TPA-induced cell transformation provokes a complex formation between Pin1 and 90 kDa ribosomal protein S6 kinase 2

Molecular and Cellular Biochemistry

Volumn 367, Issue 1-2, 2012, Pages 85-92

  Cho, Young Sik ^a   Park, Seung Yeon ^a   Kim, Dong Joon ^b   Lee, Sang Han ^c   Woo, Kee Min ^c   Lee, Kyung Ae ^c   Lee, Yoon Jin ^c   Cho, Yong Yeon ^d   Shim, Jung Hyun ^c  

^a Keimyung University   (South Korea)

^b UNIVERSITY OF MINNESOTA   (United States)

^c Soonchunhyang University   (South Korea)

^d The Catholic University of Korea   (South Korea)

Author keywords

12 O tetradecanoylphorbol 13 acetate; Peptidyl cis trans prolyl isomerase; Post translational modification; Ribosomal S6 kinase 2; Tumorigenesis

Indexed keywords

90 KDA RIBOSOMAL PROTEIN S6 KINASE 2; PEPTIDYLPROLYL ISOMERASE PIN1; PHORBOL 13 ACETATE 12 MYRISTATE; S6 KINASE; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL TRANSFORMATION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; MICE; PEPTIDYLPROLYL ISOMERASE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; TETRADECANOYLPHORBOL ACETATE;

EID: 84863456586     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1322-y     Document Type: Article

References (29)

1. Wulf GM, Liou YC, Ryo A, Lee SW, Lu KP (2002) Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage. J Biol Chem 277:47976-47979 (Pubitemid 35470742)
2. Zhou XZ, Kops O, Werner A, Lu PJ, Shen M, Stoller G, Kullertz G, Stark M, Fischer G, Lu KP (2000) Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins. Mol Cell 6:873-883
3. Lu PJ, Zhou XZ, Shen M, Lu KP (1999) Function of WW domains as phosphoserine- or phosphothreonine-binding modules. Science 283:1325-1328
4. Yaffe MB, Schutkowski M, Shen M, Zhou XZ, Stukenberg PT, Rahfeld JU, Xu J, Kuang J, Kirschner MW, Fischer G, Cantley LC, Lu KP (1997) Sequence-specific and phosphorylationdependent proline isomerization: a potential mitotic regulatory mechanism. Science 278:1957-1960 (Pubitemid 28013239)
5. Lu KP, Zhou XZ (2007) The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease. Nat Rev Mol Cell Biol 8:904-916 (Pubitemid 47622559)
6. Mitchell DJ, Minchin RF (2009) Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1. Mol Pharmacol 76:388-395
7. Lu KP, Hanes SD, Hunter T (1996) A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature 380:544-547 (Pubitemid 26111332)
8. Shen M, Stukenberg PT, Kirschner MW, Lu KP (1998) The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Genes Dev 12:706-720 (Pubitemid 28134302)
9. Crenshaw DG, Yang J, Means AR, Kornbluth S (1998) The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1. EMBO J 17:1315-1327 (Pubitemid 28105511)
10. Lu PJ, Zhou XZ, Liou YC, Noel JP, Lu KP (2002) Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function. J Biol Chem 277:2381-2384 (Pubitemid 34953258)
11. Zhou XZ, Lu PJ, Wulf G, Lu KP (1999) Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism. Cell Mol Life Sci 56:788-806
12. Jensen CJ, Buch MB, Krag TO, Hemmings BA, Gammeltoft S, Frodin M (1999) 90-kDa Ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. J Biol Chem 274:27168-27176
13. Jones SW, Erikson E, Blenis J, Maller JL, Erikson RL (1988) A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases. Proc Natl Acad Sci USA 85:3377-3381
14. Ma Q, Guin S, Padhye SS, Zhou YQ, Zhang RW, Wang MH (2011) Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein. Mol Cancer 10:66-80
15. Wulf GM, Ryo A, Wulf GG, Lee SW, Niu T, Petkova V, Lu KP (2001) Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. EMBO J 20:3459-3472 (Pubitemid 32634353)
16. Tun-Kyi A, Finn G, Greenwood A, Nowak M, Lee TH, Asara JM, Tsokos GC, Fitzgerald K, Israel E, Li X, Exley M, Nicholson LK, Lu KP (2011) Essential role for the prolyl isomerase Pin1 in tolllike receptor signaling and type I interferon-mediated immunity. Nat Immunol 12:733-741
17. Sultana R, Boyd-Kimball D, Poon HF, Cai J, Pierce WM, Klein JB, Markesbery WR, Zhou XZ, Lu KP, Butterfield DA (2006) Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: a redox proteomics analysis. Neurobiol Aging 27:918-925
18. Cho YY, Yao K, Kim HG, Kang BS, Zheng D, Bode AM, Dong Z (2007) Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation. Cancer Res 67:8104-8112 (Pubitemid 47395145)
19. Urusova DV, Shim JH, Kim DJ, Jung SK, Zykova TA, Carper A, Bode AM, Dong Z (2011) Epigallocatechin-gallate suppresses tumorigenesis by directly targeting Pin1. Cancer Prev Res (Phila) 4:1366-1377
20. Cho YY, Yao K, Bode AM, Bergen HR 3rd, Madden BJ, Oh SM, Ermakova S, Kang BS, Choi HS, Shim JH, Dong Z (2007) RSK2 mediates muscle cell differentiation through regulation of NFAT3. J Biol Chem 282:8380-8392 (Pubitemid 47093615)
21. Choi HS, Bode AM, Shim JH, Lee SY, Dong Z (2009) c-Jun N-terminal kinase 1 phosphorylates Myt1 to prevent UVA-induced skin cancer. Mol Cell Biol 29:2168-2180
22. Zhu F, Choi BY, Ma WY, Zhao Z, Zhang Y, Cho YY, Choi HS, Imamoto A, Bode AM, Dong Z (2006) COOH-terminal Src kinase-mediated c-Jun phosphorylation promotes c-Jun degradation and inhibits cell transformation. Cancer Res 66:5729-5736 (Pubitemid 43927126)
23. Cho YS, Kang JW, Cho M, Cho CW, Lee S, Choe YK, Kim Y, Choi I, Park SN, Kim S, Dinarello CA, Yoon DY (2001) Down modulation of IL-18 expression by human papillomavirus type 16 E6 oncogene via binding to IL-18. FEBS Lett 501:139-145
24. Fujimori F, Takahashi K, Uchida C, Uchida T (1999) Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest. Biochem Biophys Res Commun 265:658-663
25. Dougherty MK, Muller J, Ritt DA, Zhou M, Zhou XZ, Copeland TD, Conrads TP, Veenstra TD, Lu KP, Morrison DK (2005) Regulation of Raf-1 by direct feedback phosphorylation. Mol Cell 17:215-224 (Pubitemid 40138617)
26. Li M, Stukenberg PT, Brautigan DL (2008) Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins. Biochemistry 47:292-300
27. Pan CQ, Liou YC, Low BC (2010) Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration. J Cell Sci 123:903-916
28. Lam PB, Burga LN, Wu BP, Hofstatter EW, Lu KP, Wulf GM (2008) Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability. Mol Cancer 7:91-102
29. Lee NY, Choi HK, Shim JH, Kang KW, Dong Z, Choi HS (2009) The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation. Carcinogenesis 30:671-681