Vas deferens smooth muscle responses to the nitric oxide-independent soluble guanylate cyclase stimulator BAY 41-2272

European Journal of Pharmacology

Volumn 688, Issue 1-3, 2012, Pages 49-55

  Da Silva, Fábio H ^a   Claudino, Mário A ^b   Báu, Fernando R ^a   Rojas Moscoso, Julio A ^a   Mónica, Fabíola Z ^a   De Nucci, Gilberto ^a   Antunes, E ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSIDADE SÃO FRANCISCO   (Brazil)

Author keywords

Adrenoceptor; Cyclic GMP; Ejaculatory functions; Neurogenic contractions

Indexed keywords

4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; CYCLIC GMP; GUANYLATE CYCLASE ACTIVATOR; GUANYLATE CYCLASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CONTROLLED STUDY; DRUG ACTIVITY; ELECTRIC FIELD; ELECTROSTIMULATION; EPIDIDYMIS; IN VITRO STUDY; MALE; NONHUMAN; PREMATURE EJACULATION; PRIORITY JOURNAL; PROSTATE; RAT; REVIEW; SMOOTH MUSCLE RELAXATION; VAS DEFERENS;

EID: 84863529323     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.05.009     Document Type: Article

References (43)

1. I.A. Abdel-Hamid Phosphodiesterase 5 inhibitors in rapid ejaculation: potential use and possible mechanisms of action Drugs 64 2004 13 26
2. R.J. Allcorn, T.C. Cunnane, and K. Kirkpatrick Actions of alpha, beta-methylene ATP and 6-hydroxydopamine on sympathetic neurotransmission in the vas deferens of the guinea-pig, rat and mouse: support for cotransmission Br. J. Pharmacol. 89 1986 647 659
3. K.E. Andersson, and I.A. Abdel-Hamid Therapeutic targets for premature ejaculation Maturitas 70 2011 26 33
4. J.S. Baracat, C.E. Teixeira, C.E. Okuyama, F.B. Priviero, R. Faro, E. Antunes, and G. De Nucci Relaxing effects induced by the soluble guanylyl cyclase stimulator BAY 41-2272 in human and rabbit corpus cavernosum Eur. J. Pharmacol. 477 2003 163 169
5. F.R. Báu, F.Z. Mónica, F.B. Priviero, L. Baldissera Jr., G. De Nucci, and E. Antunes Evaluation of the relaxant effect of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in isolated detrusor smooth muscle Eur. J. Pharmacol. 637 2010 171 177
6. E. Bischoff, M. Schramm, A. Straub, A. Feurer, and J.P. Stasch BAY 41-2272: a stimulator of soluble guanylyl cyclase induces nitric oxide-dependent penile erection in vivo Urology 61 2003 464 467
7. A.L. Burnett, D.D. Ricker, S.L. Chamness, D.D. Ricker, S.L. Chamness, M.P. Maguire, J.K. Crone, D.S. Bredt, S.H. Snyder, and T.S. Chang Localization of nitric oxide synthase in the reproductive organs of the male rat Biol. Reprod. 52 1995 1 7
8. G. Burnstock Purinergic cotransmission Exp. Physiol. 94 2009 20 24
9. G. Burnstock, and A. Verkhratsky Vas deferens - a model used to establish sympathetic cotransmission Trends Pharmacol. Sci. 31 2010 131 139
10. J. Buvat Pathophysiology of premature ejaculation J. Sex. Med. 8 2011 316 327 10.1111/j.1743-6109.2011.02384.x
11. C.C. Carson, and T.F. Lue Phosphodiesterase type 5 inhibitors for erectile dysfunction BJU Int. 96 2005 257 280
12. S. Ceccatelli, J.M. Lundberg, X. Zhang, K. Aman, and T. Hökfelt Immunohistochemical demonstration of nitric oxide synthase in the peripheral autonomic nervous system Brain Res. 656 1994 381 395
13. J. Chen, G. Keren-Paz, Y. Bar-Yosef, and H. Matzkin The role of phosphodiesterase type 5 inhibitors in the management of premature ejaculation: a critical analysis of basic science and clinical data Eur. Urol. 52 2007 1331 1339
14. M.A. Claudino, F.H. da Silva, F.Z. Mónica, J.A. Rojas-Moscoso, G. De Nucci, and E. Antunes Long-term oral treatment with BAY 41-2272 ameliorates impaired corpus cavernosum relaxations in a nitric oxide-deficient rat model BJU Int. 108 2011 116 122
15. 2 + entry mediate increased pulmonary and systemic vascular resistance in L-NAME-treated rats Am. J. Physiol. Lung Cell. Mol. Physiol. 293 2007 L1306 L1313
16. O.V. Evgenov, P. Pacher, P.M. Schmidt, G. Haskó, H.H. Schmidt, and J.P.N. Stasch NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential Nat. Rev. Drug Discov. 5 2006 755 768
17. F. Giuliano, and W.J. Hellstrom The pharmacological treatment of premature ejaculation BJU Int. 102 2008 668 675
18. M. Grasso, F. Fortuna, C. Lania, and S. Blanco Ejaculatory disorders and alpha1-adrenoceptor antagonists therapy: clinical and experimental researches J. Transl. Med. 4 2006 31 35
19. S. Gur, S.C. Sikka, G.E. Knight, G. Burnstock, and W.J. Hellstrom Purinergic contraction of the rat vas deferens in L-NAME-induced hypertension: effect of sildenafil Asian J. Androl. 12 2010 415 421
20. J.K. Hennan, and J. Diamond Effect of NO donors on protein phosphorylation in intact vascular and nonvascular smooth muscles Am. J. Physiol. Heart Circ. Physiol. 280 2001 H1565 H1580
21. E.A. Jannini, and A. Lenzi Epidemiology of premature ejaculation Curr. Opin. Urol. 15 2005 399 403
22. E.A. Jannini, F. Lombardo, and A. Lenzi Correlation between ejaculatory and erectile dysfunction Int. J. Androl. 28 2005 40 45
23. J.S. Kalsi, R.W. Rees, A.J. Hobbs, M. Royle, P.D. Kell, D.J. Ralph, S. Moncada, and S. Cellek BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro J. Urol. 169 2003 761 766
24. + Exp. Physiol. 80 1995 721 733
25. L.R.A. Kiguti, and A.S. Pupo Investigation of the Effects of α(1)-adrenoceptor antagonism and L-type calcium channel blockade on ejaculation and vas deferens and seminal vesicle contractility in vitro J. Sex. Med. 2011 10.1111/j.1743-6109.2011.02410.x
26. -/-) Physiol. Behav. 67 1999 561 566
27. R. Mancina, S. Filippi, M. Marini, A. Morelli, L. Vignozzi, A. Salonia, F. Montorsi, N. Mondaini, G.B. Vannelli, S. Donati, F. Lotti, G. Forti, and M. Maggi Expression and functional activity of phosphodiesterase type 5 in human and rabbit vas deferens Mol. Hum. Reprod. 11 2005 107 115
28. D.R. Meldrum, J.C. Gambone, M.A. Morris, and L.J. Ignarro A multifaceted approach to maximize erectile function and vascular health Fertil. Steril. 94 2010 2514 2520
29. M.C. Michel Alpha1-adrenoceptors and ejaculatory function Br. J. Pharmacol. 152 2007 289 290
30. F.Z. Mónica, R. Reges, D. Cohen, R. Reges, D. Cohen, F.H. Silva, G. De Nucci, C.A. D'Ancona, and E. Antunes Long-term administration of BAY 41-2272 prevents bladder dysfunction in nitric oxide-deficient rats Neurourol. Urodyn. 30 2011 456 460
31. A.I. Patel, J.K. Hennan, and J. Diamond Activation of cGMP dependent protein kinase in rat vas deferens and distal colon is not accompanied by inhibition of contraction J. Pharmacol. Exp. Ther. 283 1997 894 900
32. A. Postorino, T. Vetri, L. Leggio, R. Serio, and F. Bonvissuto Nitric oxide as neuromodulator of sympathetic transmission in rat vas deferens J. Auton. Pharmacol. 18 1998 21 29
33. A. Schrammel, S. Behrends, K. Schmidt, D. Koesling, and B. Mayer Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylate cyclase Mol. Pharmacol. 50 1996 1 5
34. K.D. Schultz, K. Schultz, and G. Schultz Sodium nitroprusside and other smooth muscle-relaxants increase cyclic GMP levels in rat ductus deferens Nature 265 1977 750 751
35. P. Sneddon, D.P. Westfall, J. Colby, and J.S. Fedan A pharmacological investigation of the biphasic nature of the contractile response of rabbit and rat vas deferens to field stimulation Life Sci. 35 1984 1903 1912
36. J.P. Stasch, and A.J. Hobbs NO-independent, haem-dependent soluble guanylate cyclase stimulators Handb. Exp. Pharmacol. 191 2009 277 308
37. J.P. Stasch, E.M. Becker, C. Alonso-Alija, H. Apeler, K. Dembowsky, A. Feurer, R. Gerzer, T. Minuth, E. Perzborn, U. Pleiss, H. Schröder, W. Schroeder, E. Stahl, W. Steinke, A. Straub, and M. Schramm NO-independent regulatory site on soluble guanylate cyclase Nature 410 2001 212 215
38. C.E. Teixeira, F.B. Priviero, J. Todd Jr., and R.C. Webb Vasorelaxing effect of BAY 41-2272 in rat basilar artery: involvement of cGMP-dependent and independent mechanisms Hypertension 47 2006 596 602
39. C.E. Teixeira, F.B. Priviero, and R.C. Webb Molecular mechanisms underlying rat mesenteric artery vasorelaxation induced by the nitric oxide-independent soluble guanylyl cyclase stimulators BAY 41-2272 [5-cyclopropyl-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimi din-4-ylamine] and YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl Indazole] J. Pharmacol. Exp. Ther. 317 2006 258 266
40. S. Ventura, C.H.V. Hoyle, and G. Burnstock Sodium nitroprusside enhances contractions of the guinea-pig isolated vas deferens J. Pharm. Pharmacol. 50 1998 205 209
41. I. Vladimirova, N.H. Jurkiewicz, and A. Jurkiewicz Evidence for participation of nitric oxide in excitatory neurotransmission in rat vas deferens Life Sci. 55 1994 1123 1128
42. W.F. Wang, S. Minhas, and D.J. Ralph Phosphodiesterase 5 inhibitors in the treatment of premature ejaculation Int. J. Androl. 29 2006 503 509
43. A. Zini, M.K. O'Bryan, M.S. Magid, and P.N. Schlegel Immunohistochemical localization of endothelial nitric oxide synthase in human testis, epididymis, and vas deferens suggests a possible role for nitric oxide in spermatogenesis, sperm maturation, and programmed cell death Biol. Reprod. 55 1996 935 941