Chronic myelogenous leukemia stem and progenitor cells demonstrate chromosomal instability related to repeated breakage-fusion-bridge cycles mediated by increased nonhomologous end joining

Blood

Volumn 119, Issue 26, 2012, Pages 6187-6197

  Chakraborty, Sujata ^a   Stark, Jeremy M ^a   Sun, Can Lan ^a   Modi, Hardik ^a   Chen, WenYong ^a   O'Connor, Timothy R ^a   Forman, Stephen J ^a   Bhatia, Smita ^a   Bhatia, Ravi ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; HISTONE H2AX;

ARTICLE; CANCER STEM CELL; CELL CYCLE PARAMETERS; CELL DIVISION; CHROMOSOMAL INSTABILITY; CHROMOSOME 1; CHROMOSOME 11; CHROMOSOME 21; CHROMOSOME 3; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUSION; HISTONE PHOSPHORYLATION; HUMAN; HUMAN CELL; IONIZING RADIATION; MICRONUCLEUS; NUCLEOPLASMIC BRIDGE; PRIORITY JOURNAL; RADIATION DOSE;

EID: 84863530603     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-05-352252     Document Type: Article

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