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Volumn 25, Issue 3, 2012, Pages 651-656

Enzyme inhibition, antioxidant and antibacterial potential of vasicine isolated from Adhatoda vasica Nees

Author keywords

Acetylcholine esterase; Adhatoda vasica; Agar well diffusion assay; DPPH; FRAP; Trypsin

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ACETYLCHOLINESTERASE; TRYPSIN; VASICINE;

EID: 84863457587     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (27)

References (38)
  • 1
    • 0037216854 scopus 로고    scopus 로고
    • Medicinal chemistry approaches for the treatment and prevention of Alzheimer's disease
    • Bachurin SO (2003). Medicinal chemistry approaches for the treatment and prevention of Alzheimer's disease. Med. Res. Rev., 23: 48-88.
    • (2003) Med. Res. Rev. , vol.23 , pp. 48-88
    • Bachurin, S.O.1
  • 2
    • 0031729201 scopus 로고    scopus 로고
    • Ferric reducing/antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration
    • DOI 10.1016/S0076-6879(99)99005-5
    • Benzie IFF and Strain JJ (1999). Ferric reducing/ antioxidant power assay: Direct measure of the total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymol., 299: 15-27. (Pubitemid 28483878)
    • (1998) Methods in Enzymology , vol.299 , pp. 15-27
    • Benzie, I.F.F.1    Strain, J.J.2
  • 4
    • 0031885115 scopus 로고    scopus 로고
    • Screening of antiinflammatory medicinal plants used in traditional medicine against skin diseases
    • DOI 10.1002/(SICI)1099-1573(19980201)12:1<18::AID-PTR180>3.0.CO;2-3
    • Culler MJ, Giner RM and Recio MC (1998). Screening of anti-inflmatory medicinal plants used in traditional medicine against skin diseases. Phytother. Res., 12: 18-23. (Pubitemid 28076248)
    • (1998) Phytotherapy Research , vol.12 , Issue.1 , pp. 18-23
    • Cuellar, M.J.1    Giner, R.M.2    Recio, M.C.3    Just, M.J.4    Manez, S.5    Cerda, S.6    Rios, J.L.7
  • 8
    • 42949132291 scopus 로고    scopus 로고
    • Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates
    • DOI 10.1016/j.bmcl.2008.03.073, PII S0960894X08003582
    • Fang L, Kraus B, Lehmann J, Heilmann J, Zhang Y and Decker M (2008). Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates. Bioorg. Med. Chem. Lett., 18: 2905-2909. (Pubitemid 351608873)
    • (2008) Bioorganic and Medicinal Chemistry Letters , vol.18 , Issue.9 , pp. 2905-2909
    • Fang, L.1    Kraus, B.2    Lehmann, J.3    Heilmann, J.4    Zhang, Y.5    Decker, M.6
  • 9
    • 33845339435 scopus 로고    scopus 로고
    • Protease inhibitors in the clinic
    • Giovanni A and David PF (2005). Protease inhibitors in the clinic. Medl. Chem., 1: 71-104.
    • (2005) Medl. Chem. , vol.1 , pp. 71-104
    • Giovanni, A.1    David, P.F.2
  • 10
    • 0017573314 scopus 로고
    • Pharmacological investigations of vasicine and vasicinone: the alkaloids of Adhatoda vasica
    • Gupta OP, Sharma ML and Ghatak BJ (1977). Pharmacological investigations of vasicine and vasicinone the alkaloids of Adhatoda visica. Ind. J. Med. Res., 66: 680-691. (Pubitemid 8269770)
    • (1977) Indian Journal of Medical Research , vol.66 , Issue.4 , pp. 680-691
    • Gupta, O.P.1    Sharma, M.L.2    Ray, G.B.J.3    Atal, C.K.4
  • 11
    • 0021351203 scopus 로고
    • Oxygen toxicity, oxygen radicals, transition metals and disease
    • Halliwell B and Gutteridge JM (1984). Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem. J., 219: 1-14. (Pubitemid 14171443)
    • (1984) Biochemical Journal , vol.219 , Issue.1 , pp. 1-14
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 12
    • 0022006130 scopus 로고
    • Oxygen radicals and the nervous system
    • DOI 10.1016/0166-2236(85)90010-4
    • Halliwell B and Gutteridge JMC (1985). Oxygen radicals and the nervous system. Trends Neuroscience, 8:22-26. (Pubitemid 15171404)
    • (1985) Trends in Neurosciences , vol.8 , Issue.1 , pp. 22-26
    • Halliwell, B.1    Cutteridge, J.M.C.2
  • 13
    • 77953420657 scopus 로고    scopus 로고
    • Antidiabetic, antioxidant and antibacterial activities of leaf extracts of Adhatoda zeylanica. Medic (Acanthaceae)
    • Ilango K., Chitra V., Kanimozhi P and Balaji G (2009). Antidiabetic, antioxidant and antibacterial activities of leaf extracts of Adhatoda zeylanica. Medic (Acanthaceae). J. Pharm. Sci. Res., 1(2): 67-73.
    • (2009) J. Pharm. Sci. Res. , vol.1 , Issue.2 , pp. 67-73
    • Ilango, K.1    Chitra, V.2    Kanimozhi, P.3    Balaji, G.4
  • 14
    • 33645461862 scopus 로고    scopus 로고
    • Inhibition activities of natural products on serine proteases
    • Jedinák A, Maliar T, Cai GD and Nagy M (2006). Inhibition activities of natural products on serine proteases. Phytother. Res., 20: 214-217.
    • (2006) Phytother. Res. , vol.20 , pp. 214-217
    • Jedinák, A.1    Maliar, T.2    Cai, G.D.3    Nagy, M.4
  • 15
    • 0028167788 scopus 로고
    • 1H and 13C NMR assignments for some pyrroloquinqzoline alkaloids of Adhatoda vasica
    • Joshi BS, Bai Y and Puar MS (1994). 1H and 13C NMR assignments for some pyrroloquinqzoline alkaloids of Adhatoda vasica. J. Nat. Prod., 57: 953-962.
    • (1994) J. Nat. Prod. , vol.57 , pp. 953-962
    • Joshi, B.S.1    Bai, Y.2    Puar, M.S.3
  • 16
    • 77950483105 scopus 로고    scopus 로고
    • Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica L
    • Karthikeyan A, Shanthi V and Nagasathaya A (2009). Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica L. Int. J. Green Pharm., 3: 78-80.
    • (2009) Int. J. Green Pharm. , vol.3 , pp. 78-80
    • Karthikeyan, A.1    Shanthi, V.2    Nagasathaya, A.3
  • 17
    • 0002621769 scopus 로고
    • Possible mechanism for the protective role of the antioxidant in wine and plant foods
    • Kinsella JE, Frankel E, German B and Kanner J (1993). Possible mechanism for the protective role of the antioxidant in wine and plant foods. Food Technol., 47: 85-89.
    • (1993) Food Technol. , vol.47 , pp. 85-89
    • Kinsella, J.E.1    Frankel, E.2    German, B.3    Kanner, J.4
  • 19
    • 0035115147 scopus 로고    scopus 로고
    • Studies on the antioxidative activities of Hsian-tsao (Mesona procumbens Hemsl) leaf gum
    • Lai LS, Chou ST and Chao WW (2001). Studies on the antioxidative activities of Hsian-tsao (Mesona procumbens Hemsl) leaf gum. J. Agric. Food. Chem., 49: 963-968.
    • (2001) J. Agric. Food. Chem. , vol.49 , pp. 963-968
    • Lai, L.S.1    Chou, S.T.2    Chao, W.W.3
  • 20
    • 1842817379 scopus 로고    scopus 로고
    • Antimicrobial and antioxidant flavonoids from the root wood of Bolusanthus speciosus
    • Majinda RR, Paul and Gomotsang BM (2004). Antimicrobial and antioxidant flavonoids from the root wood of Bolusanthus speciosus. Phytochemistry, 65: 875-880.
    • (2004) Phytochemistry , vol.65 , pp. 875-880
    • Majinda, R.R.1    Paul2    Gomotsang, B.M.3
  • 21
    • 84855309027 scopus 로고    scopus 로고
    • Medicinal and biological significance of quinazoline: A highly important scaffold for drug discovery: A review
    • Manjula SN, Bharath EN and Divya B (2011). Medicinal and biological significance of quinazoline: A highly important scaffold for drug discovery: A review. Int. J. Pharma. Bio. Sci., 2(1): 780-809.
    • (2011) Int. J. Pharma. Bio. Sci. , vol.2 , Issue.1 , pp. 780-809
    • Manjula, S.N.1    Bharath, E.N.2    Divya, B.3
  • 22
    • 37849032383 scopus 로고    scopus 로고
    • Screening of Indian medicinal plants for acetylcholinesterase inhibitory activity
    • Mukherjee PK, Kumar V and Houghton PJ (2007). Screening of Indian medicinal plants for acetylcholinesterase inhibitory activity. Phytother. Res., 21: 1142-1145.
    • (2007) Phytother. Res. , vol.21 , pp. 1142-1145
    • Mukherjee, P.K.1    Kumar, V.2    Houghton, P.J.3
  • 24
    • 0042197464 scopus 로고    scopus 로고
    • Salvia for dementia therapy: Review of pharmacological activity and pilot tolerability clinical trial
    • DOI 10.1016/S0091-3057(03)00108-4
    • Perry NSL, Bollen C, Perry EK and Ballard C (2003). Salvia for dementia therapy: Review of pharmacological activity and pilot tolerability clinical trial. Pharmacol Biochem Behav., 75: 651-659. (Pubitemid 36936899)
    • (2003) Pharmacology Biochemistry and Behavior , vol.75 , Issue.3 , pp. 651-659
    • Perry, N.S.L.1    Bollen, C.2    Perry, E.K.3    Ballard, C.4
  • 25
    • 75849157563 scopus 로고
    • Demencias
    • 18th edn, Wyngaarden JB, Smith LH (eds). Interamericana McGraw-Hill, México
    • Plum F (1988). Demencias. In: Cecil. Tratado de Medicina Interna, 18th edn, Vol. 2, Wyngaarden JB, Smith LH (eds). Interamericana McGraw-Hill, México, pp.2311-2315.
    • (1988) Cecil. Tratado de Medicina Interna , vol.2 , pp. 2311-2315
    • Plum, F.1
  • 26
    • 0026025852 scopus 로고
    • The antioxidant nutrient and disease prevention; What do we know and what do we need to find out?
    • Pryor WA (1991). The antioxidant nutrient and disease prevention; What do we know and what do we need to find out? Am. J. Clin. Nutr., 53: 391-393.
    • (1991) Am. J. Clin. Nutr. , vol.53 , pp. 391-393
    • Pryor, W.A.1
  • 28
    • 9744238799 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products
    • DOI 10.1021/jm049655r
    • Rollinger JM, Hornick A, Langer T, Stuppner H and Prast H (2004). Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products. J. Med. Chem., 47: 6248-6254. (Pubitemid 39587249)
    • (2004) Journal of Medicinal Chemistry , vol.47 , Issue.25 , pp. 6248-6254
    • Rollinger, J.M.1    Hornick, A.2    Langer, T.3    Stuppner, H.4    Prast, H.5
  • 29
    • 70350464738 scopus 로고    scopus 로고
    • Synthesis, characterization and antimicrobial potential of transition metal complexes of triacetic lactone
    • Shahid S, Raza MA and Shafiq-Ur-Rehman (2009). Synthesis, characterization and antimicrobial potential of transition metal complexes of triacetic lactone. Afr. J. Biotech., 8(19): 5116-5121.
    • (2009) Afr. J. Biotech. , vol.8 , Issue.19 , pp. 5116-5121
    • Shahid, S.1    Raza, M.A.2    Shafiq-Ur-Rehman3
  • 30
    • 80053601241 scopus 로고    scopus 로고
    • Microbial transformation of vanillin isolated from Melia azedarach to Vanillyl alcohol followed by protease inhibition and antioxidant activity
    • Shahwar D, Raza MA, Ali T and Ahmad VU (2011b). Microbial transformation of vanillin isolated from Melia azedarach to Vanillyl alcohol followed by protease inhibition and antioxidant activity. J. Chem. Soc. Pak., 33(5): 715-719.
    • (2011) J. Chem. Soc. Pak. , vol.33 , Issue.5 , pp. 715-719
    • Shahwar, D.1    Raza, M.A.2    Ali, T.3    Ahmad, V.U.4
  • 31
    • 79952014934 scopus 로고    scopus 로고
    • Comparative study of antioxidant and antimicrobial activities of stem-bark extracts of Litchi chinensis and its organic fractions
    • Shahwar D, Raza MA, Mughal MAS, Abbasi MA and Ahmad VU (2010c). Comparative study of antioxidant and antimicrobial activities of stem-bark extracts of Litchi chinensis and its organic fractions. J. Chem. Soc. Pak., 32(3): 357-362.
    • (2010) J. Chem. Soc. Pak. , vol.32 , Issue.3 , pp. 357-362
    • Shahwar, D.1    Raza, M.A.2    Mughal, M.A.S.3    Abbasi, M.A.4    Ahmad, V.U.5
  • 32
    • 79952148115 scopus 로고    scopus 로고
    • Evaluation of acetylcholine esterase and protease inhibitory activity of scopolamine extracted from Datura innoxia
    • Shahwar D, Raza MA, Rehman SU and Kan T (2011a). Evaluation of acetylcholine esterase and protease inhibitory activity of scopolamine extracted from Datura innoxia. Asian J. Chem., 23(4): 1783-1785.
    • (2011) Asian J. Chem. , vol.23 , Issue.4 , pp. 1783-1785
    • Shahwar, D.1    Raza, M.A.2    Rehman, S.U.3    Kan, T.4
  • 33
  • 34
    • 77649093380 scopus 로고    scopus 로고
    • Acetyl cholinesterase inhibition potential and antioxidant activities of ferulic acid isolated from Impatiens bicolor Linn
    • Shahwar D, Rehman SU and Raza MA (2010a). Acetyl cholinesterase inhibition potential and antioxidant activities of ferulic acid isolated from Impatiens bicolor Linn. J. Med. Plant Res., 4(3): 260-266.
    • (2010) J. Med. Plant Res. , vol.4 , Issue.3 , pp. 260-266
    • Shahwar, D.1    Rehman, S.U.2    Raza, M.A.3
  • 35
    • 77249100906 scopus 로고    scopus 로고
    • Antioxidant activities of the selected plants from the family Euphorbiaceae, Lauraceae, Malvaceae and Balsaminaceae
    • Shahwar D, Shafiq UR, Naeem A, Ullah S and Raza MA (2010b). Antioxidant activities of the selected plants from the family Euphorbiaceae, Lauraceae, Malvaceae and Balsaminaceae: Afr. J. Biotech., 9(7): 1086-1096.
    • (2010) Afr. J. Biotech. , vol.9 , Issue.7 , pp. 1086-1096
    • Shahwar, D.1    Shafiq, U.R.2    Naeem, A.3    Ullah, S.4    Raza, M.A.5
  • 36
    • 84863460058 scopus 로고    scopus 로고
    • A study on antioxidant and anti-inflammatory activity of vasicine against lung damage in rats
    • Srinivasarao D, Indira AJ, Jayraaj R and Lakshmi MP (2006). A study on antioxidant and anti-inflammatory activity of vasicine against lung damage in rats. Indian J Allergy Asthma Immunol., 20(1): 1-7.
    • (2006) Indian J Allergy Asthma Immunol. , vol.20 , Issue.1 , pp. 1-7
    • Srinivasarao, D.1    Indira, A.J.2    Jayraaj, R.3    Lakshmi, M.P.4
  • 37
    • 0000087915 scopus 로고    scopus 로고
    • Antioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products
    • Velioglu YS, Mazza G, Gao L and Oomah BD (1998). Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products. J. Agric. Food Chem., 46: 4113-4117. (Pubitemid 128488501)
    • (1998) Journal of Agricultural and Food Chemistry , vol.46 , Issue.10 , pp. 4113-4117
    • Velioglu, Y.S.1    Mazza, G.2    Gao, L.3    Oomah, B.D.4
  • 38
    • 14844353926 scopus 로고    scopus 로고
    • A catalyst- and solvent-free selective approach to biologically important quinazolines and benzo[g]quinazoline
    • Vipan K, Chander M, Manish G and Mohinder PM (2005). A catalyst- and solvent-free selective approach to biologically important quinazolines and benzo[g]quinazoline. Tetrahedron, 61: 3533-3538.
    • (2005) Tetrahedron , vol.61 , pp. 3533-3538
    • Vipan, K.1    Chander, M.2    Manish, G.3    Mohinder, P.M.4


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