메뉴 건너뛰기




Volumn 119, Issue 6, 2012, Pages 679-684

Ketogenic diet increases concentrations of kynurenic acid in discrete brain structures of young and adult rats

Author keywords

Brain; Cortex; Epilepsy; Hippocampus; Ketogenic diet; Kynurenic acid; Neurodegenerative disorders; Striatum

Indexed keywords

3 HYDROXYBUTYRIC ACID; GLUCOSE; KYNURENIC ACID;

EID: 84863466763     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-011-0750-2     Document Type: Article
Times cited : (29)

References (39)
  • 1
    • 0015691080 scopus 로고
    • An experimental animal model for the effect of ketogenic diet on epilepsy
    • Appleton DB, De Vivo DC (1973) An experimental animal model for the effect of ketogenic diet on epilepsy. Proc Aust Assoc Neurol 10:75-80
    • (1973) Proc Aust Assoc Neurol , vol.10 , pp. 75-80
    • Appleton, D.B.1    De Vivo, D.C.2
  • 2
    • 0028784927 scopus 로고
    • Systemic administration of kainate induces marked increases of endogenous kynurenic acid in various brain regions and plasma of rats
    • Baran H, Gramer M, Honack D, Loscher W (1995) Systemic administration of kainate induces marked increases of endogenous kynurenic acid in various brain regions and plasma of rats. Eur J Pharmacol 286:167-175
    • (1995) Eur J Pharmacol , vol.286 , pp. 167-175
    • Baran, H.1    Gramer, M.2    Honack, D.3    Loscher, W.4
  • 3
    • 0032902642 scopus 로고    scopus 로고
    • Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet
    • Bough KJ, Valiyil R, Han FT, Eagles DA (1999) Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet. Epilepsy Res 35:21-28
    • (1999) Epilepsy Res , vol.35 , pp. 21-28
    • Bough, K.J.1    Valiyil, R.2    Han, F.T.3    Eagles, D.A.4
  • 6
    • 79958092094 scopus 로고    scopus 로고
    • Novel aspect of ketone action: Beta-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro
    • Chmiel-Perzynska I, Kloc R, Perzynski A, Rudzki S, Urbanska EM (2011) Novel aspect of ketone action: beta-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro. Neurotoxic Res 20:40-50
    • (2011) Neurotoxic Res , vol.20 , pp. 40-50
    • Chmiel-Perzynska, I.1    Kloc, R.2    Perzynski, A.3    Rudzki, S.4    Urbanska, E.M.5
  • 7
    • 59149090373 scopus 로고    scopus 로고
    • Pharmacological manipulation of kynurenic acid: Potential in the treatment of psychiatric disorders
    • Erhardt S, Olsson SK, Engberg G (2009) Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders. CNS Drugs 23:91-101
    • (2009) CNS Drugs , vol.23 , pp. 91-101
    • Erhardt, S.1    Olsson, S.K.2    Engberg, G.3
  • 8
    • 78149405081 scopus 로고    scopus 로고
    • Ketosis and the ketogenic diet, 2010: Advances in treating epilepsy and other disorders
    • Freeman JM, Kossoff EH (2010) Ketosis and the ketogenic diet, 2010: advances in treating epilepsy and other disorders. Adv Pediatr 57:315-329
    • (2010) Adv Pediatr , vol.57 , pp. 315-329
    • Freeman, J.M.1    Kossoff, E.H.2
  • 9
    • 33748298884 scopus 로고    scopus 로고
    • Neuroprotective and disease-modifying effects of the ketogenic diet
    • Gasior M, Rogawski MA, Hartman AL (2006) Neuroprotective and disease-modifying effects of the ketogenic diet. Behav Pharmacol 17:431-439
    • (2006) Behav Pharmacol , vol.17 , pp. 431-439
    • Gasior, M.1    Rogawski, M.A.2    Hartman, A.L.3
  • 11
    • 0035213616 scopus 로고    scopus 로고
    • Caloric restriction inhibits seizure susceptibility in epileptic EL mice by reducing blood glucose
    • Greene AE, Todorova MT, McGowan R, Seyfried TN (2001) Caloric restriction inhibits seizure susceptibility in epileptic EL mice by reducing blood glucose. Epilepsia 42:1371-1378
    • (2001) Epilepsia , vol.42 , pp. 1371-1378
    • Greene, A.E.1    Todorova, M.T.2    McGowan, R.3    Seyfried, T.N.4
  • 12
    • 75849150001 scopus 로고    scopus 로고
    • Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
    • Han Q, Cai T, Tagle D, Li J (2010) Structure, expression, and function of kynurenine aminotransferases in human and rodent brains. Cell Mol Life Sci 67:353-368
    • (2010) Cell Mol Life Sci , vol.67 , pp. 353-368
    • Han, Q.1    Cai, T.2    Tagle, D.3    Li, J.4
  • 14
    • 38649113935 scopus 로고    scopus 로고
    • Efficacy of the ketogenic diet in the 6-Hz seizure test
    • Hartman AL, Lyle M, Rogawski MA, Gasior M (2008) Efficacy of the ketogenic diet in the 6-Hz seizure test. Epilepsia 49:334-339
    • (2008) Epilepsia , vol.49 , pp. 334-339
    • Hartman, A.L.1    Lyle, M.2    Rogawski, M.A.3    Gasior, M.4
  • 15
    • 0031868225 scopus 로고    scopus 로고
    • Interference with cellular energy metabolism reduces kynurenic acid formation in rat brain slices: Reversal by lactate and pyruvate
    • Hodgkins PS, Schwarcz R (1998) Interference with cellular energy metabolism reduces kynurenic acid formation in rat brain slices: reversal by lactate and pyruvate. Eur J Neurosci 10:1986-1994
    • (1998) Eur J Neurosci , vol.10 , pp. 1986-1994
    • Hodgkins, P.S.1    Schwarcz, R.2
  • 16
    • 77957131120 scopus 로고    scopus 로고
    • Kynurenines, neurodegeneration and Alzheimer's disease
    • Kincses ZT, Toldi J, Vecsei L (2010) Kynurenines, neurodegeneration and Alzheimer's disease. J Cell Mol Med 14:2045-2054
    • (2010) J Cell Mol Med , vol.14 , pp. 2045-2054
    • Kincses, Z.T.1    Toldi, J.2    Vecsei, L.3
  • 17
    • 33745119043 scopus 로고    scopus 로고
    • Enhancement of brain kynurenic acid production by anticonvulsants-novel mechanism of antiepileptic activity?
    • Kocki T,Wielosz M, Turski WA, Urbanska EM (2006) Enhancement of brain kynurenic acid production by anticonvulsants-novel mechanism of antiepileptic activity? Eur J Pharmacol 541:147-151
    • (2006) Eur J Pharmacol , vol.541 , pp. 147-151
    • Kocki Twielosz, M.1    Turski, W.A.2    Urbanska, E.M.3
  • 18
    • 60749090581 scopus 로고    scopus 로고
    • The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies
    • Maalouf M, Rho JM, Mattson MP (2009) The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Rev 59:293-315
    • (2009) Brain Res Rev , vol.59 , pp. 293-315
    • Maalouf, M.1    Rho, J.M.2    Mattson, M.P.3
  • 20
    • 67349261223 scopus 로고    scopus 로고
    • Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets
    • Mantis JG, Fritz CL, Stephen JM, Heinrichs C, Seyfried TN (2009) Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets. Epilepsy Behav 15:133-141
    • (2009) Epilepsy Behav , vol.15 , pp. 133-141
    • Mantis, J.G.1    Fritz, C.L.2    Stephen, J.M.3    Heinrichs, C.4    Seyfried, T.N.5
  • 21
    • 0023791093 scopus 로고
    • Kynurenic acid is present in the rat brain and its content increases during development and aging processes
    • Moroni F, Russi P, Carla V, Lombardi G (1988) Kynurenic acid is present in the rat brain and its content increases during development and aging processes. Neurosci Lett 94:145-150
    • (1988) Neurosci Lett , vol.94 , pp. 145-150
    • Moroni, F.1    Russi, P.2    Carla, V.3    Lombardi, G.4
  • 22
    • 16844362423 scopus 로고    scopus 로고
    • Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus
    • Moroni F, Cozzi A, Carpendo R, Cipriani G, Veneroni O, Izzo E (2005) Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus. Neuropharmacology 48:788-795
    • (2005) Neuropharmacology , vol.48 , pp. 788-795
    • Moroni, F.1    Cozzi, A.2    Carpendo, R.3    Cipriani, G.4    Veneroni, O.5    Izzo, E.6
  • 24
    • 77953617514 scopus 로고    scopus 로고
    • Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior
    • Potter MC, Elmer GI, Bergeron R, Albuquerque EX, Guidetti P, Wu HQ, Schwarcz R (2010) Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. Neuropsychopharmacol 35:1734-1742
    • (2010) Neuropsychopharmacol , vol.35 , pp. 1734-1742
    • Potter, M.C.1    Elmer, G.I.2    Bergeron, R.3    Albuquerque, E.X.4    Guidetti, P.5    Wu, H.Q.6    Schwarcz, R.7
  • 25
    • 69249101222 scopus 로고    scopus 로고
    • The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats
    • Prins ML, Hovda DA (2009) The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats. J Neurotrauma 26:1083-1093
    • (2009) J Neurotrauma , vol.26 , pp. 1083-1093
    • Prins, M.L.1    Hovda, D.A.2
  • 26
    • 79954609892 scopus 로고    scopus 로고
    • A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2. 1 J mouse model of Huntington's disease
    • Ruskin DN, Ross JL, Kawamura M, Ruiz TL, Geiger JD, Masino SA (2011) A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1 J mouse model of Huntington's disease. Physiol Behav 103:501-507
    • (2011) Physiol Behav , vol.103 , pp. 501-507
    • Ruskin, D.N.1    Ross, J.L.2    Kawamura, M.3    Ruiz, T.L.4    Geiger, J.D.5    Masino, S.A.6
  • 27
    • 78650420322 scopus 로고    scopus 로고
    • The ketogenic diet changes metabolite levels in hippocampal extracellular fluid
    • Samala R, Klein J, Borges K (2011) The ketogenic diet changes metabolite levels in hippocampal extracellular fluid. Neurochem Int 58:5-8
    • (2011) Neurochem Int , vol.58 , pp. 5-8
    • Samala, R.1    Klein, J.2    Borges, K.3
  • 28
    • 0842334499 scopus 로고    scopus 로고
    • Kynurenic acid synthesis in cerebral cortical slices of rats with progressing symptoms of thioacetamide-induced hepatic encephalopathy
    • Saran T, Hilgier W, Urbanska EM, Turski WA, Albrecht J (2004) Kynurenic acid synthesis in cerebral cortical slices of rats with progressing symptoms of thioacetamide-induced hepatic encephalopathy. J Neurosci Res 75:436-440
    • (2004) J Neurosci Res , vol.75 , pp. 436-440
    • Saran, T.1    Hilgier, W.2    Urbanska, E.M.3    Turski, W.A.4    Albrecht, J.5
  • 29
    • 0023810583 scopus 로고
    • Fluorimetric micro-determination of kynurenic acid, an endogenous blocker of neurotoxicity, by high-performance liquid chromatography
    • Shibata K (1988) Fluorimetric micro-determination of kynurenic acid, an endogenous blocker of neurotoxicity, by high-performance liquid chromatography. J Chromatogr 430:376-380
    • (1988) J Chromatogr , vol.430 , pp. 376-380
    • Shibata, K.1
  • 30
    • 0032830065 scopus 로고    scopus 로고
    • Animal models of the ketogenic diet: What have we learned, what can we learn?
    • Stafstrom CE (1999) Animal models of the ketogenic diet: what have we learned, what can we learn? Epilepsy Res 37:241-259
    • (1999) Epilepsy Res , vol.37 , pp. 241-259
    • Stafstrom, C.E.1
  • 31
    • 84857633029 scopus 로고    scopus 로고
    • The effects of electrical hippocampal kindling of seizures on amino acids and kynurenic acid concentrations in brain structures
    • doi:10.1007/s00702-011-0700-z
    • Szyndler J, Maciejak P, Turzynska D, Sobolewska A, Walkowiak J, Plaznik A (2011) The effects of electrical hippocampal kindling of seizures on amino acids and kynurenic acid concentrations in brain structures. J Neural Transm. doi:10.1007/s00702-011-0700-z
    • (2011) J Neural Transm
    • Szyndler, J.1    MacIejak, P.2    Turzynska, D.3    Sobolewska, A.4    Walkowiak, J.5    Plaznik, A.6
  • 34
    • 0024536479 scopus 로고
    • Rat brain slices produce and liberate kynurenic acid upon exposure to L-kynurenine
    • Turski WA, Gramsbergen JB, Traitler H, Schwarcz R (1989) Rat brain slices produce and liberate kynurenic acid upon exposure to L-kynurenine. J Neurochem 52:1629-1636
    • (1989) J Neurochem , vol.52 , pp. 1629-1636
    • Turski, W.A.1    Gramsbergen, J.B.2    Traitler, H.3    Schwarcz, R.4
  • 35
    • 67650178847 scopus 로고    scopus 로고
    • The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection
    • Vamos E, Pardutz A, Klivenyi P, Toldi J, Vecsei L (2009) The role of kynurenines in disorders of the central nervous system: possibilities for neuroprotection. J Neurol Sci 283:21-27
    • (2009) J Neurol Sci , vol.283 , pp. 21-27
    • Vamos, E.1    Pardutz, A.2    Klivenyi, P.3    Toldi, J.4    Vecsei, L.5
  • 36
    • 0025201208 scopus 로고
    • Intracerebroventricular injection of kynurenic acid, but not kynurenine, induces ataxia and stereotyped behavior in rats
    • Vecsei L, Beal MF (1990) Intracerebroventricular injection of kynurenic acid, but not kynurenine, induces ataxia and stereotyped behavior in rats. Brain Res Bull 25:623-627
    • (1990) Brain Res Bull , vol.25 , pp. 623-627
    • Vecsei, L.1    Beal, M.F.2
  • 37
    • 33745005516 scopus 로고    scopus 로고
    • Ammonia at pathophysiologically relevant concentrations activates kynurenic acid synthesis in cultured astrocytes and neurons
    • Wejksza K, Rzeski W, Turski WA, Hilgier W, Dybel A, Albrecht J (2006) Ammonia at pathophysiologically relevant concentrations activates kynurenic acid synthesis in cultured astrocytes and neurons. Neurotoxicology 27:619-622
    • (2006) Neurotoxicology , vol.27 , pp. 619-622
    • Wejksza, K.1    Rzeski, W.2    Turski, W.A.3    Hilgier, W.4    Dybel, A.5    Albrecht, J.6
  • 38
    • 70449523216 scopus 로고    scopus 로고
    • Kynurenines in chronic neurodegenerative disorders: Future therapeutic strategies
    • Zadori D, Klivenyi P, Vamos E, Fulop F, Toldi J, Vecsei L (2009) Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies. J Neural Transm 116:1403-1409
    • (2009) J Neural Transm , vol.116 , pp. 1403-1409
    • Zadori, D.1    Klivenyi, P.2    Vamos, E.3    Fulop, F.4    Toldi, J.5    Vecsei, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.