Blocking effect and crystal structure of natrin toxin, a cysteine-rich secretory protein from Naja atra venom that targets the BKCa channel

Biochemistry

Volumn 44, Issue 30, 2005, Pages 10145-10152

  Wang, Jing ^a,b   Shen, Bing ^a,b   Guo, Min ^a,b   Lou, Xiaohua ^a,b   Duan, Yuanyuan ^a   Cheng, Xin Ping ^a   Teng, Maikun ^a,b,d   Niu, Liwen ^a,b,d   Liu, Qun ^c   Huang, Qingqiu ^c   Hao, Quan ^c  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c Department of Obstetrics Gynecology   (United States)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CALCIUM COMPOUNDS; CONCENTRATION (PROCESS); CRYSTAL STRUCTURE; POTASSIUM;

CALCIUM-ACTIVATED POTASSIUM; CYSTEINE-RICH DOMAIN (CRD); ION CHANNELS; PROTEIN-PROTEIN INTERACTION;

PROTEINS;

CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CYCLIC NUCLEOTIDE; CYSTEINE; CYSTEINE RICH SECRETORY PROTEIN; NATRIN; SECRETORY PROTEIN; SNAKE VENOM; TOXIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; MALE; MOUSE; NAJA ATRA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SNAKE; STRUCTURE ANALYSIS; THORACIC AORTA;

AMINO ACID SEQUENCE; ANIMALS; AORTA, THORACIC; COBRA VENOMS; CROTALID VENOMS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ION CHANNEL GATING; MALE; MEMBRANE GLYCOPROTEINS; MICE; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; SOLUTIONS;

NAJA ATRA;

EID: 23044468262     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050614m     Document Type: Article

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