROURACIL; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; RNA NUCLEOTIDYLTRANSFERASES; TRANSCRIPTION FACTORS; TUMOR BURDEN;

EID: 84863592632     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e328353f8c7     Document Type: Article

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