Osthole, a herbal compound, alleviates nucleus pulposus-evoked nociceptive responses through the suppression of overexpression of acid-sensing ion channel 3 (ASIC3) in rat dorsal root ganglion

Medical Science Monitor

Volumn 18, Issue 6, 2012, Pages

  He, Qiu Lan ^a   Chen, Yuling ^b   Qin, Jian ^a   Mo, Sui Lin ^a   Wei, Ming ^a   Zhang, Jin Jun ^a   Li, Mei Na ^a   Zou, Xue Nong ^a   Zhou, Shu Feng ^c   Chen, Xiao Wu ^d   Sun, Lai Bao ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Acid sensing ion channel 3 (ASIC3); Hyperalgesia; Lumbar disc herniation (LDH); Membrane potential; Osthole

Indexed keywords

ACID SENSING ION CHANNEL 3; AMILORIDE; CATION CHANNEL; OSTHOLE; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; FLUORESCENCE; HYPERALGESIA; MALE; MEMBRANE POTENTIAL; NOCICEPTION; NONHUMAN; NUCLEUS PULPOSUS; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; UPREGULATION; WESTERN BLOTTING;

EID: 84863548740     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/MSM.882899     Document Type: Article

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