Astaxanthin prevents changes in the activities of thioredoxin reductase and paraoxonase in hypercholesterolemic rabbits

Journal of Clinical Biochemistry and Nutrition

Volumn 51, Issue 1, 2012, Pages 42-49

  Augusti, Paula R ^a,b   Quatrin, Andréia ^c   Somacal, Sabrina ^c   Conterato, Greicy M M ^c   Sobieski, Rocheli ^c   Ruviaro, Amanda R ^c   Maurer, Luana H ^c   Duarte, Marta M F ^d   Roehrs, Miguel ^c   Emanuelli, Tatiana ^c  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE FEDERAL DO PAMPA   (Brazil)

^c FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^d UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

Atherosclerosis; Fatty acids; Oxidative stress

Indexed keywords

ARYLDIALKYLPHOSPHATASE; ASTAXANTHIN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MONOUNSATURATED FATTY ACID; OXIDIZED LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; THIOREDOXIN REDUCTASE; TRIACYLGLYCEROL; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; EXPERIMENTAL RABBIT; FATTY ACID BLOOD LEVEL; HYPERCHOLESTEROLEMIA; LIPID COMPOSITION; LIPID OXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; TRIACYLGLYCEROL BLOOD LEVEL;

ORYCTOLAGUS CUNICULUS;

EID: 84863459756     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.11-74     Document Type: Article

References (53)

1. Kruth HS. Lipoprotein cholesterol and atherosclerosis. Curr Mol Med 2001; 1: 633-653. (Pubitemid 33772940)
2. Prasad K, Kalra J. Oxygen free radicals and hypercholesterolemic atherosclerosis: effect of vitamin E. Am Heart J 1993; 125: 958-973. (Pubitemid 23117326)
3. Duarte MM, Rocha JB, Moresco RN, et al. Association between ischemia-modified albumin, lipids and inflammation biomarkers in patients with hypercholesterolemia. Clin Biochem 2009; 42: 666-671.
4. Berliner JA, Navab M, Fogelman AM, et al. Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. Circulation 1995; 91: 2488-2496.
5. Kondo A, Murunaka Y, Ohta I, et al. Relationships between triglyceride concentrations and LDL size evaluated by malonadehyde-modified LDL. Clin Chem 2001; 47: 893-900. (Pubitemid 32398041)
6. Nordberg J, Arnér ES. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 2001; 31: 1287-1312. (Pubitemid 33145299)
7. Furman C, Rundlöf AK, Larigauderie G, et al. Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins. Free Radic Biol Med 2004; 37: 71-85. (Pubitemid 38746652)
8. Wu Y, Yang L, Zhong L. Decreased serum levels of thioredoxin in patients with coronary artery disease plus hyperhomocysteinemia is strongly associated with the disease severity. Atherosclerosis 2010; 212: 351-355.
9. Jekell A, Hossain A, Alehagen U, Dahlström U, Rosé A. Elevated circulating levels of thioredoxin and stress in chronic heart failure. Eur J Heart Fail 2004; 6: 883-890. (Pubitemid 39536304)
10. Aviram M. Introduction to the serial review on paraoxonases, oxidative stress, and cardiovascular diseases. Free Radic Biol Med 2004; 37: 1301-1303. (Pubitemid 39349233)
11. Mackness B, Durrington P, McElduff P, et al. Low paraoxonase activity predicts coronary events in the Caerphilly prospective study. Circulation 2003; 107: 2775-2779. (Pubitemid 36705985)
12. Madrid AE, Vásques ZD, Levton AF, Mandiola C, Escobar FJA. Short-term Lycopersicum esculentum consumption may increase plasma high density lipoproteins and decrease oxidative stress. Rev Med Chil 2006; 134: 855-862.
13. Kurashige M, Okimasu E, Inoue M, Utsumi K. Inhibition of oxidative injury of biological membranes by astaxanthin. Physiol Chem Phys Med NMR 1990; 22: 27-38.
14. Pashkow FJ, Watumull DG, Campbell CL. Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease. Am J Cardiol 2008; 22: 580-680.
15. Jacobsson LS, Yuan XM, Ziedén B, Olsson AG. Effects of α-tocopherol and astaxanthin on LDL oxidation and atherosclerosis in WHHL rabbits. Atherosclerosis 2004; 173: 231-237. (Pubitemid 38469790)
16. Augusti PR, Conterato GM, Somacal S, et al. Astaxanthin reduces oxidative stress, but not aortic damage in atherosclerotic rabbits. J Cardiovasc Pharmacol Ther 2009; 14: 314-322.
17. Iwamoto T, Hosoda K, Hirano R, et al. Inhibition of low-density lipoprotein oxidation by astaxanthin. J Atheroscler Thromb 2000; 7: 216-222.
18. Li W, Hellsten A, Jacobsson LS, Blomqvist HM, Olsson AG, Yuan XM. Alpha-tocopherol and astaxanthin decrease macrophage infiltration, apoptosis and vulnerability in atheroma of hyperlipidaemic rabbits. J Mol Cell Cardiol 2004; 37: 969-978. (Pubitemid 39446822)
19. Choi HD, Kang HE, Yang SH, Lee MG, Shin WG. Pharmacokinetics and first-pass metabolism of astaxanthin in rats. Br J Nutr 2011; 105: 220-227.
20. Prasad K. Reduction of serum cholesterol and hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. Circulation 1999; 99: 1355-1362. (Pubitemid 29129922)
21. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-358. (Pubitemid 9194347)
22. Levine RL, Garland D, Oliver CN, et al. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990; 186: 464-478. (Pubitemid 20279989)
23. Holvoet P, Stassen JM, Van Cleemput J, Collen D, Vanhaecke J. Oxidized low density lipoproteins in patients with transplant-associated coronary artery disease. Arterioscler Thromb Vasc Biol 1998; 18: 100-107. (Pubitemid 28047605)
24. Wu R, Lefvert AK. Autoantibodies against oxidized low density lipoprotein (OxLDL): characterization of antibody isotype, subclass, affinity and effect on the macrophage uptake of oxLDL. Clin Exp Immunol 1995; 102: 174-180.
25. Bolayirli IM, Aslan M, Balci H, Altug T, Hacibekiroglu M, Seven A. Effects of atorvastatin therapy on hypercholesterolemic rabbits with respect to oxidative stress, nitric oxide pathway and homocysteine. Life Sci 2007; 81: 121-127. (Pubitemid 46921173)
26. Holmgren A, Björnstedt M. Thioredoxin and thioredoxin reductase. Methods Enzymol 1995; 252: 199-208.
27. Misra HP, Fridovich I. The role of superoxide anion in the auto-oxidation of epinephrine and a simple assay for superoxide-dismutase. J Biol Chem 1972; 247: 3170-3175.
28. Lepage G, Roy CC. Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res 1986; 27: 114-120. (Pubitemid 16045295)
29. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265-275.
30. Park JS, Kim HW, Mathison BD, et al. Astaxanthin uptake in domestic dogs and cats. Nutr Metab (Lond) 2010; 7: 52.
31. Coral-Hinostroza GN, Ytrestøyl T, Ruyter B, Bjerkeng B. Plasma appearance of unesterified astaxanthin geometrical E/Z and optical R/S isomers in men given single doses of a mixture of optical 3 and 3′R/S isomers of astaxanthin fatty acyl diesters. Comp Biochem Physiol C Toxicol Pharmacol 2004; 139: 99-110. (Pubitemid 39535793)
32. Ntambi JM. Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res 1999; 40: 1549-1558. (Pubitemid 29418696)
33. Rose HG. Origin of cholesterol esters in the blood of cholesterol-fed rabbits: relative contributions of serum lecithin-cholesterol acyltransferase and hepatic ester synthesis. Biochim Biophys Acta 1972; 260: 312-326.
34. Farmer JA, Gotto AM Jr. Dyslipidemia and the vulnerable plaque. Prog Cardiovasc Dis 2002; 44: 415-428. (Pubitemid 34680190)
35. Balkan J, Kanbaǧli O, Mehmetçik G, Mutlu- Türkoǧlu U, Aykaç-Toker G, Uysal M. Increased lipid peroxidation in serum and low-density lipoproteins associated with aging in humans. Int J Vitam Nutr Res 2002; 72: 315-320. (Pubitemid 35326069)
36. Bell JG, McEvoy J, Tocher DR, Sargent JR. Depletion of α-tocopherol and astaxanthin in Atlantic salmon (Salmo salar) affects autoxidative defense and fatty acid metabolism. J Nutr 2000; 130: 1800-1808. (Pubitemid 30451071)
37. Wingerath T, Stahl W, Sies H. Beta-cryptoxanthin selectively increases in human chylomicrons upon ingestion of tangerine concentrate rich in beta-cryptoxanthin esters. Arch Biochem Biophys 1995; 324: 385-390.
38. Shaw PX, Hörkkö S, Tsimikas S, et al. Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo. Arterioscler Thromb Vasc Biol 2001; 21: 1333-1339. (Pubitemid 34219841)
39. Augusti PR, Conterato GM, Somacal S, et al. Effect of astaxanthin on kidney function impairment and oxidative stress induced by mercuric chloride in rats. Food Chem Toxicol 2008; 46: 212-219. (Pubitemid 350235767)
40. Aas GH, Bjerkeng B, Storebakken T, Ruyter B. Blood appearance, metabolic transformation and plasma transport proteins of 14C-astaxanthin in Atlantic salmon (Salmo salar L.). Fish Physiol Biochem 1999; 21: 325-334. (Pubitemid 129645007)
41. Strålin P, Karlsson K, Johansson BO, Marklund SL. The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase. Arterioscler Thromb Vasc Biol 1995; 15: 2032-2036.
42. Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 1993; 91: 2546-2551. (Pubitemid 23182507)
43. Söderberg A, Sahaf B, Rosén A. Thioredoxin reductase, a redoxactive selenoprotein, is secreted by normal and neoplastic cells: presence in human plasma. Cancer Res 2000; 60: 2281-2289. (Pubitemid 30225195)
44. Björnstedt M, Hamberg M, Kumar S, Xue J, Holmgren A. Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. J Biol Chem 1995; 270: 11761-11764.
45. Hokamaki J, Kawano H, Soejima H, et al. Plasma thioredoxin levels in patients with unstable angina. Int J Cardiol 2005; 99: 225-231. (Pubitemid 40320794)
46. Furman C, Rundlöf AK, Larigauderie G, et al. Thioredoxin reductase 1 is upregulated in atherosclerotic plaques: specific induction of the promoter in human macrophages by oxidized low-density lipoproteins. Free Radic Biol Med 2004; 37: 71-85. (Pubitemid 38746652)
47. Wu X, Kang J, Xie C, et al. Dietary blueberries attenuate atherosclerosis in apolipoprotein E-deficient mice by upregulating antioxidant enzyme expression. J Nutr 2010; 140: 1628-1632.
48. Sezer EB, Sozmen EY, Nart D, Onat T. Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation. Vasc Health Risk Manag 2011; 7: 333-343.
49. Mackness M, Boullier A, Hennuyer N, et al. Paraoxonase activity is reduced by a pro-atherosclerotic diet in rabbits. Biochem Biophys Res Commun 2000; 269: 232-236. (Pubitemid 30440282)
50. Rajasingh H, Øyehaug L, Våge DI, Omholt SW. Carotenoid dynamics in Atlantic salmon. BMC Biol 2006; 4: 10.
51. Mackness MI, Durrington PN. HDL, its enzymes and its potential to influence lipid peroxidation. Atherosclerosis 1995; 115: 243-253.
52. Kwon EY, Do GM, Cho YY, Park YB, Jeon SM, Choi MS. Anti-atherogenic property of ferulic acid in apolipoprotein E-deficient mice fed Western diet: comparison with clofibrate. Food Chem Toxicol 2010; 48: 2298-2303.
53. -/- mice. Alcohol Clin Exp Res 2010; 34: 1535-1542.