-
1
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan, M.B. et al. (2004) Cell-cycle checkpoints and cancer. Nature, 432, 316-323.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
-
2
-
-
0034237496
-
The G2-phase DNA-damage checkpoint
-
O'Connell, M.J. et al. (2000) The G2-phase DNA-damage checkpoint. Trends Cell Biol., 10, 296-303.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 296-303
-
-
O'Connell, M.J.1
-
3
-
-
33645288620
-
Protein-tyrosine phosphatases and cancer
-
Ostman, A. et al. (2006) Protein-tyrosine phosphatases and cancer. Nat. Rev. Cancer, 6, 307-320.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 307-320
-
-
Ostman, A.1
-
4
-
-
0032988653
-
Protein tyrosine phosphatases as negative regulators of mitogenic signaling
-
Chernoff, J. (1999) Protein tyrosine phosphatases as negative regulators of mitogenic signaling. J. Cell. Physiol., 180, 173-181.
-
(1999)
J. Cell. Physiol.
, vol.180
, pp. 173-181
-
-
Chernoff, J.1
-
5
-
-
25644449488
-
PTPase inhibition restores ERK1/2 phosphorylation and protects mammary epithelial cells from apoptosis
-
Furlong, F. et al. (2005) PTPase inhibition restores ERK1/2 phosphorylation and protects mammary epithelial cells from apoptosis. Biochem. Biophys. Res. Commun., 336, 1292-1299.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.336
, pp. 1292-1299
-
-
Furlong, F.1
-
6
-
-
58149457382
-
Bypass of hexavalent chromium-induced growth arrest by a protein tyrosine phosphatase inhibitor: enhanced survival and mutagenesis
-
Bae, D. et al. (2008) Bypass of hexavalent chromium-induced growth arrest by a protein tyrosine phosphatase inhibitor: enhanced survival and mutagenesis. Mutat. Res., 660, 40-46.
-
(2008)
Mutat. Res.
, vol.660
, pp. 40-46
-
-
Bae, D.1
-
7
-
-
18044403477
-
Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase
-
Yamashita, Y. et al. (2001) Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase. J. Biol. Chem., 276, 39012-39020.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39012-39020
-
-
Yamashita, Y.1
-
8
-
-
0037455717
-
[beta]-Hydroxyisovalerylshikonin induces apoptosis in human leukemia cells by inhibiting the activity of a polo-like kinase 1 (PLK1)
-
Masuda, Y. et al. [beta]-Hydroxyisovalerylshikonin induces apoptosis in human leukemia cells by inhibiting the activity of a polo-like kinase 1 (PLK1). Oncogene, 22, 1012-1023.
-
Oncogene
, vol.22
, pp. 1012-1023
-
-
Masuda, Y.1
-
9
-
-
4444321565
-
Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells
-
van Vugt, M.A. et al. (2004) Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells. Mol. Cell, 15, 799-811.
-
(2004)
Mol. Cell
, vol.15
, pp. 799-811
-
-
van Vugt, M.A.1
-
10
-
-
14644438485
-
Checkpoint adaptation and recovery: back with Polo after the break
-
van Vugt, M.A. et al. (2004) Checkpoint adaptation and recovery: back with Polo after the break. Cell Cycle, 3, 1383-1386.
-
(2004)
Cell Cycle
, vol.3
, pp. 1383-1386
-
-
van Vugt, M.A.1
-
11
-
-
0034282252
-
Polo-like kinase-1 is a target of the DNA damage checkpoint
-
Smits, V.A. et al. (2000) Polo-like kinase-1 is a target of the DNA damage checkpoint. Nat. Cell Biol., 2, 672-676.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 672-676
-
-
Smits, V.A.1
-
12
-
-
22844437779
-
Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage
-
Tsvetkov, L. et al. (2005) Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. Cell Cycle, 4, 166-171.
-
(2005)
Cell Cycle
, vol.4
, pp. 166-171
-
-
Tsvetkov, L.1
-
13
-
-
0030885666
-
CDC5 and CKII control adaptation to the yeast DNA damage checkpoint
-
Toczyski, D.P. et al. (1997) CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell, 90, 1097-1106.
-
(1997)
Cell
, vol.90
, pp. 1097-1106
-
-
Toczyski, D.P.1
-
14
-
-
33751301357
-
Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases
-
Syljuasen, R.G. et al. (2006) Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases. Cancer Res., 66, 10253-10257.
-
(2006)
Cancer Res
, vol.66
, pp. 10253-10257
-
-
Syljuasen, R.G.1
-
15
-
-
0038381451
-
Chromium (VI) activates ataxia telangiectasia mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest
-
Ha, L. et al. (2003) Chromium (VI) activates ataxia telangiectasia mutated (ATM) protein. Requirement of ATM for both apoptosis and recovery from terminal growth arrest. J. Biol. Chem., 278, 17885-17894.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17885-17894
-
-
Ha, L.1
-
16
-
-
66849113849
-
AKT1 mediates bypass of the G1/S checkpoint after genotoxic stress in normal human cells
-
Lal, M.A. et al. (2009) AKT1 mediates bypass of the G1/S checkpoint after genotoxic stress in normal human cells. Cell Cycle, 8, 1589-1602.
-
(2009)
Cell Cycle
, vol.8
, pp. 1589-1602
-
-
Lal, M.A.1
-
17
-
-
33847403132
-
In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1
-
Lansing, T.J. et al. (2007) In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1. Mol. Cancer Ther., 6, 450-459.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 450-459
-
-
Lansing, T.J.1
-
18
-
-
8844259700
-
Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX
-
Ha, L. et al. (2004) Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX. Carcinogenesis, 25, 2265-2274.
-
(2004)
Carcinogenesis
, vol.25
, pp. 2265-2274
-
-
Ha, L.1
-
19
-
-
0032913570
-
Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae
-
Swanson, R.L. et al. (1999) Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae. Mol. Cell. Biol., 19, 2929-2935.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2929-2935
-
-
Swanson, R.L.1
-
20
-
-
49549100682
-
Silencing of polo-like kinase (Plk) 1 via siRNA causes inhibition of growth and induction of apoptosis in human esophageal cancer cells
-
Bu, Y. et al. (2008) Silencing of polo-like kinase (Plk) 1 via siRNA causes inhibition of growth and induction of apoptosis in human esophageal cancer cells. Oncology, 74, 198-206.
-
(2008)
Oncology
, vol.74
, pp. 198-206
-
-
Bu, Y.1
-
21
-
-
0036142218
-
Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases
-
Crosio, C. et al. (2002) Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol. Cell. Biol., 22, 874-885.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 874-885
-
-
Crosio, C.1
-
22
-
-
18344366048
-
Getting in and out of mitosis with Polo-like kinase-1
-
van Vugt, M.A. et al. (2005) Getting in and out of mitosis with Polo-like kinase-1. Oncogene, 24, 2844-2859.
-
(2005)
Oncogene
, vol.24
, pp. 2844-2859
-
-
van Vugt, M.A.1
-
23
-
-
0029079267
-
Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function
-
Golsteyn, R.M. et al. (1995) Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. J. Cell Biol., 129, 1617-1628.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 1617-1628
-
-
Golsteyn, R.M.1
-
24
-
-
0037113919
-
Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase
-
Jang, Y.J. et al. (2002) Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase. J. Biol. Chem., 277, 44115-44120.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44115-44120
-
-
Jang, Y.J.1
-
25
-
-
33845624084
-
Polo-like kinase 1: target and regulator of transcriptional control
-
Martin, B.T. et al. (2006) Polo-like kinase 1: target and regulator of transcriptional control. Cell Cycle, 5, 2881-2885.
-
(2006)
Cell Cycle
, vol.5
, pp. 2881-2885
-
-
Martin, B.T.1
-
26
-
-
0037073722
-
Nuclear translocation of plk1 mediated by its bipartite nuclear localization signal
-
Taniguchi, E. et al. (2002) Nuclear translocation of plk1 mediated by its bipartite nuclear localization signal. J. Biol. Chem., 277, 48884-48888.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48884-48888
-
-
Taniguchi, E.1
-
27
-
-
0034048515
-
The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase
-
Roshak, A.K. et al. (2000) The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase. Cell. Signal., 12, 405-411.
-
(2000)
Cell. Signal.
, vol.12
, pp. 405-411
-
-
Roshak, A.K.1
-
28
-
-
35848940699
-
Polo-like kinase 1 may regulate G2/M transition of mouse fertilized eggs by means of inhibiting the phosphorylation of Tyr 15 of Cdc2
-
Zhang, Z. et al. (2007) Polo-like kinase 1 may regulate G2/M transition of mouse fertilized eggs by means of inhibiting the phosphorylation of Tyr 15 of Cdc2. Mol. Reprod. Dev., 74, 1247-1254.
-
(2007)
Mol. Reprod. Dev.
, vol.74
, pp. 1247-1254
-
-
Zhang, Z.1
-
29
-
-
0030924977
-
Plk is a functional homolog of Saccharomyces cerevisiae Cdc5, and elevated Plk activity induces multiple septation structures
-
Lee, K.S. et al. (1997) Plk is a functional homolog of Saccharomyces cerevisiae Cdc5, and elevated Plk activity induces multiple septation structures. Mol. Cell. Biol., 17, 3408-3417.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3408-3417
-
-
Lee, K.S.1
-
30
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. et al. (2000) The hallmarks of cancer. Cell, 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
-
31
-
-
27444439540
-
Effects of SOV-induced phosphatase inhibition and expression of protein tyrosine phosphatases in rat corneal endothelial cells
-
Chen, W.L. et al. (2005) Effects of SOV-induced phosphatase inhibition and expression of protein tyrosine phosphatases in rat corneal endothelial cells. Exp. Eye Res., 81, 570-580.
-
(2005)
Exp. Eye Res.
, vol.81
, pp. 570-580
-
-
Chen, W.L.1
-
32
-
-
33747585150
-
Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia
-
Matsumoto, J. et al. (2006) Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia. J. Pharmacol. Exp. Ther., 318, 982-991.
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.318
, pp. 982-991
-
-
Matsumoto, J.1
-
33
-
-
33644767315
-
Normal cells, but not cancer cells, survive severe Plk1 depletion
-
Liu, X. et al. (2006) Normal cells, but not cancer cells, survive severe Plk1 depletion. Mol. Cell. Biol., 26, 2093-2108.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2093-2108
-
-
Liu, X.1
-
34
-
-
2942615282
-
Polo-like kinases and the orchestration of cell division
-
Barr, F.A. et al. (2004) Polo-like kinases and the orchestration of cell division. Nat. Rev. Mol. Cell Biol., 5, 429-440.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 429-440
-
-
Barr, F.A.1
-
35
-
-
0033948542
-
Ste20-like kinase (SLK), a regulatory kinase for polo-like kinase (Plk) during the G2/M transition in somatic cells
-
Ellinger-Ziegelbauer, H. et al. (2000) Ste20-like kinase (SLK), a regulatory kinase for polo-like kinase (Plk) during the G2/M transition in somatic cells. Genes Cells, 5, 491-498.
-
(2000)
Genes Cells
, vol.5
, pp. 491-498
-
-
Ellinger-Ziegelbauer, H.1
-
36
-
-
0035834727
-
Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM-or ATR-dependent fashion
-
van Vugt, M.A. et al. (2001) Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM-or ATR-dependent fashion. J. Biol. Chem., 276, 41656-41660.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41656-41660
-
-
van Vugt, M.A.1
-
37
-
-
0032482986
-
Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk
-
Lee, K.S. et al. (1998) Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk. Proc. Natl Acad. Sci. USA, 95, 9301-9306.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 9301-9306
-
-
Lee, K.S.1
-
38
-
-
0642286495
-
Cyclin B1 and CDK1: nuclear localization and upstream regulators
-
Porter, L.A. et al. (2003) Cyclin B1 and CDK1: nuclear localization and upstream regulators. Prog. Cell Cycle Res., 5, 335-347.
-
(2003)
Prog. Cell Cycle Res.
, vol.5
, pp. 335-347
-
-
Porter, L.A.1
-
39
-
-
0345708258
-
Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms
-
O'Brien, T.J. et al. (2003) Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms. Mutat. Res., 533, 3-36.
-
(2003)
Mutat. Res.
, vol.533
, pp. 3-36
-
-
O'Brien, T.J.1
-
40
-
-
0032409983
-
Arrest of replication by mammalian DNA polymerases alpha and beta caused by chromium-DNA lesions
-
Bridgewater, L.C. et al. (1998) Arrest of replication by mammalian DNA polymerases alpha and beta caused by chromium-DNA lesions. Mol. Carcinog., 23, 201-206.
-
(1998)
Mol. Carcinog.
, vol.23
, pp. 201-206
-
-
Bridgewater, L.C.1
-
41
-
-
40949133430
-
Plx1 is required for chromosomal DNA replication under stressful conditions
-
Trenz, K. et al. (2008) Plx1 is required for chromosomal DNA replication under stressful conditions. EMBO J., 27, 876-885.
-
(2008)
EMBO J
, vol.27
, pp. 876-885
-
-
Trenz, K.1
-
42
-
-
0037031217
-
Effects of hexavalent chromium on the survival and cell cycle distribution of DNA repair-deficient S. cerevisiae
-
O'Brien, T.J. et al. (2002) Effects of hexavalent chromium on the survival and cell cycle distribution of DNA repair-deficient S. cerevisiae. DNA Repair (Amst.), 1, 617-627
-
(2002)
DNA Repair (Amst.)
, vol.1
, pp. 617-627
-
-
O'Brien, T.J.1
|