Novel aspect of ketone action: β-Hydroxybutyrate increases brain synthesis of kynurenic acid in vitro

Neurotoxicity Research

Volumn 20, Issue 1, 2011, Pages 40-50

  Chmiel Perzyńska, Iwona ^a   Kloc, Renata ^a   Perzyński, Adam ^a   Rudzki, Sławomir ^a   Urbańska, Ewa M ^a,b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

Hydroxybutyrate; Ketoacidosis; Ketogenic diet; Kynurenic acid; Protein kinase A; Rat brain

Indexed keywords

2,3,9,10,11,12 HEXAHYDRO 10 HYDROXY 9 METHYL 1 OXO 9,12 EPOXY 1H DIINDOLO [1,2,3 FG:3',2',1' KL]PYRROLO [3,4 I] [1,6] BENZODIAZOCINE 10 CARBOXYLIC ACID HEXYL ESTER; 3 HYDROXYBUTYRIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; GLUCOSE; KETONE BODY; KT 5270; KYNURENIC ACID; KYNURENINE AMINOTRANSFERASE; KYNURENINE AMINOTRANSFERASE I; KYNURENINE AMINOTRANSFERASE II; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN METABOLISM; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETIC KETOACIDOSIS; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; GLIA CELL; HYPOGLYCEMIA; IN VITRO STUDY; KETOACIDOSIS; KETOGENIC DIET; MALE; NONHUMAN; PH; PRIORITY JOURNAL; RAT;

3-HYDROXYBUTYRIC ACID; ANIMALS; AZOCINES; CELL CULTURE TECHNIQUES; CEREBRAL CORTEX; KETONE BODIES; KYNURENIC ACID; MALE; NEUROGLIA; RATS; RATS, WISTAR; TRANSAMINASES;

RATTUS;

EID: 79958092094     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-010-9220-0     Document Type: Article

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