The role of PARP1 in the DNA damage response and its application in tumor therapy

Frontiers of Medicine in China

Volumn 6, Issue 2, 2012, Pages 156-164

  Wang, Zhifeng ^a   Wang, Fengli ^b   Tang, Tieshan ^b   Guo, Caixia ^a  

^a Chinese Academy of Sciences   (China)

^b INSTITUTE OF ZOOLOGY   (China)

Author keywords

cancer; DNA repair; NHEJ; PARP inhibitor; PARP1; synthetic lethality

Indexed keywords

ANTINEOPLASTIC AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, HUMAN; TUMOR MARKER;

DNA DAMAGE; DNA REPAIR; DRUG ANTAGONISM; DRUG RESISTANCE; HUMAN; METABOLISM; NEOPLASM; PHYSIOLOGY; REVIEW;

ANTINEOPLASTIC AGENTS; DNA DAMAGE; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; HUMANS; NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; TUMOR MARKERS, BIOLOGICAL;

EID: 84863485630     PISSN: 16737342     EISSN: 16737458     Source Type: Journal    
DOI: 10.1007/s11684-012-0197-3     Document Type: Review

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