Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: Role of endogenous acetylcholine

Brain

Volumn 132, Issue 9, 2009, Pages 2336-2349

  Martella, Giuseppina ^a   Tassone, Annalisa ^b   Sciamanna, Giuseppe ^b   Platania, Paola ^a   Cuomo, Dario ^b   Viscomi, Maria Teresa ^b   Bonsi, Paola ^b   Cacci, Emanuele ^c   Biagioni, Stefano ^c   Usiello, Alessandro ^d,e   Bernardi, Giorgio ^a,b   Sharma, Nutan ^f   Standaert, David G ^g   Pisani, Antonio ^a,b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^e UNIVERSITY OF MOLISE   (Italy)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Acetylcholine; Dystonia; Electrophysiology; Striatum; Synaptic plasticity

Indexed keywords

ACETYLCHOLINE; CELL PROTEIN; MUSCARINIC M2 RECEPTOR; MUSCARINIC M4 RECEPTOR; TORSIN A; UNCLASSIFIED DRUG;

ACETYLCHOLINE BRAIN LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DYSTONIA; KNOCKOUT MOUSE; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MOUSE; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ANIMALS; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; DYSTONIC DISORDERS; EXCITATORY POSTSYNAPTIC POTENTIALS; GENOTYPE; MICE; MICE, TRANSGENIC; MOLECULAR CHAPERONES; NEURONAL PLASTICITY; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 71549148437     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awp194     Document Type: Article

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