Ki-ras oncogene mutations in head and neck carcinomas;HAUFIGKEIT VON PUNKTMUTATIONEN IN KI-RAS CODON 12 UND 13 BEI PLATTENEPITHELKARZINOMEN DER KOPF-HALS-REGION

Laryngo- Rhino- Otologie

Volumn 75, Issue 8, 1996, Pages 465-470

  Rathcke, I O ^a   Gottschlich, S ^a   Gorogh T ^a   Lippert, B M ^a   Werner, J A ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Ki ras gene; Point mutation; Polymerase chain reaction; Single strand conformation polymorphism analysis; Squamous cell carcinoma; Upper aerodigestive tract

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; HEAD AND NECK CARCINOMA; HUMAN; HUMAN TISSUE; MALE; ONCOGENE; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; BIOPSY; CANCER STAGING; CODON; GENETICS; HYPOPHARYNX; HYPOPHARYNX TUMOR; LARYNX; LARYNX TUMOR; MIDDLE AGED; PATHOLOGY; PROGNOSIS; SQUAMOUS CELL CARCINOMA;

HRAS PROTEIN, HUMAN; PROTEIN P21;

AGED; BIOPSY; CARCINOMA, SQUAMOUS CELL; CODON; FEMALE; HUMANS; HYPOPHARYNGEAL NEOPLASMS; HYPOPHARYNX; LARYNGEAL NEOPLASMS; LARYNX; MALE; MIDDLE AGED; NEOPLASM STAGING; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROGNOSIS; PROTO-ONCOGENE PROTEINS P21(RAS);

EID: 0029838631     PISSN: 09358943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-997616     Document Type: Article

References (54)

1. Anderson, J. A., J. C. Irish, C. M. McLachlin, B. Y. Ngan: Ha-ras oncogene mutation and human papillomavirus infection in oral carcinomas. Arch. Otolaryngol. Head Neck Surg. 120 (1994) 755-760
2. Anderson, J. A., J. C. Irish, B. C. Ngan: Prevalence of ras oncogene mutation in head and neck carcinomas. J. Otolaryngol. 21 (1992) 321-326
3. Anwar, K., K. Nakakuki, H. Naiki, M. Inuzuka: Ras gene mutations and human papillomavirus infection are common in human laryngeal carcinoma. Int. J. Cancer 53 (1993) 22-28
4. Barbacid, M.: Ras genes. Ann. Rev. Biochem. 56 (1987) 779-827
5. Beaucage, S. L., M. H. Carnthers: Deoxynucleoside phosphoramidites: a new class of key intermediates for deoxypolynucleotide synthesis. Tetrahedron Lett. 22 (1981) 1859-1862
6. Benhattar, J., L. Losi, P. Chaubert, J. C. Givel, J. Costa: prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology 104 (1993) 1044-1048
7. Bos, J. L.: Ras oncogenes in human cancer: a review. Cancer Res. 49 (1989) 4682-4689
8. Bos, J. L., D. Toksoz, c. J. Marshall, M. Verlaan-de Vries, G. H. Veeneman, A. J. van der Eb, J. H. van Boom, J. W. Janssen, A. C. Steenvoorden: Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukemia. Nature 315 (1985) 726-730
9. Chang, S. E., P. Bhatia, N. W. Johnson, P. R. Morgan, F. McCormick, B. Young, L. Hiorns: Ras mutations in United Kingdom examples of oral malignancies are infrequent. Int. J. Cancer 48 (1991) 409-412
10. Daus, H., L. Trumper, B. Burger, G. Jacobs, S. Kriener, G. von Blohn, M. Zeitz, M. Pfreundschuh: Ki-ras-Mutation als molekularer Tumormarker für Pankreaskarzinome. Dtsch. Med. Wochenschr. 120 (1995) 821-825
11. Ellis, R. W., D. DeFeo, T. Y. Shih, M. A. Gonda, H. A. Young, N. Tsuchida, D. R. Low, E. M. Scolnick: The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature 292 (1981) 506-511
12. Field, J. K.: Oncogenes and tumor-suppressor genes in squamous cell carcinoma of the head and neck. Eur. J. Cancer B. Oral. Oncol. 28 (1992) 67-76
13. Field, J. K., D. A. Spandidos: The role of ras and myc oncogenes in human solid tumors and their relevance in diagnosis and prognosis. Anticancer Res. 10 (1990) 1-22
14. Guerrero, I., A. Pellicer: Mutational activation of oncogenes in animal model systems of carcinogenesis. Mutat. Res. 185 (1987) 293-308
15. Harvey, J. J.: An unidentified virus which causes the rapid production of tumors in mice. Nature 204 (1964) 1104-1105
16. Hayashi, K.: PCR-SSCP: a simple and sensitive method for detection of mutations in the genomic DNA. PCR Methods Appl. 1 (1991) 34-38
17. Hirano, T., P. E. Steele, J. L. Gluckman: Low incidence of point mutation at codon 12 of Ki-ras proto-oncogene in squamous cell carcinoma of the upper aerodigestive tract. Ann. Otol. Rhinol. Laryngol. 100 (1992) 597-599
18. Hollstein, M. C., A. M. Smits, C. Galiana, H. Yamasaki, J. L. Bos, A. Mandard, C. Partensky, O. Montesano: Amplification on EGF receptor gene but no evidence of ras mutations in primary human esophageal cancers. Cancer Res. 48 (1988) 5119-5123
19. Howell, R. E., F. S. H. Wong, R. G. Fenwick: A transforming Kirsten ras oncogene in an oral squamous carcinoma. J. Oral. Pathol. Med. 19 (1990) 301-305
20. Hruban, R. H., A. D. van Mansfeld, G. J. Offerhaus, D. H. van Weerin, D. C. Allison, S. N. Goodman, T. W. Kensler, K. K. Bose, J. L. Cameron, J. L. Bos: K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization. Am J. Pathol. 143 (1993) 545-554
21. Huebner, R. J., G. J. Todaro: Oncogenes of RNA tumor viruses as determinants of cancer. Proc. Acad. Natl. Sci. USA 64 (1969) 1087-1094
22. Irish, J. C.: Oncogenes in head and neck cancer: erb-B and ras oncogene activation in laryngeal carcinoma. Laryngeal Cancer. In Smee, R., G. P. Bridger (Hrsg.): Proceedings of the 2nd World Congress on Laryngeal Cancers. Bd. 1063. Elsevier, Amsterdam (1994) 172-177
23. Irish, J. C., A. Bernstein: Oncogenes in head and neck cancer. Laryngoscope 103 (1993) 42-52
24. Jafari, M., T. Papp, S. Kirchner, U. Diener, D. Henschler, G. Burg, D. Schiffmann: Analysis of ras mutations in human melanocytic lesions: activation of the ras gene seems to be associated with the nodular type of human malignant melanoma. J. Cancer Res. Clin. Oncol. 121 (1995) 23-30
25. Kalthoff, H., W. Schmiegel, C. Roeder, D. Kasche, A. Schmidt, G. Lauer, H.-G. Thiele, G. Honold, K. Pantel, G. Riethmüller, E. Scherer, J. Maurer, H. Maacke, W. Deppert: p53 and Ki-ras alterations in pancreatic epithelial cell lesions. Oncogene 8 (1993) 289-298
26. Kiaris, H., D. A. Spandidos, A. S. Jones, E. D. Vaughan, J. K. Field: Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck. Br. J. Cancer 72 (1995) 123-128
27. Knowles, M. A., M. Williamson: Mutation of H-ras is infrequent in bladder cancer: confirmation by single-strand conformation polymorphism analysis, designed restriction fragment length polymorphisms, and direct sequencing. Cancer Res. 53 (1993) 133-139
28. Korn, S. H., P. T. Moerkerk, A. F. de Goejj: K-ras point mutations in routinely processed tissues: non-radioactive screening by single strand conformational polymorphism analysis. J. Clin. Pathol. 46 (1993) 621-623
29. Kuo, M. Y., J. H. Jeng, C. P. Chiang, L. L. Hahn: Mutations of Ki-ras oncogene codon 12 in betel quid chewing-related human oral squamous cell carcinoma in Taiwan. J. Oral Pathol. Med. 23 (1994) 70-74
30. Lemoine, N. R., E. S. Mayall, F. S. Wyllie, C. J. Farr, D. Huthes, R. A. Padua, V. Thurston, E. D. Williams, D. Wynford-Thomas: Activated ras oncogenes in human thyroid cancers. Cancer Res. 48 (1988) 4459-4463
31. Lemoine, N. R., S. Jain, C. M. Hughes, S. L. Staddon, B. Maillet, P. A. Hall, G. Klöppel: Ki-ras oncogene activation in preinvasive pancreatic cancer. Gastroenterology 102 (1992) 230-236
32. Levesque, P., N. Ramchurren, K. Saini, A. Joyce, J. Liberino, I. C. Summerhayes: Screening of human bladder tumors and urine sediments for the presence of H-ras mutations. Int. J. Cancer 55 (1993) 785-790
33. Li, S., R. Rosell, A. Urban. A. Font, A. Ariza, P. Armengol, A. Abad, J. J. Navas, M. Monto: K-ras gene point mutation: a stable tumor marker in non-small cell lung carcinoma. Lung Cancer 11 (1994) 19-27
34. McGrath, J. P., D. J. Capon, D. H. Smith, E. Y. Chen, P. H. Seeburg, D. V. Goeddel, A. D. Levinson: Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene. Nature 304 (1983) 501-506
35. Minamoto, T., N. Yamashita, A. Ochiai, M. Mai, T. Sugimura, Z. Ronai, H. Esumi: Mutant K-ras in apparently normal mucosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis. Cancer 75 (1995) 1520-1526
36. Okutsu, S., A. Takeda, T. Suzuki, Y. Nakajima, J. Sato, K. Suda, M. Fukuda, t. Usami, T. Himiya, K. Kusama, I. Kudo, I. Moro: Expression of ras-P21 and ras gene alteration in pleomorphic adenomas. J. Nihon Univ. Sch. Dent.35 (1993) 200-203
37. Orita, M., H. Iwahana, H. Kanazawa, K. Hayashi, T. Sekiya: Detection polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc. Natl. Acad. Sci. USA 86 (1989) 2766-2770
38. Reddy, E. P., R. K. Reynolds, E. Santos, M. Barbacid: A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature 300 (1982) 149-152
39. Rodenhuis, S., R. J. Slebos: The ras oncogenes in human lung cancer. Am. Rev. Respir. Dis. 142 (1990) 27-30
40. Rumsby, G., R. L. Carter, B. A. Gusterson: Low incidence of ras oncogene activation in human squamous cell carcinomas. Br. J. Cancer 61 (1990) 365-368
41. Saiki, R. K., S. Scharf, F. Faloona, K. B. Mullis, G. T. Horn, H. A. Erlich, N. Arnheim: Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230 (1985) 1350-1354
42. Sanger, F., S. Nicklen, A. R. Coulson: DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74 (1977) 5463-5467
43. Saranath, D., S. E. Chang, L. T. Bhoite, R. G. Panchal, I. B. Kerr, A. R. Mehta, N. W. Johnson, M. G. Deo: High frequency mutation in codons 12 and 61 of Ha-ras oncogene in chewing tobacco-related human oral carcinoma in India. Br. J. Cancer 63 (1991) 573-578
44. Shimizu, K., D. Birnbaum, M. A. Ruley, O. Fasano, Y. Suard, L. Edlund, E. Taparowsky, M. Goldfarb, M. Wigler: The structure of the Ki-ras gene of the human lung carcinom cell line Calu-1. Nature 304 (1983) 497-500
45. Soto, D., S. Sukumar: Improved detection of mutations in the p53 gene in human tumors as single-stranded conformation polymorphs and double-stranded heteroduplex DNA. PCR Methods Appl. 2 (1992) 96-98
46. Sugano, K., A. Kyogoku, N. Fukayama, H. Ohkura, Y. Shimosato, T. Sekiya, K. Hayashi: Methods in laboratory investigation. Rapid and simple detection of Ki-ras-2 gene codon 12 mutations by nonradioisotopic single-strand conformation polymorphism analysis. Lab. Invest. 68 (1993) 361-366
47. Suzuki, Y., M. Orita, M. Shiraishi, K. Hayashi, T. Sekiya: Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene 5 (1990) 1037-1043
48. Takahashi-Fujii, A., Y. Ishino, A. Shimada, I. Kato: Practical application of fluorescencebased image analyzer for PCR single-stranded conformation polymorphism analysis used in detection of multiple point mutations. PCR Methods Appl. 2 (1993) 323-327
49. Victor, T., R. Du Toit, A. M. Jordaan, A. J. Bester, P. D. van Helden: No evidence for point mutations in codons 12, 13, and 61 of the ras gene in a high-incidence area for esophageal and gastric cancer. Cancer Res. 50 (1990) 4911-4914
50. Wagner, S. N., H. M. Ockenfels, C. Wagner, H. Hofler, M. Goos: Ras gene mutations: a rare event in nonmetastatic primary malignant melanoma. J. Invest. Dermatol. 104 (1995) 868-871
51. Weinberg, R. A.: Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis. Cancer Res. 49 (1989) 3713-3721
52. Westra, W. H., R. J. Slebos, G. J. Offerhaus, S. N. Goodman, S. G. Evers, T. W. Kensler, F. B. Askin, S. Rodenhuis, R. H. Hruban: Ki-ras oncogene activation in lung adenocarcinomas from former smokers. Cancer 72 (1993) 432-438
53. Yarbrough, W. G., C. Shores, d. L. Witsell, M. C. Weissler, M. E. Fidler, T. M. Gilmer: Ras mutations and expression in head and neck squamous cell carcinomas. Laryngoscope 104 (1994) 1337-1347
54. Yeudall, W. A., L. K. Torrance, K. A. Elsegood, P. Speight, C. Scully, S. S. Prime: Ras gene point mutation is a rare event in premalignant tissues and malignant cells and tissues from oral mucosal lesions. Eur. J. Cancer B. Oral Oncol. 29 B (1993) 63-67