메뉴 건너뛰기




Volumn 41, Issue 6, 2012, Pages 463-469

The correlations between alteration of p16 gene and clinicopathological factors and prognosis in squamous cell carcinomas of the buccal mucosa

Author keywords

Buccal mucosa; Homozygous deletion; Methylation; P16 gene; Point mutation; Squamous cell carcinoma; Survival rate

Indexed keywords

PROTEIN P16;

EID: 84863424417     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2012.01132.x     Document Type: Article
Times cited : (17)

References (36)
  • 2
    • 0035523539 scopus 로고    scopus 로고
    • Demographics and occurrence of oral and pharyngeal cancers. The outcomes, the trends, the challenge
    • Silverman S Jr. Demographics and occurrence of oral and pharyngeal cancers. The outcomes, the trends, the challenge. J Am Dent Assoc 2001; 132: 7-11.
    • (2001) J Am Dent Assoc , vol.132 , pp. 7-11
    • Silverman Jr., S.1
  • 4
    • 62149136284 scopus 로고    scopus 로고
    • Molecular biology: an early detector of oral cancers
    • Ahmed SM, Mubeen K, Jigna VR. Molecular biology: an early detector of oral cancers. Ann Diagn Pathol 2009; 13: 140-5.
    • (2009) Ann Diagn Pathol , vol.13 , pp. 140-145
    • Ahmed, S.M.1    Mubeen, K.2    Jigna, V.R.3
  • 5
    • 0036141797 scopus 로고    scopus 로고
    • Clinicopathological significance of p16 gene expression in the surgical treatment of head and neck squamous cell carcinomas
    • Yuen PW, Man M, Lam KY, Kwong YL. Clinicopathological significance of p16 gene expression in the surgical treatment of head and neck squamous cell carcinomas. J Clin Pathol 2002; 55: 58-60.
    • (2002) J Clin Pathol , vol.55 , pp. 58-60
    • Yuen, P.W.1    Man, M.2    Lam, K.Y.3    Kwong, Y.L.4
  • 6
    • 18244367682 scopus 로고    scopus 로고
    • Cell cycle regulators as prognostic predictor of colorectal cancers
    • Jang SJ. Cell cycle regulators as prognostic predictor of colorectal cancers. Korean J Gastroenterol 2004; 44: 346-9.
    • (2004) Korean J Gastroenterol , vol.44 , pp. 346-349
    • Jang, S.J.1
  • 7
    • 0035835818 scopus 로고    scopus 로고
    • p16(MTS-1/CDKN2/INK4a) in cancer progression
    • Rocco JW, Sidransky D. p16(MTS-1/CDKN2/INK4a) in cancer progression. Exp Cell Res 2001; 264: 42-55.
    • (2001) Exp Cell Res , vol.264 , pp. 42-55
    • Rocco, J.W.1    Sidransky, D.2
  • 8
    • 0034739532 scopus 로고    scopus 로고
    • Inactivation of p16INK4a in primary tumors and cell lines of head and neck squamous cell carcinoma
    • Kim HS, Chung WB, Hong SH, et al. Inactivation of p16INK4a in primary tumors and cell lines of head and neck squamous cell carcinoma. Mol Cells 2000; 10: 557-65.
    • (2000) Mol Cells , vol.10 , pp. 557-565
    • Kim, H.S.1    Chung, W.B.2    Hong, S.H.3
  • 9
    • 33745887525 scopus 로고    scopus 로고
    • Correlation of clinicopathological features with immunohistochemical expression of cell cycle regulatory proteins p16 and retinoblastoma: distinct association with keratinisation and differentiation in oral cavity squamous cell carcinoma
    • Muirhead DM, Hoffman HT, Robinson RA. Correlation of clinicopathological features with immunohistochemical expression of cell cycle regulatory proteins p16 and retinoblastoma: distinct association with keratinisation and differentiation in oral cavity squamous cell carcinoma. J Clin Pathol 2006; 59: 711-5.
    • (2006) J Clin Pathol , vol.59 , pp. 711-715
    • Muirhead, D.M.1    Hoffman, H.T.2    Robinson, R.A.3
  • 10
    • 57649230131 scopus 로고    scopus 로고
    • Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma
    • Ohta S, Uemura H, Matsui Y, et al. Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 81-91.
    • (2009) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.107 , pp. 81-91
    • Ohta, S.1    Uemura, H.2    Matsui, Y.3
  • 11
    • 0034794887 scopus 로고    scopus 로고
    • The correlation between alteration of p16 gene and clinical status in oral squamous cell carcinoma
    • Tsai CH, Yang CC, Chou LS, Chou MY. The correlation between alteration of p16 gene and clinical status in oral squamous cell carcinoma. J Oral Pathol Med 2001; 30: 527-31.
    • (2001) J Oral Pathol Med , vol.30 , pp. 527-531
    • Tsai, C.H.1    Yang, C.C.2    Chou, L.S.3    Chou, M.Y.4
  • 12
    • 0034062368 scopus 로고    scopus 로고
    • Alterations of p16/MTS1 gene in oral squamous cell carcinomas from Taiwanese
    • Lin SC, Chang KW, Chang CS, et al. Alterations of p16/MTS1 gene in oral squamous cell carcinomas from Taiwanese. J Oral Pathol Med 2000; 29: 159-66.
    • (2000) J Oral Pathol Med , vol.29 , pp. 159-166
    • Lin, S.C.1    Chang, K.W.2    Chang, C.S.3
  • 13
    • 2442710439 scopus 로고    scopus 로고
    • Inactivation patterns of p16/INK4A in oral squamous cell carcinomas
    • Lee JK, Kim MJ, Hong SP, Hong SD. Inactivation patterns of p16/INK4A in oral squamous cell carcinomas. Exp Mol Med 2004; 36: 165-71.
    • (2004) Exp Mol Med , vol.36 , pp. 165-171
    • Lee, J.K.1    Kim, M.J.2    Hong, S.P.3    Hong, S.D.4
  • 16
    • 0037349716 scopus 로고    scopus 로고
    • Methylation and mutation analysis of p16 gene in gastric cancer
    • Ding Y, Le XP, Zhang QX, Du P. Methylation and mutation analysis of p16 gene in gastric cancer. World J Gastroenterol 2003; 9: 423-6.
    • (2003) World J Gastroenterol , vol.9 , pp. 423-426
    • Ding, Y.1    Le, X.P.2    Zhang, Q.X.3    Du, P.4
  • 17
    • 0036732023 scopus 로고    scopus 로고
    • Modes of silencing of p16 in development of esophageal squamous cell carcinoma
    • Tokugawa T, Sugihara H, Tani T, Hattori T. Modes of silencing of p16 in development of esophageal squamous cell carcinoma. Cancer Res 2002; 62: 4938-44.
    • (2002) Cancer Res , vol.62 , pp. 4938-4944
    • Tokugawa, T.1    Sugihara, H.2    Tani, T.3    Hattori, T.4
  • 18
    • 38749124349 scopus 로고    scopus 로고
    • p16(INK4A) genetic and epigenetic profiles differ in relation to age and site in head and neck squamous cell carcinomas
    • O'Regan EM, Toner ME, Finn SP, et al. p16(INK4A) genetic and epigenetic profiles differ in relation to age and site in head and neck squamous cell carcinomas. Hum Pathol 2008; 39: 452-8.
    • (2008) Hum Pathol , vol.39 , pp. 452-458
    • O'Regan, E.M.1    Toner, M.E.2    Finn, S.P.3
  • 19
    • 0034961861 scopus 로고    scopus 로고
    • Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas
    • Shintani S, Nakahara Y, Mihara M, Ueyama Y, Matsumura T. Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas. Oral Oncol 2001; 37: 498-504.
    • (2001) Oral Oncol , vol.37 , pp. 498-504
    • Shintani, S.1    Nakahara, Y.2    Mihara, M.3    Ueyama, Y.4    Matsumura, T.5
  • 20
    • 0032167474 scopus 로고    scopus 로고
    • Alter 6pRb and p16 protein alterations in human oral tumorigenesis
    • Pande P, Mathur M, Shukla NK, Ralhan R. Alter 6pRb and p16 protein alterations in human oral tumorigenesis. Oral Oncol 1998; 34: 396-403.
    • (1998) Oral Oncol , vol.34 , pp. 396-403
    • Pande, P.1    Mathur, M.2    Shukla, N.K.3    Ralhan, R.4
  • 21
    • 19544374893 scopus 로고    scopus 로고
    • Potential diagnostic use of p16INK4A, a new marker that correlates with dysplasia in oral squamoproliferative lesions
    • Gologan O, Barnes EL, Hunt JL. Potential diagnostic use of p16INK4A, a new marker that correlates with dysplasia in oral squamoproliferative lesions. Am J Surg Pathol 2005; 29: 792-6.
    • (2005) Am J Surg Pathol , vol.29 , pp. 792-796
    • Gologan, O.1    Barnes, E.L.2    Hunt, J.L.3
  • 22
    • 34247161466 scopus 로고    scopus 로고
    • Loss of tumour suppressor p16 expression in initial stages of oral oncogenesis
    • Vairaktaris E, Yapijakis C, Psyrri A, et al. Loss of tumour suppressor p16 expression in initial stages of oral oncogenesis. Anticancer Res 2007; 27: 979-84.
    • (2007) Anticancer Res , vol.27 , pp. 979-984
    • Vairaktaris, E.1    Yapijakis, C.2    Psyrri, A.3
  • 24
    • 0036673760 scopus 로고    scopus 로고
    • BMutational status of overexpressed p16 in head and neck cancer: evidence for germline mutation of p16/p14ARF
    • Lang JC, Borchers J, Danahey D, et al. BMutational status of overexpressed p16 in head and neck cancer: evidence for germline mutation of p16/p14ARF. Int J Oncol 2002; 21: 401-8.
    • (2002) Int J Oncol , vol.21 , pp. 401-408
    • Lang, J.C.1    Borchers, J.2    Danahey, D.3
  • 26
    • 0033031043 scopus 로고    scopus 로고
    • Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence
    • Orlow I, LaRue H, Osman I, et al. Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence. Am J Pathol 1999; 155: 105-13.
    • (1999) Am J Pathol , vol.155 , pp. 105-113
    • Orlow, I.1    LaRue, H.2    Osman, I.3
  • 27
    • 80052655064 scopus 로고    scopus 로고
    • Promoter methylation of p16(INK4A), hMLH1, and MGMT in liquid-based cervical cytology samples compared with clinicopathological findings and HPV presence
    • Spathis A, Aga E, Alepaki M, et al. Promoter methylation of p16(INK4A), hMLH1, and MGMT in liquid-based cervical cytology samples compared with clinicopathological findings and HPV presence. Infect Dis Obstet Gynecol 2011; 2011: 927861.
    • (2011) Infect Dis Obstet Gynecol , vol.2011 , pp. 927861
    • Spathis, A.1    Aga, E.2    Alepaki, M.3
  • 28
    • 0035436452 scopus 로고    scopus 로고
    • Analysis of a role for p16/CDKN2 expression and methylation patterns in human oral squamous cell carcinoma
    • Yakushiji T, Noma H, Shibahara T, et al. Analysis of a role for p16/CDKN2 expression and methylation patterns in human oral squamous cell carcinoma. Bull Tokyo Dent Coll 2001; 42: 159-68.
    • (2001) Bull Tokyo Dent Coll , vol.42 , pp. 159-168
    • Yakushiji, T.1    Noma, H.2    Shibahara, T.3
  • 29
    • 77955805905 scopus 로고    scopus 로고
    • Methylation of the p16 gene is frequently detected in lymphatic-invasive gastric cancer
    • Goto T, Mizukami H, Shirahata A, et al. Methylation of the p16 gene is frequently detected in lymphatic-invasive gastric cancer. Anticancer Res 2010; 30: 2701-3.
    • (2010) Anticancer Res , vol.30 , pp. 2701-2703
    • Goto, T.1    Mizukami, H.2    Shirahata, A.3
  • 30
    • 55649096866 scopus 로고    scopus 로고
    • P16 alterations increase the metastatic potential of endometrial carcinoma
    • Ignatov A, Bischoff J, Schwarzenau C, et al. P16 alterations increase the metastatic potential of endometrial carcinoma. Gynecol Oncol 2008; 111: 365-71.
    • (2008) Gynecol Oncol , vol.111 , pp. 365-371
    • Ignatov, A.1    Bischoff, J.2    Schwarzenau, C.3
  • 32
    • 79960697757 scopus 로고    scopus 로고
    • Prognostic significance of tumor-related genes hypermethylation detected in cancer-free surgical margins of oral squamous cell carcinomas
    • Supic G, Kozomara R, Jovic N, Zeljic K, Magic Z. Prognostic significance of tumor-related genes hypermethylation detected in cancer-free surgical margins of oral squamous cell carcinomas. Oral Oncol 2011; 47: 702-8.
    • (2011) Oral Oncol , vol.47 , pp. 702-708
    • Supic, G.1    Kozomara, R.2    Jovic, N.3    Zeljic, K.4    Magic, Z.5
  • 33
    • 36048972283 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization for detecting genomic alterations of cyclin D1 and p16 in oral squamous cell carcinomas
    • Uzawa N, Sonoda I, Myo K, Takahashi K, Miyamoto R, Amagasa T. Fluorescence in situ hybridization for detecting genomic alterations of cyclin D1 and p16 in oral squamous cell carcinomas. Cancer 2007; 110: 2230-9.
    • (2007) Cancer , vol.110 , pp. 2230-2239
    • Uzawa, N.1    Sonoda, I.2    Myo, K.3    Takahashi, K.4    Miyamoto, R.5    Amagasa, T.6
  • 34
    • 69349084287 scopus 로고    scopus 로고
    • Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: a prospective cohort study
    • Cao J, Zhou J, Gao Y, et al. Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: a prospective cohort study. Clin Cancer Res 2009; 15: 5178-83.
    • (2009) Clin Cancer Res , vol.15 , pp. 5178-5183
    • Cao, J.1    Zhou, J.2    Gao, Y.3
  • 35
    • 18444395545 scopus 로고    scopus 로고
    • Prognostic significance of p16INK4a alterations and 9p21 loss of heterozygosity in locally advanced laryngeal squamous cell carcinoma
    • Bazan V, Zanna I, Migliavacca M, et al. Prognostic significance of p16INK4a alterations and 9p21 loss of heterozygosity in locally advanced laryngeal squamous cell carcinoma. J Cell Physiol 2002; 192: 286-93.
    • (2002) J Cell Physiol , vol.192 , pp. 286-293
    • Bazan, V.1    Zanna, I.2    Migliavacca, M.3
  • 36
    • 77957376763 scopus 로고    scopus 로고
    • p16(INK4A) promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age-dependent manner
    • Su PF, Huang WL, Wu HT, Wu CH, Liu TY, Kao SY. p16(INK4A) promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age-dependent manner. Oral Oncol 2010; 46: 734-9.
    • (2010) Oral Oncol , vol.46 , pp. 734-739
    • Su, P.F.1    Huang, W.L.2    Wu, H.T.3    Wu, C.H.4    Liu, T.Y.5    Kao, S.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.