Aberrant Cellular Behavior of Mutant TorsinA Implicates Nuclear Envelope Dysfunction in DYT1 Dystonia

Journal of Neuroscience

Volumn 24, Issue 11, 2004, Pages 2593-2601

  Gonzalez Alegre, Pedro ^a,b   Paulson, Henry L ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Dystonia; DYT1; Endoplasmic reticulum; Karmellas; Nuclear envelope; TorsinA

Indexed keywords

MUTANT PROTEIN; TORSIN A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BASE PAIRING; CELL CULTURE; CELL FUNCTION; CELL INCLUSION; CELL MEMBRANE; CELL NUCLEUS; CELL STRAIN; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; DISULFIDE BOND; ENDOPLASMIC RETICULUM; GENE DELETION; NERVE CELL LESION; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; TORSION DYSTONIA; TORSION DYSTONIA 1; WILD TYPE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CARRIER PROTEINS; CLONE CELLS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DYSTONIC DISORDERS; ENDOPLASMIC RETICULUM; GREEN FLUORESCENT PROTEINS; HUMANS; INCLUSION BODIES; LUMINESCENT PROTEINS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR CHAPERONES; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR ENVELOPE; PC12 CELLS; RATS; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 1642290757     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4461-03.2004     Document Type: Article

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