Evolution of CRISPs associated with toxicoferan-reptilian venom and mammalian reproduction

Molecular Biology and Evolution

Volumn 29, Issue 7, 2012, Pages 1807-1822

  Sunagar, Kartik ^a,b   Johnson, Warren E ^c   O'Brien, Stephen J ^c,d   Vasconcelos, Vítor ^a,b   Antunes, Agostinho ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c NATIONAL CANCER INSTITUTE   (United States)

^d ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

Author keywords

adaptive evolution; CRISP; cysteine rich secretory proteins; mammalian immune system; mammalian reproduction; positive selection; toxicoferan reptilian venom evolution

Indexed keywords

CYSTEINE; CYSTEINE RICH SECRETORY PROTEIN; HEMOTOXIN; NEUROTOXIN; SECRETORY PROTEIN; SNAKE VENOM; TOXICOFERAN REPTILIAN VENOM; TOXIN; UNCLASSIFIED DRUG; VENOM; VIPER VENOM;

AMINO ACID SEQUENCE; ARTICLE; COLUBRIDAE; CONTROLLED STUDY; CYSTEINE RICH SECRETORY PROTEIN 1 GENE; CYSTEINE RICH SECRETORY PROTEIN 2 GENE; CYSTEINE RICH SECRETORY PROTEIN 3 GENE; CYSTEINE RICH SECRETORY PROTEIN GENE; ELAPIDAE; EVOLUTIONARY HOMOLOGY; EVOLUTIONARY RATE; GENE; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC SELECTION; JAW; LIZARD; MAMMAL; MOLECULAR EVOLUTION; MOLECULAR MODEL; MOLECULAR PHYLOGENY; NONHUMAN; NUCLEOTIDE SEQUENCE; POISONOUS ANIMAL; PREDATION; PREDATOR PREY INTERACTION; PROTEIN DOMAIN; PURIFYING SELECTION; REPRODUCTION; REPTILE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SNAKE; STRUCTURE ANALYSIS; VIPERIDAE;

ANIMALS; EVOLUTION, MOLECULAR; HUMANS; LIZARDS; MEMBRANE GLYCOPROTEINS; MICE; MODELS, MOLECULAR; PHYLOGENY; REPTILIAN PROTEINS; SNAKES; VENOMS;

ANGUIMORPHA; COLUBRIDAE; ELAPIDAE; MAMMALIA; REPTILIA; SERPENTES; SQUAMATA; VERTEBRATA; VIPERIDAE;

EID: 84863583935     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mss058     Document Type: Article

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