Thymic gene transfer of myelin oligodendrocyte glycoprotein ameliorates the onset but not the progression of autoimmune demyelination

Molecular Therapy

Volumn 20, Issue 7, 2012, Pages 1349-1359

  Siatskas, Christopher ^a   Seach, Natalie ^a   Sun, Guizhi ^a   Emerson Webber, Ashley ^a   Silvain, Aude ^a   Toh, Ban Hock ^a   Alderuccio, Frank ^a   Thomas Backstrom B ^b   Boyd, Richard L ^a   Bernard, Claude C ^a  

^a MONASH UNIVERSITY   (Australia)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIBODY; CXCL9 CHEMOKINE; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; KERATINOCYTE DERIVED CHEMOKINE; LENTIVIRUS VECTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; RANTES; TUMOR NECROSIS FACTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIINFLAMMATORY ACTIVITY; AUTOIMMUNITY; CONFERENCE PAPER; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEMYELINATION; DISEASE COURSE; DRUG ADMINISTRATION ROUTE; DRUG TARGETING; GENE TRANSFER; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; NEUROPROTECTION; NONHUMAN; REGULATORY T LYMPHOCYTE; TH1 CELL; TH17 CELL; VIRAL GENE DELIVERY SYSTEM;

ANIMALIA; MUS;

EID: 84863445336     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2012.15     Document Type: Article

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