Understanding the roles of basophils: Breaking dawn

Immunology

Volumn 135, Issue 3, 2012, Pages 192-197

  Min, Booki ^a   Brown, Melissa A ^b   Legros, Graham ^c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c MALAGHAN INSTITUTE OF MEDICAL RESEARCH   (New Zealand)

Author keywords

Antibody responses; Basophils; Helper T cells (Th cells); Mast cells, CD4

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; COMPLEMENT COMPONENT C5A; DIPHTHERIA TOXIN; HOUSE DUST ALLERGEN; INTERLEUKIN 18; INTERLEUKIN 25; INTERLEUKIN 3; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 7 RECEPTOR ALPHA; PAPAIN; THYMIC STROMAL LYMPHOPOIETIN; TRANSCRIPTION FACTOR GATA 2;

ADOPTIVE TRANSFER; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; BASOPHIL; BIOACCUMULATION; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; DENDRITIC CELL; EFFECTOR CELL; ENTERITIS; EOSINOPHIL; HEPATITIS; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOMODULATION; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MAST CELL; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SCHISTOSOMIASIS; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; TH2 CELL; WILD TYPE;

ANIMALS; BASOPHILS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; HUMANS; INTERLEUKIN-4; MICE; MODELS, ANIMAL; MODELS, IMMUNOLOGICAL; TH2 CELLS;

EID: 84863401823     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2011.03530.x     Document Type: Review

References (63)

1. Falcone FH, Zillikens D, Gibbs BF. The 21st century renaissance of the basophil? Current insights into its role in allergic responses and innate immunity Exp Dermatol 2006; 15:855-64.
2. Ohnmacht C, Voehringer D. Basophil effector function and homeostasis during helminth infection. Blood 2009; 113:2816-25.
3. Min B, Prout M, Hu-Li J et al. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med 2004; 200:507-17.
4. Ben-Sasson SZ, Le Gros G, Conrad DH, Finkelman FD, Paul WE. Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines. Proc Natl Acad Sci U S A 1990; 87:1421-5.
5. Ugajin T, Kojima T, Mukai K et al. Basophils preferentially express mouse Mast Cell Protease 11 among the mast cell tryptase family in contrast to mast cells. J Leukoc Biol 2009; 86:1417-25.
6. Min B. Basophils: what they 'can do' versus what they 'actually do'. Nat Immunol 2008; 9:1333-9.
7. Obata K, Mukai K, Tsujimura Y et al. Basophils are essential initiators of a novel type of chronic allergic inflammation. Blood 2007; 110:913-20.
8. Denzel A, Maus UA, Rodriguez Gomez M et al. Basophils enhance immunological memory responses. Nat Immunol 2008; 9:733-42.
9. Sokol CL, Barton GM, Farr AG, Medzhitov R. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol 2008; 9:310-8.
10. Sullivan BM, Liang HE, Bando JK et al. Genetic analysis of basophil function in vivo. Nat Immunol 2011; 12:527-35.
11. Wada T, Ishiwata K, Koseki H et al. Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks. J Clin Invest 2010; 120:2867-75.
12. Ohnmacht C, Schwartz C, Panzer M, Schiedewitz I, Naumann R, Voehringer D. Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths. Immunity 2010; 33:364-74.
13. Voehringer D, Shinkai K, Locksley RM. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity 2004; 20:267-77.
14. Zhu J, Yamane H, Paul WE. Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol 2010; 28:445-89.
15. Bird JJ, Brown DR, Mullen AC et al. Helper T cell differentiation is controlled by the cell cycle. Immunity 1998; 9:229-37.
16. Le Gros G, Ben-Sasson SZ, Conrad DH et al. IL-3 promotes production of IL-4 by splenic non-B, non-T cells in response to Fc receptor cross-linkage. J Immunol 1990; 145:2500-6.
17. Hammad H, Plantinga M, Deswarte K et al. Inflammatory dendritic cells-not basophils-are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. J Exp Med 2010; 207:2097-111.
18. Phythian-Adams AT, Cook PC, Lundie RJ et al. CD11c depletion severely disrupts Th2 induction and development in vivo. J Exp Med 2010; 207:2089-96.
19. van Panhuys N, Prout M, Forbes E, Min B, Paul WE, Le Gros G. Basophils are the major producers of IL-4 during primary helminth infection. J Immunol 2011; 186:2719-28.
20. H2 cytokine-dependent immunity. Nat Immunol 2009; 10:697-705.
21. Shen T, Kim S, Do JS et al. T cell-derived IL-3 plays key role in parasite infection-induced basophil production but is dispensable for in vivo basophil survival. Int Immunol 2008; 20:1201-9.
22. Kim S, Prout M, Ramshaw H, Lopez AF, LeGros G, Min B. Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3. J Immunol 2010; 184:1143-7.
23. Nakanishi K. Basophils as APC in Th2 response in allergic inflammation and parasite infection. Curr Opin Immunol 2010; 22:814-20.
24. Siracusa MC, Perrigoue JG, Comeau MR, Artis D. New paradigms in basophil development, regulation and function. Immunol Cell Biol 2010; 88:275-84.
25. Sokol CL, Medzhitov R. Role of basophils in the initiation of Th2 responses. Curr Opin Immunol 2010; 22:73-7.
26. H2 responses. Nat Immunol 2009; 10:679-81.
27. Sokol CL, Chu NQ, Yu S, Nish SA, Laufer TM, Medzhitov R. Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat Immunol 2009; 10:713-20.
28. + T cells. Nat Immunol 2009; 10:706-12.
29. Ohnmacht C, Voehringer D. Basophils protect against reinfection with hookworms independently of mast cells and memory Th2 cells. J Immunol 2010; 184:344-50.
30. Nel HJ, Hams E, Saunders SP et al. Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice. J Immunol 2011; 186:4631-9.
31. Steeves EB, Allen JR. Tick resistance in mast cell-deficient mice: histological studies. Int J Parasitol 1991; 21:265-8.
32. Brown SJ, Barker RW, Askenase PW. Bovine resistance to Amblyomma americanum ticks: an acquired immune response characterized by cutaneous basophil infiltrates. Vet Parasitol 1984; 16:147-65.
33. Brown SJ, Galli SJ, Gleich GJ, Askenase PW. Ablation of immunity to Amblyomma americanum by anti-basophil serum: cooperation between basophils and eosinophils in expression of immunity to ectoparasites (ticks) in guinea pigs. J Immunol 1982; 129:790-6.
34. Brown SJ, Graziano FM, Askenase PW. Immune serum transfer of cutaneous basophil-associated resistance to ticks: mediation by 7SIgG1 antibodies. J Immunol 1982; 129:2407-12.
35. Saito H, Hatake K, Dvorak AM et al. Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins. Proc Natl Acad Sci U S A 1988; 85:2288-92.
36. Valent P, Schmidt G, Besemer J et al. Interleukin-3 is a differentiation factor for human basophils. Blood 1989; 73:1763-9.
37. Arinobu Y, Iwasaki H, Akashi K. Origin of basophils and mast cells. Allergol Int 2009; 58:21-8.
38. Arinobu Y, Iwasaki H, Gurish MF et al. Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis. Proc Natl Acad Sci U S A 2005; 102:18105-10.
39. Radtke F, Wilson A, Ernst B, MacDonald HR. The role of Notch signaling during hematopoietic lineage commitment. Immunol Rev 2002; 187:65-74.
40. Iwasaki H, Mizuno S, Arinobu Y et al. The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. Genes Dev 2006; 20:3010-21.
41. John LB, Ward AC. The Ikaros gene family: transcriptional regulators of hematopoiesis and immunity. Mol Immunol 2011; 48:1272-8.
42. Ohmori K, Luo Y, Jia Y et al. IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. J Immunol 2009; 182:2835-41.
43. Yoshimoto T, Tsutsui H, Tominaga K et al. IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils. Proc Natl Acad Sci U S A 1999; 96:13962-6.
44. Lantz CS, Boesiger J, Song CH et al. Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites. Nature 1998; 392:90-3.
45. Lantz CS, Min B, Tsai M, Chatterjea D, Dranoff G, Galli SJ. IL-3 is required for increases in blood basophils in nematode infection in mice and can enhance IgE-dependent IL-4 production by basophils in vitro. Lab Invest 2008; 88:1134-42.
46. Siracusa MC, Saenz SA, Hill DA et al. TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Nature 2011; 477:229-33.
47. Charles N, Hardwick D, Daugas E, Illei GG, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med 2010; 16:701-7.
48. H2 pathway. Nature 2011; 475:110-3.
49. Kroeger KM, Sullivan BM, Locksley RM. IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway. J Leukoc Biol 2009; 86:769-78.
50. Wang H, Mobini R, Fang Y et al. Allergen challenge of peripheral blood mononuclear cells from patients with seasonal allergic rhinitis increases IL-17RB, which regulates basophil apoptosis and degranulation. Clin Exp Allergy 2010; 40:1194-202.
51. Yoshimoto T, Nakanishi K. Roles of IL-18 in basophils and mast cells. Allergol Int 2006; 55:105-13.
52. Pecaric-Petkovic T, Didichenko SA, Kaempfer S, Spiegl N, Dahinden CA. Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. Blood 2009; 113:1526-34.
53. Suzukawa M, Iikura M, Koketsu R et al. An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J Immunol 2008; 181:5981-9.
54. Bieneman AP, Chichester KL, Chen YH, Schroeder JT. Toll-like receptor 2 ligands activate human basophils for both IgE-dependent and IgE-independent secretion. J Allergy Clin Immunol 2005; 115:295-301.
55. Eglite S, Pluss K, Dahinden CA. Requirements for C5a receptor-mediated IL-4 and IL-13 production and leukotriene C4 generation in human basophils. J Immunol 2000; 165:2183-9.
56. Ochensberger B, Rihs S, Brunner T, Dahinden CA. IgE-independent interleukin-4 expression and induction of a late phase of leukotriene C4 formation in human blood basophils. Blood 1995; 86:4039-49.
57. + cells through interaction with the VH3 region of IgE. J Immunol 2000; 164:589-95.
58. Hida S, Tadachi M, Saito T, Taki S. Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance. Blood 2005; 106:2011-7.
59. Charles N, Watford WT, Ramos HL et al. Lyn kinase controls basophil GATA-3 transcription factor expression and induction of Th2 cell differentiation. Immunity 2009; 30:533-43.
60. Kuroda E, Ho V, Ruschmann J et al. SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils. J Immunol 2009; 183:3652-60.
61. Kuroda E, Antignano F, Ho VW et al. SHIP represses Th2 skewing by inhibiting IL-4 production from basophils. J Immunol 2011; 186:323-32.
62. Wang LJ, Cao Y, Shi HN. Helminth infections and intestinal inflammation. World J Gastroenterol 2008; 14:5125-32.
63. Weinstock JV, Elliott DE. Helminths and the IBD hygiene hypothesis. Inflamm Bowel Dis 2009; 15:128-33.